Abstract
The recent development of a cell-based assay that can detect specific autoantibodies revealed the clinical features of diseases associated with the anti-myelin oligodendrocyte glycoprotein (MOG) antibody. The anti-MOG antibody associated diseases may include inflammatory demyelinating central nervous system diseases such as neuromyelitis optica spectrum disorders, optic neuritis, myelitis, atypical multiple sclerosis, and encephalitis. Among them, anti-MOG antibody associated cortical encephalitis may develop seizure as one of the primary symptoms, present unique lateral or bilateral medial frontal cortical lesions on brain MRI FLAIR images. In acute phase, steroid pulse therapy and anti-epileptic drugs are required. In chronic phase, immunosuppressive drugs are often required to prevent relapses.
TY - JOUR
T1 - [Anti-myelin oligodendrocyte glycoprotein antibody associated encephalitis].
A1 - Fujimori,Juichi,
Y1 - 2020/01/19/
PY - 2020/1/21/pubmed
PY - 2020/8/21/medline
PY - 2020/1/21/entrez
KW - anti-myelin oligodendrocyte glycoprotein antibody
KW - cortical encephalitis
KW - epilepsy
KW - steroid
SP - 117
EP - 119
JF - Rinsho shinkeigaku = Clinical neurology
JO - Rinsho Shinkeigaku
VL - 60
IS - 2
N2 - The recent development of a cell-based assay that can detect specific autoantibodies revealed the clinical features of diseases associated with the anti-myelin oligodendrocyte glycoprotein (MOG) antibody. The anti-MOG antibody associated diseases may include inflammatory demyelinating central nervous system diseases such as neuromyelitis optica spectrum disorders, optic neuritis, myelitis, atypical multiple sclerosis, and encephalitis. Among them, anti-MOG antibody associated cortical encephalitis may develop seizure as one of the primary symptoms, present unique lateral or bilateral medial frontal cortical lesions on brain MRI FLAIR images. In acute phase, steroid pulse therapy and anti-epileptic drugs are required. In chronic phase, immunosuppressive drugs are often required to prevent relapses.
SN - 1882-0654
UR - https://www.unboundmedicine.com/medline/citation/31956198/[Anti_myelin_oligodendrocyte_glycoprotein_antibody_associated_encephalitis]_
L2 - https://dx.doi.org/10.5692/clinicalneurol.cn-001379
DB - PRIME
DP - Unbound Medicine
ER -