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Dental anomalies in patients with familial and sporadic cleft lip and palate.
J Biol Buccale. 1988 Sep; 16(3):185-90.JB

Abstract

Based on the frequency of occurrence of cleft lip and palate (CLP) in a family, a distinction has been made between familial and sporadic CLP. It was presumed that the genetic predisposition in familial CLP is high, while in sporadic CLP environmental factors play an important role. This study describes the possible relationship between the incidence of dental anomalies and the genetic predisposition of CLP in both the deciduous and permanent dentition. Dental anomalies were studied in 100 CLP patients and 38 control subjects. Neither the number of dental anomalies, nor the numbers of missing and supernumerary teeth differed significantly between familial and sporadic cases. A comparison between subjects with and without CLP showed a significant difference in the morphology of the dentition of the upper jaw. This difference was quantitative rather than qualitative. This study indicates a direct relationship between cleft formation and formation of the teeth, irrespective of the genetic predisposition and the severity of the cleft (i.e. uni- or bilateral).

Authors+Show Affiliations

Department of Orthodontics, Vrije Universiteit De Boelelaan, Amsterdam, The Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3198589

Citation

Carretero Quezada, M G., et al. "Dental Anomalies in Patients With Familial and Sporadic Cleft Lip and Palate." Journal De Biologie Buccale, vol. 16, no. 3, 1988, pp. 185-90.
Carretero Quezada MG, Hoeksma JB, van de Velde JP, et al. Dental anomalies in patients with familial and sporadic cleft lip and palate. J Biol Buccale. 1988;16(3):185-90.
Carretero Quezada, M. G., Hoeksma, J. B., van de Velde, J. P., Prahl-Andersen, B., & Kuijpers-Jagtman, A. M. (1988). Dental anomalies in patients with familial and sporadic cleft lip and palate. Journal De Biologie Buccale, 16(3), 185-90.
Carretero Quezada MG, et al. Dental Anomalies in Patients With Familial and Sporadic Cleft Lip and Palate. J Biol Buccale. 1988;16(3):185-90. PubMed PMID: 3198589.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dental anomalies in patients with familial and sporadic cleft lip and palate. AU - Carretero Quezada,M G, AU - Hoeksma,J B, AU - van de Velde,J P, AU - Prahl-Andersen,B, AU - Kuijpers-Jagtman,A M, PY - 1988/9/1/pubmed PY - 1988/9/1/medline PY - 1988/9/1/entrez SP - 185 EP - 90 JF - Journal de biologie buccale JO - J Biol Buccale VL - 16 IS - 3 N2 - Based on the frequency of occurrence of cleft lip and palate (CLP) in a family, a distinction has been made between familial and sporadic CLP. It was presumed that the genetic predisposition in familial CLP is high, while in sporadic CLP environmental factors play an important role. This study describes the possible relationship between the incidence of dental anomalies and the genetic predisposition of CLP in both the deciduous and permanent dentition. Dental anomalies were studied in 100 CLP patients and 38 control subjects. Neither the number of dental anomalies, nor the numbers of missing and supernumerary teeth differed significantly between familial and sporadic cases. A comparison between subjects with and without CLP showed a significant difference in the morphology of the dentition of the upper jaw. This difference was quantitative rather than qualitative. This study indicates a direct relationship between cleft formation and formation of the teeth, irrespective of the genetic predisposition and the severity of the cleft (i.e. uni- or bilateral). SN - 0301-3952 UR - https://www.unboundmedicine.com/medline/citation/3198589/Dental_anomalies_in_patients_with_familial_and_sporadic_cleft_lip_and_palate_ L2 - https://www.diseaseinfosearch.org/result/1672 DB - PRIME DP - Unbound Medicine ER -