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Using statewide death certificate data to understand trends and characteristics of polydrug overdose deaths in Tennessee, 2013-2017.
Ann Epidemiol. 2020 01; 41:43-48.e1.AE

Abstract

PURPOSE

Population-based data on trends and characteristics on polydrug overdoses are critically needed to help understand the changing drug epidemic in the United States, and to identify risk patterns and targets for overdose prevention for prescription and illicit opioid deaths. We conducted a statewide study in Tennessee to evaluate characteristics and trends of polydrug overdose deaths during 2013-2017.

METHODS

We identified polydrug overdose deaths using ICD-10 codes and literal cause-of-death text in the death statistical files. We evaluated trends, contributing drugs, and demographic characteristics of overdoses (n = 2567 single-drug and n = 4683 polydrug deaths). Average annual percent change estimates (AAPCs) with associated 95% CIs were estimated using Poisson regression.

RESULTS

Polydrug overdoses increased annually, with higher AAPC for polydrug compared with single-drug overdoses (AAPC: 13.6%, 95% CI: 10.6%-16.7% and 5.2%, 95% CI: 2.9%-7.5%, respectively). The highest increases in polydrug overdoses were observed in males (AAPC: 15.4%, non-Hispanic blacks (AAPC: 33.3%), and decedents aged 18-34 years (AAPC: 21.3%).

CONCLUSIONS

All drug and opioid polydrug deaths increased during 2013-2017, with the highest increases seen in males, blacks, and younger age groups. Over 80% of illicit opioid overdoses involved more than one drug, highlighting the need to go beyond opioids to prevent overdoses.

Authors+Show Affiliations

Tennessee Department of Health, Office of Informatics and Analytics, Nashville TN. Electronic address: molly.golladay@tn.gov.Tennessee Department of Health, Office of Informatics and Analytics, Nashville TN.Tennessee Department of Health, Office of Informatics and Analytics, Nashville TN.

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

31928897

Citation

Golladay, Molly, et al. "Using Statewide Death Certificate Data to Understand Trends and Characteristics of Polydrug Overdose Deaths in Tennessee, 2013-2017." Annals of Epidemiology, vol. 41, 2020, pp. 43-48.e1.
Golladay M, Donner K, Nechuta S. Using statewide death certificate data to understand trends and characteristics of polydrug overdose deaths in Tennessee, 2013-2017. Ann Epidemiol. 2020;41:43-48.e1.
Golladay, M., Donner, K., & Nechuta, S. (2020). Using statewide death certificate data to understand trends and characteristics of polydrug overdose deaths in Tennessee, 2013-2017. Annals of Epidemiology, 41, 43-e1. https://doi.org/10.1016/j.annepidem.2019.12.001
Golladay M, Donner K, Nechuta S. Using Statewide Death Certificate Data to Understand Trends and Characteristics of Polydrug Overdose Deaths in Tennessee, 2013-2017. Ann Epidemiol. 2020;41:43-48.e1. PubMed PMID: 31928897.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Using statewide death certificate data to understand trends and characteristics of polydrug overdose deaths in Tennessee, 2013-2017. AU - Golladay,Molly, AU - Donner,Kayle, AU - Nechuta,Sarah, Y1 - 2019/12/09/ PY - 2019/07/11/received PY - 2019/11/18/revised PY - 2019/12/04/accepted PY - 2020/1/14/pubmed PY - 2020/6/2/medline PY - 2020/1/14/entrez KW - Analgesics KW - Death certificate KW - Drug overdose deaths KW - Drug overdose mortality KW - Narcotics KW - Opioids KW - Polydrug KW - Polydrug use SP - 43 EP - 48.e1 JF - Annals of epidemiology JO - Ann Epidemiol VL - 41 N2 - PURPOSE: Population-based data on trends and characteristics on polydrug overdoses are critically needed to help understand the changing drug epidemic in the United States, and to identify risk patterns and targets for overdose prevention for prescription and illicit opioid deaths. We conducted a statewide study in Tennessee to evaluate characteristics and trends of polydrug overdose deaths during 2013-2017. METHODS: We identified polydrug overdose deaths using ICD-10 codes and literal cause-of-death text in the death statistical files. We evaluated trends, contributing drugs, and demographic characteristics of overdoses (n = 2567 single-drug and n = 4683 polydrug deaths). Average annual percent change estimates (AAPCs) with associated 95% CIs were estimated using Poisson regression. RESULTS: Polydrug overdoses increased annually, with higher AAPC for polydrug compared with single-drug overdoses (AAPC: 13.6%, 95% CI: 10.6%-16.7% and 5.2%, 95% CI: 2.9%-7.5%, respectively). The highest increases in polydrug overdoses were observed in males (AAPC: 15.4%, non-Hispanic blacks (AAPC: 33.3%), and decedents aged 18-34 years (AAPC: 21.3%). CONCLUSIONS: All drug and opioid polydrug deaths increased during 2013-2017, with the highest increases seen in males, blacks, and younger age groups. Over 80% of illicit opioid overdoses involved more than one drug, highlighting the need to go beyond opioids to prevent overdoses. SN - 1873-2585 UR - https://www.unboundmedicine.com/medline/citation/31928897/Using_statewide_death_certificate_data_to_understand_trends_and_characteristics_of_polydrug_overdose_deaths_in_Tennessee_2013_2017_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1047-2797(19)30451-X DB - PRIME DP - Unbound Medicine ER -