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Botulinum Toxin: Pharmacology and Injectable Administration for the Treatment of Primary Hyperhidrosis.
J Am Acad Dermatol. 2019 Dec 04 [Online ahead of print]JA

Abstract

Hyperhidrosis is a dermatological condition defined by excessive sweating beyond thermoregulatory needs with significant effects on patients' quality of life. Hyperhidrosis is categorized as primary or secondary: primary hyperhidrosis is mostly focal and idiopathic, whereas secondary hyperhidrosis is commonly generalized and caused by an underlying medical condition or use of medications. Various surgical and nonsurgical therapies exist for primary hyperhidrosis. Although botulinum toxin is one of the deadliest toxins known, when used in small doses, it is one of the most effective therapies for primary hyperhidrosis. Botulinum toxin injections are widely used as a second-line primary hyperhidrosis treatment option, when topical treatment strategies have failed. This article provides an overview of the commercially available botulinum toxin formulations and their applications for the treatment of primary hyperhidrosis.

Authors+Show Affiliations

Rutgers- Robert Wood Johnson Medical School, 675 Hoes Lane West, Piscataway, NJ 08854. Electronic address: shiri.nawrocki@gmail.com.Thomas Jefferson University, Department of Dermatology, 833 Chestnut St, Philadelphia, PA 19107.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

31811879

Citation

Nawrocki, Shiri, and Jisun Cha. "Botulinum Toxin: Pharmacology and Injectable Administration for the Treatment of Primary Hyperhidrosis." Journal of the American Academy of Dermatology, 2019.
Nawrocki S, Cha J. Botulinum Toxin: Pharmacology and Injectable Administration for the Treatment of Primary Hyperhidrosis. J Am Acad Dermatol. 2019.
Nawrocki, S., & Cha, J. (2019). Botulinum Toxin: Pharmacology and Injectable Administration for the Treatment of Primary Hyperhidrosis. Journal of the American Academy of Dermatology. https://doi.org/10.1016/j.jaad.2019.11.042
Nawrocki S, Cha J. Botulinum Toxin: Pharmacology and Injectable Administration for the Treatment of Primary Hyperhidrosis. J Am Acad Dermatol. 2019 Dec 4; PubMed PMID: 31811879.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Botulinum Toxin: Pharmacology and Injectable Administration for the Treatment of Primary Hyperhidrosis. AU - Nawrocki,Shiri, AU - Cha,Jisun, Y1 - 2019/12/04/ PY - 2019/06/11/received PY - 2019/11/15/revised PY - 2019/11/22/accepted PY - 2019/12/8/entrez PY - 2019/12/8/pubmed PY - 2019/12/8/medline KW - abobotulinumtoxinA KW - axillary hyperhidrosis KW - botulinum neurotoxin KW - botulinum toxin KW - clostridium bacteria KW - craniofacial hyperhidrosis KW - excessive sweating KW - incobotulinumtoxinA KW - onabotulinumtoxinA KW - palmar hyperhidrosis KW - plantar hyperhidrosis KW - prabotulinumtoxinA KW - primary hyperhidrosis KW - rimabotulinumtoxinB JF - Journal of the American Academy of Dermatology JO - J. Am. Acad. Dermatol. N2 - Hyperhidrosis is a dermatological condition defined by excessive sweating beyond thermoregulatory needs with significant effects on patients' quality of life. Hyperhidrosis is categorized as primary or secondary: primary hyperhidrosis is mostly focal and idiopathic, whereas secondary hyperhidrosis is commonly generalized and caused by an underlying medical condition or use of medications. Various surgical and nonsurgical therapies exist for primary hyperhidrosis. Although botulinum toxin is one of the deadliest toxins known, when used in small doses, it is one of the most effective therapies for primary hyperhidrosis. Botulinum toxin injections are widely used as a second-line primary hyperhidrosis treatment option, when topical treatment strategies have failed. This article provides an overview of the commercially available botulinum toxin formulations and their applications for the treatment of primary hyperhidrosis. SN - 1097-6787 UR - https://www.unboundmedicine.com/medline/citation/31811879/Botulinum_Toxin:_Pharmacology_and_Injectable_Administration_for_the_Treatment_of_Primary_Hyperhidrosis L2 - https://linkinghub.elsevier.com/retrieve/pii/S0190-9622(19)33134-2 DB - PRIME DP - Unbound Medicine ER -
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