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Cardiovascular autonomic neuropathy: A silent killer with long reach.
Auton Neurosci. 2020 Feb 11; 225:102646.AN

Abstract

Cardiovascular autonomic neuropathy (CAN) is a common and deadly complication of diabetes mellitus, which is frequently overlooked in clinical practice due to its characteristic subtle presentation earlier in disease. Yet, timely detection of CAN may help implementation of tailored interventions to prevent its progression and mitigate the risk of associated complications, including cardiovascular disease (CVD), cardiac arrhythmias, myocardial dysfunction leading to congestive heart failure and all-cause mortality. This review highlights current CAN epidemiology trends, novel mechanisms linking CAN with other diabetes complications and current recommendations for diagnosis and management of the disease in the clinical setting.

Authors+Show Affiliations

Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, United States of America.University of Michigan Medical School, Ann Arbor, MI, United States of America.Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, United States of America.Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, United States of America. Electronic address: rpbusui@umich.edu.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32106052

Citation

Ang, Lynn, et al. "Cardiovascular Autonomic Neuropathy: a Silent Killer With Long Reach." Autonomic Neuroscience : Basic & Clinical, vol. 225, 2020, p. 102646.
Ang L, Dillon B, Mizokami-Stout K, et al. Cardiovascular autonomic neuropathy: A silent killer with long reach. Auton Neurosci. 2020;225:102646.
Ang, L., Dillon, B., Mizokami-Stout, K., & Pop-Busui, R. (2020). Cardiovascular autonomic neuropathy: A silent killer with long reach. Autonomic Neuroscience : Basic & Clinical, 225, 102646. https://doi.org/10.1016/j.autneu.2020.102646
Ang L, et al. Cardiovascular Autonomic Neuropathy: a Silent Killer With Long Reach. Auton Neurosci. 2020 Feb 11;225:102646. PubMed PMID: 32106052.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cardiovascular autonomic neuropathy: A silent killer with long reach. AU - Ang,Lynn, AU - Dillon,Brendan, AU - Mizokami-Stout,Kara, AU - Pop-Busui,Rodica, Y1 - 2020/02/11/ PY - 2019/11/27/received PY - 2020/01/30/revised PY - 2020/02/11/accepted PY - 2020/2/28/pubmed PY - 2020/2/28/medline PY - 2020/2/28/entrez KW - Cardiovascular autonomic dysfunction KW - Cardiovascular autonomic neuropathy KW - Cardiovascular disease KW - Diabetes mellitus SP - 102646 EP - 102646 JF - Autonomic neuroscience : basic & clinical JO - Auton Neurosci VL - 225 N2 - Cardiovascular autonomic neuropathy (CAN) is a common and deadly complication of diabetes mellitus, which is frequently overlooked in clinical practice due to its characteristic subtle presentation earlier in disease. Yet, timely detection of CAN may help implementation of tailored interventions to prevent its progression and mitigate the risk of associated complications, including cardiovascular disease (CVD), cardiac arrhythmias, myocardial dysfunction leading to congestive heart failure and all-cause mortality. This review highlights current CAN epidemiology trends, novel mechanisms linking CAN with other diabetes complications and current recommendations for diagnosis and management of the disease in the clinical setting. SN - 1872-7484 UR - https://www.unboundmedicine.com/medline/citation/32106052/Cardiovascular_autonomic_neuropathy:_A_silent_killer_with_long_reach L2 - https://linkinghub.elsevier.com/retrieve/pii/S1566-0702(19)30291-7 DB - PRIME DP - Unbound Medicine ER -
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