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Comparison of ropivacaine combined with sufentanil for epidural anesthesia and spinal-epidural anesthesia in labor analgesia.
BMC Anesthesiol. 2020 01 02; 20(1):1.BA

Abstract

BACKGROUND

To compare the application and efficacy of ropivacaine combined with sufentanil for continuous epidural anesthesia (CEA) and combined spinal-epidural anesthesia (CSEA) in labor analgesia.

METHODS

Three hundred sixty pregnant women requesting labor analgesia from October 2017 to August 2018 were selected retrospectively. According to the anesthetic method, subjects were divided into CSEA group and CEA group. Ropivacaine combined with sufentanil were used in all subjects. The labor time, visual analogue scale (VAS), Apgar score of newborn, adverse pregnancy outcomes and adverse drug reactions were observed.

RESULTS

There was no significant difference in pre-analgesia (T0) VAS scores between the two groups (P > 0.05). VAS scores of first stage of labor (T1), second stage of labor (T2) and third stage of labor (T3) in CSEA group were significantly lower than CEA group (P < 0.01). The onset time, T1 and total labor time in CSEA group were significantly shorter than CEA group (P < 0.01). There were no significant differences between T2 and T3 (P > 0.05). There were no significant differences in adverse pregnancy outcomes and Apgar scores at 1, 5 and 10 min after birth between the two groups (P > 0.05). The incidence of adverse drug outcomes in CSEA group was significantly lower than CEA group (P < 0.01). Maternal satisfaction in CSEA group was significantly higher than CEA group (P < 0.01).

CONCLUSION

Considering ropivacaine combined with sufentanil for CSEA achieved a shorter onset time and labor period, significant analgesic effect, lower adverse drug reactions rates and higher subject satisfaction than CEA, it may be worthy of clinical promotion and application.

Links

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Authors+Show Affiliations

Wang Y
Department of Anesthesiology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100029, China.
Xu M
Department of Anesthesiology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100029, China. xumingjun88@yeah.net.

MeSH

AdultAnalgesia, ObstetricalAnesthesia, EpiduralAnesthesia, ObstetricalAnesthesia, SpinalAnesthetics, IntravenousAnesthetics, LocalApgar ScoreCase-Control StudiesFemaleHumansInfant, NewbornLabor Stage, SecondLabor Stage, ThirdPain MeasurementPatient SatisfactionPregnancyPregnancy OutcomeRetrospective StudiesRopivacaineSufentanilYoung Adult

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

31898488

Citation

Wang, Yanshuang, and Mingjun Xu. "Comparison of Ropivacaine Combined With Sufentanil for Epidural Anesthesia and Spinal-epidural Anesthesia in Labor Analgesia." BMC Anesthesiology, vol. 20, no. 1, 2020, p. 1.
Wang Y, Xu M. Comparison of ropivacaine combined with sufentanil for epidural anesthesia and spinal-epidural anesthesia in labor analgesia. BMC Anesthesiol. 2020;20(1):1.
Wang, Y., & Xu, M. (2020). Comparison of ropivacaine combined with sufentanil for epidural anesthesia and spinal-epidural anesthesia in labor analgesia. BMC Anesthesiology, 20(1), 1. https://doi.org/10.1186/s12871-019-0855-y
Wang Y, Xu M. Comparison of Ropivacaine Combined With Sufentanil for Epidural Anesthesia and Spinal-epidural Anesthesia in Labor Analgesia. BMC Anesthesiol. 2020 01 2;20(1):1. PubMed PMID: 31898488.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of ropivacaine combined with sufentanil for epidural anesthesia and spinal-epidural anesthesia in labor analgesia. AU - Wang,Yanshuang, AU - Xu,Mingjun, Y1 - 2020/01/02/ PY - 2018/12/06/received PY - 2019/09/24/accepted PY - 2020/1/4/entrez PY - 2020/1/4/pubmed PY - 2021/1/12/medline KW - Combined spinal-epidural anesthesia KW - Continuous epidural anesthesia KW - Labor analgesia KW - Ropivacaine KW - Sufentanil SP - 1 EP - 1 JF - BMC anesthesiology JO - BMC Anesthesiol VL - 20 IS - 1 N2 - BACKGROUND: To compare the application and efficacy of ropivacaine combined with sufentanil for continuous epidural anesthesia (CEA) and combined spinal-epidural anesthesia (CSEA) in labor analgesia. METHODS: Three hundred sixty pregnant women requesting labor analgesia from October 2017 to August 2018 were selected retrospectively. According to the anesthetic method, subjects were divided into CSEA group and CEA group. Ropivacaine combined with sufentanil were used in all subjects. The labor time, visual analogue scale (VAS), Apgar score of newborn, adverse pregnancy outcomes and adverse drug reactions were observed. RESULTS: There was no significant difference in pre-analgesia (T0) VAS scores between the two groups (P > 0.05). VAS scores of first stage of labor (T1), second stage of labor (T2) and third stage of labor (T3) in CSEA group were significantly lower than CEA group (P < 0.01). The onset time, T1 and total labor time in CSEA group were significantly shorter than CEA group (P < 0.01). There were no significant differences between T2 and T3 (P > 0.05). There were no significant differences in adverse pregnancy outcomes and Apgar scores at 1, 5 and 10 min after birth between the two groups (P > 0.05). The incidence of adverse drug outcomes in CSEA group was significantly lower than CEA group (P < 0.01). Maternal satisfaction in CSEA group was significantly higher than CEA group (P < 0.01). CONCLUSION: Considering ropivacaine combined with sufentanil for CSEA achieved a shorter onset time and labor period, significant analgesic effect, lower adverse drug reactions rates and higher subject satisfaction than CEA, it may be worthy of clinical promotion and application. SN - 1471-2253 UR - https://www.unboundmedicine.com/medline/citation/31898488/Comparison_of_ropivacaine_combined_with_sufentanil_for_epidural_anesthesia_and_spinal_epidural_anesthesia_in_labor_analgesia_ DB - PRIME DP - Unbound Medicine ER -