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Clinical Characteristics of Imported Cases of Coronavirus Disease 2019 (COVID-19) in Jiangsu Province: A Multicenter Descriptive Study.
Clin Infect Dis. 2020 07 28; 71(15):706-712.CI

Abstract

BACKGROUND

We aimed to report the clinical characteristics of imported cases of coronavirus disease 2019 (COVID-19) in Jiangsu Province.

METHODS

We retrospectively investigated the clinical, imaging, and laboratory characteristics of confirmed cases of COVID-19 with World Health Organization interim guidance in 3 grade IIIA hospitals of Jiangsu from 22 January to 14 February 2020. Real-time RT-PCR was used to detect the new coronavirus in respiratory samples.

RESULTS

Of the 80 patients infected with COVID-19, 41 were female, with a median age of 46.1 years. Except for 3 severe patients, the rest of the 77 patients exhibited mild or moderate symptoms. Nine patients were unconfirmed until a third nucleic acid test; 38 cases had a history of chronic diseases. The main clinical manifestations of the patients were fever and cough, which accounted for 63 (78.75%) and 51 (63.75%) cases, respectively. Only 3 patients (3.75%) showed liver dysfunction. Imaging examination showed that 55 patients (68.75%) showed abnormal density shadow and 25 cases (31.25%) had no abnormal density shadow in the parenchyma of both lungs. Currently, 21 cases have been discharged from the hospital, and no patient died. The average length of stay for discharged patients was 8 days.

CONCLUSIONS

Compared with the cases in Wuhan, the cases in Jiangsu exhibited mild or moderate symptoms and no obvious gender susceptibility. The proportion of patients having liver dysfunction and abnormal CT imaging was relatively lower than that in Wuhan. Notably, infected patients may be falsely excluded based on 2 consecutively negative respiratory pathogenic nucleic acid test results.

Authors+Show Affiliations

State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. Department of Laboratory Medicine, The First People's Hospital of Yancheng City, Yancheng, China.Department of Laboratory Medicine, The Fifth People's Hospital of Wuxi, Affiliated to Jiangnan University, Wuxi, China.Department of Respiration, The Fifth People's Hospital of Wuxi, Affiliated to Jiangnan University, Wuxi, China.Department of Infectious Disease, The First People's Hospital of Yancheng City, Yancheng, China.Department of Laboratory Medicine, The First People's Hospital of Yancheng City, Yancheng, China.Department of Infectious Disease, The Second People's Hospital of Yancheng City, Yancheng, China.Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.Department of Laboratory Medicine, The Second People's Hospital of Yancheng City, Yancheng, China.State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.Department of Laboratory Medicine, The Central Blood Station of Yancheng City, Yancheng, Jiangsu, China.State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. Zhejiang Provincial Key Laboratory for Diagnosis and Treatment of Aging and Physicochemical Injury Diseases, Hangzhou, China.State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

32109279

Citation

Wu, Jian, et al. "Clinical Characteristics of Imported Cases of Coronavirus Disease 2019 (COVID-19) in Jiangsu Province: a Multicenter Descriptive Study." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 71, no. 15, 2020, pp. 706-712.
Wu J, Liu J, Zhao X, et al. Clinical Characteristics of Imported Cases of Coronavirus Disease 2019 (COVID-19) in Jiangsu Province: A Multicenter Descriptive Study. Clin Infect Dis. 2020;71(15):706-712.
Wu, J., Liu, J., Zhao, X., Liu, C., Wang, W., Wang, D., Xu, W., Zhang, C., Yu, J., Jiang, B., Cao, H., & Li, L. (2020). Clinical Characteristics of Imported Cases of Coronavirus Disease 2019 (COVID-19) in Jiangsu Province: A Multicenter Descriptive Study. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 71(15), 706-712. https://doi.org/10.1093/cid/ciaa199
Wu J, et al. Clinical Characteristics of Imported Cases of Coronavirus Disease 2019 (COVID-19) in Jiangsu Province: a Multicenter Descriptive Study. Clin Infect Dis. 2020 07 28;71(15):706-712. PubMed PMID: 32109279.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical Characteristics of Imported Cases of Coronavirus Disease 2019 (COVID-19) in Jiangsu Province: A Multicenter Descriptive Study. AU - Wu,Jian, AU - Liu,Jun, AU - Zhao,Xinguo, AU - Liu,Chengyuan, AU - Wang,Wei, AU - Wang,Dawei, AU - Xu,Wei, AU - Zhang,Chunyu, AU - Yu,Jiong, AU - Jiang,Bin, AU - Cao,Hongcui, AU - Li,Lanjuan, PY - 2020/02/08/received PY - 2020/02/26/accepted PY - 2020/2/29/pubmed PY - 2020/8/11/medline PY - 2020/2/29/entrez KW - clinical characteristics KW - coronavirus disease 2019 (COVID-19) KW - imported cases KW - pneumonia SP - 706 EP - 712 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin Infect Dis VL - 71 IS - 15 N2 - BACKGROUND: We aimed to report the clinical characteristics of imported cases of coronavirus disease 2019 (COVID-19) in Jiangsu Province. METHODS: We retrospectively investigated the clinical, imaging, and laboratory characteristics of confirmed cases of COVID-19 with World Health Organization interim guidance in 3 grade IIIA hospitals of Jiangsu from 22 January to 14 February 2020. Real-time RT-PCR was used to detect the new coronavirus in respiratory samples. RESULTS: Of the 80 patients infected with COVID-19, 41 were female, with a median age of 46.1 years. Except for 3 severe patients, the rest of the 77 patients exhibited mild or moderate symptoms. Nine patients were unconfirmed until a third nucleic acid test; 38 cases had a history of chronic diseases. The main clinical manifestations of the patients were fever and cough, which accounted for 63 (78.75%) and 51 (63.75%) cases, respectively. Only 3 patients (3.75%) showed liver dysfunction. Imaging examination showed that 55 patients (68.75%) showed abnormal density shadow and 25 cases (31.25%) had no abnormal density shadow in the parenchyma of both lungs. Currently, 21 cases have been discharged from the hospital, and no patient died. The average length of stay for discharged patients was 8 days. CONCLUSIONS: Compared with the cases in Wuhan, the cases in Jiangsu exhibited mild or moderate symptoms and no obvious gender susceptibility. The proportion of patients having liver dysfunction and abnormal CT imaging was relatively lower than that in Wuhan. Notably, infected patients may be falsely excluded based on 2 consecutively negative respiratory pathogenic nucleic acid test results. SN - 1537-6591 UR - https://www.unboundmedicine.com/medline/citation/32109279/Clinical_Characteristics_of_Imported_Cases_of_Coronavirus_Disease_2019__COVID_19__in_Jiangsu_Province:_A_Multicenter_Descriptive_Study_ DB - PRIME DP - Unbound Medicine ER -