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Scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia: a case report and review of the literature.
J Med Case Rep. 2019 Dec 07; 13(1):358.JM

Abstract

BACKGROUND

Scrub typhus is an acute infectious zoonotic disease caused by Orientia tsutsugamushi. Multi-organ dysfunction secondary to scrub typhus is hard to diagnose and has a high mortality rate. Only one case of scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia has been reported thus far. In this study, we report a second case of scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia, and we summarize its diagnosis and treatment.

CASE PRESENTATION

A 43-year-old Han Chinese woman, a sanitation worker, was admitted to our hospital after 7 days of a skin infection and 5 days of a sore throat with fever and dizziness. A physical examination revealed the presence of an eschar on the right side of her neck. She had a history of insect bites during her sanitation work. A diagnostic evaluation identified scrub typhus as the primary illness, which was associated with multi-organ dysfunction syndrome and immune thrombocytopenia. She recovered completely after 15 days of treatment and extensive symptomatic supportive care.

CONCLUSION

We report a second case of tsutsugamushi disease with multi-organ dysfunction syndrome and immune thrombocytopenia, which resolved after treatment and extensive care.

Authors+Show Affiliations

Department of Intensive Care Unit, Peking University Shenzhen Hospital, Shenzhen, 518036, People's Republic of China.Department of Intensive Care Unit, Peking University Shenzhen Hospital, Shenzhen, 518036, People's Republic of China. huanglei0248@163.com.Department of Intensive Care Unit, Peking University Shenzhen Hospital, Shenzhen, 518036, People's Republic of China. zhangwx@hotmail.com.

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

31810465

Citation

Li, Weijia, et al. "Scrub Typhus With Multi-organ Dysfunction Syndrome and Immune Thrombocytopenia: a Case Report and Review of the Literature." Journal of Medical Case Reports, vol. 13, no. 1, 2019, p. 358.
Li W, Huang L, Zhang W. Scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia: a case report and review of the literature. J Med Case Rep. 2019;13(1):358.
Li, W., Huang, L., & Zhang, W. (2019). Scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia: a case report and review of the literature. Journal of Medical Case Reports, 13(1), 358. https://doi.org/10.1186/s13256-019-2299-x
Li W, Huang L, Zhang W. Scrub Typhus With Multi-organ Dysfunction Syndrome and Immune Thrombocytopenia: a Case Report and Review of the Literature. J Med Case Rep. 2019 Dec 7;13(1):358. PubMed PMID: 31810465.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia: a case report and review of the literature. AU - Li,Weijia, AU - Huang,Lei, AU - Zhang,Weixing, Y1 - 2019/12/07/ PY - 2019/03/24/received PY - 2019/10/18/accepted PY - 2019/12/8/entrez PY - 2019/12/8/pubmed PY - 2020/6/18/medline KW - Immune thrombocytopenia KW - Multi-organ dysfunction syndrome KW - Scrub typhus SP - 358 EP - 358 JF - Journal of medical case reports JO - J Med Case Rep VL - 13 IS - 1 N2 - BACKGROUND: Scrub typhus is an acute infectious zoonotic disease caused by Orientia tsutsugamushi. Multi-organ dysfunction secondary to scrub typhus is hard to diagnose and has a high mortality rate. Only one case of scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia has been reported thus far. In this study, we report a second case of scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia, and we summarize its diagnosis and treatment. CASE PRESENTATION: A 43-year-old Han Chinese woman, a sanitation worker, was admitted to our hospital after 7 days of a skin infection and 5 days of a sore throat with fever and dizziness. A physical examination revealed the presence of an eschar on the right side of her neck. She had a history of insect bites during her sanitation work. A diagnostic evaluation identified scrub typhus as the primary illness, which was associated with multi-organ dysfunction syndrome and immune thrombocytopenia. She recovered completely after 15 days of treatment and extensive symptomatic supportive care. CONCLUSION: We report a second case of tsutsugamushi disease with multi-organ dysfunction syndrome and immune thrombocytopenia, which resolved after treatment and extensive care. SN - 1752-1947 UR - https://www.unboundmedicine.com/medline/citation/31810465/Scrub_typhus_with_multi_organ_dysfunction_syndrome_and_immune_thrombocytopenia:_a_case_report_and_review_of_the_literature_ L2 - https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-019-2299-x DB - PRIME DP - Unbound Medicine ER -