Tags

Type your tag names separated by a space and hit enter

Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection.
J Med Virol. 2020 06; 92(6):589-594.JM

Abstract

OBJECTIVE

This study aimed to assess the presence of novel coronavirus in tears and conjunctival secretions of SARS-CoV-2-infected patients.

METHODS

A prospective interventional case series study was performed, and 30 confirmed novel coronavirus pneumonia (NCP) patients were selected at the First Affiliated Hospital of Zhejiang University from 26 January 2020 to 9 February 2020. At an interval of 2 to 3 days, tear and conjunctival secretions were collected twice with disposable sampling swabs for reverse-transcription polymerase chain reaction (RT-PCR) assay.

RESULTS

Twenty-one common-type and nine severe-type NCP patients were enrolled. Two samples of tear and conjunctival secretions were obtained from the only one patient with conjunctivitis yielded positive RT-PCR results. Fifty-eight samples from other patents were all negative.

CONCLUSION

We speculate that SARS-CoV-2 may be detected in the tears and conjunctival secretions in NCP patients with conjunctivitis.

Authors+Show Affiliations

Department of Ophthalmology, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, Zhejiang, China.Department of Ophthalmology, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, Zhejiang, China.Department of Ophthalmology, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, Zhejiang, China.Department of Ophthalmology, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, Zhejiang, China.Department of Ophthalmology, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, Zhejiang, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32100876

Citation

Xia, Jianhua, et al. "Evaluation of Coronavirus in Tears and Conjunctival Secretions of Patients With SARS-CoV-2 Infection." Journal of Medical Virology, vol. 92, no. 6, 2020, pp. 589-594.
Xia J, Tong J, Liu M, et al. Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection. J Med Virol. 2020;92(6):589-594.
Xia, J., Tong, J., Liu, M., Shen, Y., & Guo, D. (2020). Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection. Journal of Medical Virology, 92(6), 589-594. https://doi.org/10.1002/jmv.25725
Xia J, et al. Evaluation of Coronavirus in Tears and Conjunctival Secretions of Patients With SARS-CoV-2 Infection. J Med Virol. 2020;92(6):589-594. PubMed PMID: 32100876.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection. AU - Xia,Jianhua, AU - Tong,Jianping, AU - Liu,Mengyun, AU - Shen,Ye, AU - Guo,Dongyu, Y1 - 2020/03/12/ PY - 2020/02/19/received PY - 2020/02/24/accepted PY - 2020/2/27/pubmed PY - 2020/7/1/medline PY - 2020/2/27/entrez KW - coronavirus KW - horizontal transmission KW - infection SP - 589 EP - 594 JF - Journal of medical virology JO - J. Med. Virol. VL - 92 IS - 6 N2 - OBJECTIVE: This study aimed to assess the presence of novel coronavirus in tears and conjunctival secretions of SARS-CoV-2-infected patients. METHODS: A prospective interventional case series study was performed, and 30 confirmed novel coronavirus pneumonia (NCP) patients were selected at the First Affiliated Hospital of Zhejiang University from 26 January 2020 to 9 February 2020. At an interval of 2 to 3 days, tear and conjunctival secretions were collected twice with disposable sampling swabs for reverse-transcription polymerase chain reaction (RT-PCR) assay. RESULTS: Twenty-one common-type and nine severe-type NCP patients were enrolled. Two samples of tear and conjunctival secretions were obtained from the only one patient with conjunctivitis yielded positive RT-PCR results. Fifty-eight samples from other patents were all negative. CONCLUSION: We speculate that SARS-CoV-2 may be detected in the tears and conjunctival secretions in NCP patients with conjunctivitis. SN - 1096-9071 UR - https://www.unboundmedicine.com/medline/citation/32100876/full_citation L2 - https://doi.org/10.1002/jmv.25725 DB - PRIME DP - Unbound Medicine ER -