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[Analysis of the first cluster of cases in a family of novel coronavirus pneumonia in Gansu Province].
Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Feb 17; 54(0):E005.ZY

Abstract

The epidemiological history and clinical characteristics of 7 cases of COVID-19 and 1 case of close contact in the first family aggregation epidemic of COVID-19 in Gansu Province were analyzed. The first patient A developed on January 22, 2020, with a history of residence in Wuhan, and confirmed severe cases of NCP on January 24, 2020; patient B, on January 23, 2020, diagnosed on January 31, severe cases; patient C, asymptomatic, diagnosed on January 27; patient D, asymptomatic, diagnosed on January 27; patient E, on January 24, diagnosed on January 28; patient F, asymptomatic, diagnosed on January 31; Patient G was asymptomatic and was diagnosed on January 31. In close contact, H was asymptomatic, PCR test was negative and asymptomatic, and he was discharged early. Among the 7 patients, 1 case died of (B) aggravation, and the other patients' condition was effectively controlled after active treatment. Except for the discharged cases, 5 cases were positive for COVID-19 specific IgM antibody and 1 case was negative. In this clustering outbreak, 4 patients remained asymptomatic, but PCR and IgM antibodies were positive, indicating that asymptomatic patients may be the key point to control the epidemic. Specific IgM antibody screening for patients whose pharyngeal swab nucleic acid test is negative but with ground glass-like lung lesions is very important for early detection and early isolation.

Authors+Show Affiliations

Department of Infectious Disease, Lanzhou Municipality Pulmonary Hospital, Lanzhou 730046, China.Department of Infectious Disease, Lanzhou Municipality Pulmonary Hospital, Lanzhou 730046, China.Department of Infectious Disease, Lanzhou Municipality Pulmonary Hospital, Lanzhou 730046, China.Gansu Province Center for Disease Control and Prevention, Lanzhou 730000, China.Department of Infectious Disease, Lanzhou Municipality Pulmonary Hospital, Lanzhou 730046, China.Department of Infectious Disease, Lanzhou Municipality Pulmonary Hospital, Lanzhou 730046, China.Department of Infectious Disease, Lanzhou Municipality Pulmonary Hospital, Lanzhou 730046, China.

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

32064855

Citation

Bai, S L., et al. "[Analysis of the First Cluster of Cases in a Family of Novel Coronavirus Pneumonia in Gansu Province]." Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine], vol. 54, no. 0, 2020, pp. E005.
Bai SL, Wang JY, Zhou YQ, et al. [Analysis of the first cluster of cases in a family of novel coronavirus pneumonia in Gansu Province]. Zhonghua Yu Fang Yi Xue Za Zhi. 2020;54(0):E005.
Bai, S. L., Wang, J. Y., Zhou, Y. Q., Yu, D. S., Gao, X. M., Li, L. L., & Yang, F. (2020). [Analysis of the first cluster of cases in a family of novel coronavirus pneumonia in Gansu Province]. Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine], 54(0), E005. https://doi.org/10.3760/cma.j.issn.0253-9624.2020.0005
Bai SL, et al. [Analysis of the First Cluster of Cases in a Family of Novel Coronavirus Pneumonia in Gansu Province]. Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Feb 17;54(0):E005. PubMed PMID: 32064855.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Analysis of the first cluster of cases in a family of novel coronavirus pneumonia in Gansu Province]. AU - Bai,S L, AU - Wang,J Y, AU - Zhou,Y Q, AU - Yu,D S, AU - Gao,X M, AU - Li,L L, AU - Yang,F, Y1 - 2020/02/17/ PY - 2020/2/18/entrez PY - 2020/2/18/pubmed PY - 2020/2/18/medline KW - Family cluster KW - Immunologlobulin M KW - Novel coronavirus pneumonia KW - Polymerase chain reaction SP - E005 EP - E005 JF - Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] JO - Zhonghua Yu Fang Yi Xue Za Zhi VL - 54 IS - 0 N2 - The epidemiological history and clinical characteristics of 7 cases of COVID-19 and 1 case of close contact in the first family aggregation epidemic of COVID-19 in Gansu Province were analyzed. The first patient A developed on January 22, 2020, with a history of residence in Wuhan, and confirmed severe cases of NCP on January 24, 2020; patient B, on January 23, 2020, diagnosed on January 31, severe cases; patient C, asymptomatic, diagnosed on January 27; patient D, asymptomatic, diagnosed on January 27; patient E, on January 24, diagnosed on January 28; patient F, asymptomatic, diagnosed on January 31; Patient G was asymptomatic and was diagnosed on January 31. In close contact, H was asymptomatic, PCR test was negative and asymptomatic, and he was discharged early. Among the 7 patients, 1 case died of (B) aggravation, and the other patients' condition was effectively controlled after active treatment. Except for the discharged cases, 5 cases were positive for COVID-19 specific IgM antibody and 1 case was negative. In this clustering outbreak, 4 patients remained asymptomatic, but PCR and IgM antibodies were positive, indicating that asymptomatic patients may be the key point to control the epidemic. Specific IgM antibody screening for patients whose pharyngeal swab nucleic acid test is negative but with ground glass-like lung lesions is very important for early detection and early isolation. SN - 0253-9624 UR - https://www.unboundmedicine.com/medline/citation/32064855/[Analysis_of_the_first_cluster_of_cases_in_a_family_of_novel_coronavirus_pneumonia_in_Gansu_Province]_ DB - PRIME DP - Unbound Medicine ER -
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