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Carbohydrate Intolerance and Disaccharidase Measurement - a Mini-Review.
Clin Biochem Rev. 2019 Nov; 40(4):167-174.CB

Abstract

Carbohydrate intolerance is one of several syndromes and diseases which together are known as malabsorption syndromes. These include small intestinal bacterial overgrowth (SIBO), coeliac disease, intestinal lymphangiectasia, short bowel syndrome, tropical sprue and some inherited metabolic disorders such as galactosaemia and pyruvate kinase deficiency. Specifically, the malabsorption of sugars affects morbidity for millions of sufferers across the world. Disaccharidase measurement is used in the investigation of disorders of the gastrointestinal tract. Diagnosis is by endoscopic small bowel biopsy of the duodenum or jejunum with subsequent biochemical and histopathological analysis. The diagnosis of bowel disorders presents several challenges with numerous overlapping presentations and symptoms such as bloating, diarrhoea, constipation, flatulence, borborygmus, weight loss and severe discomfort.

Authors+Show Affiliations

Chemical Pathology, Pathology Queensland, Herston, Qld 4029, Australia.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

31857738

Citation

Burke, Matthew. "Carbohydrate Intolerance and Disaccharidase Measurement - a Mini-Review." The Clinical Biochemist. Reviews, vol. 40, no. 4, 2019, pp. 167-174.
Burke M. Carbohydrate Intolerance and Disaccharidase Measurement - a Mini-Review. Clin Biochem Rev. 2019;40(4):167-174.
Burke, M. (2019). Carbohydrate Intolerance and Disaccharidase Measurement - a Mini-Review. The Clinical Biochemist. Reviews, 40(4), 167-174. https://doi.org/10.33176/AACB-19-00025
Burke M. Carbohydrate Intolerance and Disaccharidase Measurement - a Mini-Review. Clin Biochem Rev. 2019;40(4):167-174. PubMed PMID: 31857738.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Carbohydrate Intolerance and Disaccharidase Measurement - a Mini-Review. A1 - Burke,Matthew, PY - 2019/12/21/entrez PY - 2019/12/21/pubmed PY - 2019/12/21/medline SP - 167 EP - 174 JF - The Clinical biochemist. Reviews JO - Clin Biochem Rev VL - 40 IS - 4 N2 - Carbohydrate intolerance is one of several syndromes and diseases which together are known as malabsorption syndromes. These include small intestinal bacterial overgrowth (SIBO), coeliac disease, intestinal lymphangiectasia, short bowel syndrome, tropical sprue and some inherited metabolic disorders such as galactosaemia and pyruvate kinase deficiency. Specifically, the malabsorption of sugars affects morbidity for millions of sufferers across the world. Disaccharidase measurement is used in the investigation of disorders of the gastrointestinal tract. Diagnosis is by endoscopic small bowel biopsy of the duodenum or jejunum with subsequent biochemical and histopathological analysis. The diagnosis of bowel disorders presents several challenges with numerous overlapping presentations and symptoms such as bloating, diarrhoea, constipation, flatulence, borborygmus, weight loss and severe discomfort. SN - 0159-8090 UR - https://www.unboundmedicine.com/medline/citation/31857738/Carbohydrate_Intolerance_and_Disaccharidase_Measurement_-_a_Mini-Review L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/31857738/ DB - PRIME DP - Unbound Medicine ER -
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