Tags

Type your tag names separated by a space and hit enter

Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic.
Asian Pac J Allergy Immunol. 2020 Mar; 38(1):1-9.AP

Abstract

As the world is witnessing the epidemic of COVID-19, a disease caused by a novel coronavirus, SARS-CoV-2, emerging genetics and clinical evidences suggest a similar path to those of SARS and MERS. The rapid genomic sequencing and open access data, together with advanced vaccine technology, are expected to give us more knowledge on the pathogen itself, including the host immune response as well as the plan for therapeutic vaccines in the near future. This review aims to provide a comparative view among SARS-CoV, MERS-CoV and the newly epidemic SARS-CoV-2, in the hope to gain a better understanding of the host-pathogen interaction, host immune responses, and the pathogen immune evasion strategies. This predictive view may help in designing an immune intervention or preventive vaccine for COVID-19 in the near future.

Authors+Show Affiliations

Center of Excellence in Vaccine Research and Development (Chula Vaccine Research Center Chula VRC), Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. Center of Excellence in Vaccine Research and Development (Chula Vaccine Research Center Chula VRC), Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. Vaccines and Therapeutic Proteins Research Group, the Special Task Force for Activating Research (STAR), Chulalongkorn University, Bangkok 10330, Thailand.Center of Excellence in Vaccine Research and Development (Chula Vaccine Research Center Chula VRC), Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. Center of Excellence in Vaccine Research and Development (Chula Vaccine Research Center Chula VRC), Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. Center of Excellence in Immunology and Immune-mediated Diseases, Chulalongkorn University, Bangkok 10330, Thailand.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32105090

Citation

Prompetchara, Eakachai, et al. "Immune Responses in COVID-19 and Potential Vaccines: Lessons Learned From SARS and MERS Epidemic." Asian Pacific Journal of Allergy and Immunology, vol. 38, no. 1, 2020, pp. 1-9.
Prompetchara E, Ketloy C, Palaga T. Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic. Asian Pac J Allergy Immunol. 2020;38(1):1-9.
Prompetchara, E., Ketloy, C., & Palaga, T. (2020). Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic. Asian Pacific Journal of Allergy and Immunology, 38(1), 1-9. https://doi.org/10.12932/AP-200220-0772
Prompetchara E, Ketloy C, Palaga T. Immune Responses in COVID-19 and Potential Vaccines: Lessons Learned From SARS and MERS Epidemic. Asian Pac J Allergy Immunol. 2020;38(1):1-9. PubMed PMID: 32105090.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic. AU - Prompetchara,Eakachai, AU - Ketloy,Chutitorn, AU - Palaga,Tanapat, PY - 2020/2/28/pubmed PY - 2020/3/25/medline PY - 2020/2/28/entrez SP - 1 EP - 9 JF - Asian Pacific journal of allergy and immunology JO - Asian Pac J Allergy Immunol VL - 38 IS - 1 N2 - As the world is witnessing the epidemic of COVID-19, a disease caused by a novel coronavirus, SARS-CoV-2, emerging genetics and clinical evidences suggest a similar path to those of SARS and MERS. The rapid genomic sequencing and open access data, together with advanced vaccine technology, are expected to give us more knowledge on the pathogen itself, including the host immune response as well as the plan for therapeutic vaccines in the near future. This review aims to provide a comparative view among SARS-CoV, MERS-CoV and the newly epidemic SARS-CoV-2, in the hope to gain a better understanding of the host-pathogen interaction, host immune responses, and the pathogen immune evasion strategies. This predictive view may help in designing an immune intervention or preventive vaccine for COVID-19 in the near future. SN - 0125-877X UR - https://www.unboundmedicine.com/medline/citation/32105090/full_citation L2 - http://apjai-journal.org/wp-content/uploads/2020/03/1.pdf DB - PRIME DP - Unbound Medicine ER -