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[Characteristics of peripheral blood leukocyte differential counts in patients with COVID-19].
Zhonghua Nei Ke Za Zhi. 2020 Mar 01; 59(0):E003.ZN

Abstract

To investigate the early changes of peripheral blood leukocyte differential counts in patients with COVID-19. Ten patients with COVID-19 and 30 patients with other viral pneumonia (non-COVID-19) admitted to Shanghai Jiao Tong University Affiliated Sixth People's Hospital and Jinshan Branch Hospital from January 22 to February 17, 2020 were enrolled in this study. The differential counts of white blood cells were analyzed. Patients in COVID-19 group showed relatively lower absolute white blood cell (WBC) count 4.95(3.90,6.03)×10(9)/L, lymphocyte absolute count 1.20(0.98,1.50)×10(9)/L and eosinophil absolute count 0.01(0.01,0.01)×10(9)/L. Leukopenia developed in two patients(2/10), lymphocytopenia also in two patients(2/10). Seven over ten patients presented with eosinophil cytopenia. In non-COVID-19 group, absolute WBC count was 8.20 (6.78,9.03) ×10(9)/L (P<0.001), lymphocyte absolute count 1.75(1.20,2.53)×10(9)/L(P=0.036), eosinophil absolute count 0.02(0.01,0.03)×10(9)/L(P=0.05). Lymphocytopenia occurred in (16.7%) patients, eosinophil cytopenia in 16.7% patients too. In conclusion, leukopenia, lymphocytopenia and eosinophil cytopenia are more common in COVID-19 patients than those in non- COVID-19 patients.

Authors+Show Affiliations

Emergency Department, Shanghai Jiao Tong University Affiliated Sixth People's Hospital (The Sixth People's Hospital) , Shanghai200233, China.Emergency Department, Shanghai Jiao Tong University Affiliated Sixth People's Hospital (The Sixth People's Hospital) , Shanghai200233, China.Emergency Department, Jinshan Branch of The Sixth People's Hospital of Shanghai, Shanghai 201599, China.Emergency Department, Shanghai Jiao Tong University Affiliated Sixth People's Hospital (The Sixth People's Hospital) , Shanghai200233, China.Emergency Department, Shanghai Jiao Tong University Affiliated Sixth People's Hospital (The Sixth People's Hospital) , Shanghai200233, China.Emergency Department, Shanghai Jiao Tong University Affiliated Sixth People's Hospital (The Sixth People's Hospital) , Shanghai200233, China.Emergency Department, Shanghai Jiao Tong University Affiliated Sixth People's Hospital (The Sixth People's Hospital) , Shanghai200233, China.

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

32114745

Citation

Li, Y X., et al. "[Characteristics of Peripheral Blood Leukocyte Differential Counts in Patients With COVID-19]." Zhonghua Nei Ke Za Zhi, vol. 59, no. 0, 2020, pp. E003.
Li YX, Wu W, Yang T, et al. [Characteristics of peripheral blood leukocyte differential counts in patients with COVID-19]. Zhonghua Nei Ke Za Zhi. 2020;59(0):E003.
Li, Y. X., Wu, W., Yang, T., Zhou, W., Fu, Y. M., Feng, Q. M., & Ye, J. M. (2020). [Characteristics of peripheral blood leukocyte differential counts in patients with COVID-19]. Zhonghua Nei Ke Za Zhi, 59(0), E003. https://doi.org/3760.10/cma.j.cn112138-20200221-00114
Li YX, et al. [Characteristics of Peripheral Blood Leukocyte Differential Counts in Patients With COVID-19]. Zhonghua Nei Ke Za Zhi. 2020 Mar 1;59(0):E003. PubMed PMID: 32114745.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Characteristics of peripheral blood leukocyte differential counts in patients with COVID-19]. AU - Li,Y X, AU - Wu,W, AU - Yang,T, AU - Zhou,W, AU - Fu,Y M, AU - Feng,Q M, AU - Ye,J M, Y1 - 2020/03/01/ PY - 2020/3/3/entrez PY - 2020/3/3/pubmed PY - 2020/3/3/medline KW - COVID-19 KW - Eosinophil KW - Viral pneumonia SP - E003 EP - E003 JF - Zhonghua nei ke za zhi JO - Zhonghua Nei Ke Za Zhi VL - 59 IS - 0 N2 - To investigate the early changes of peripheral blood leukocyte differential counts in patients with COVID-19. Ten patients with COVID-19 and 30 patients with other viral pneumonia (non-COVID-19) admitted to Shanghai Jiao Tong University Affiliated Sixth People's Hospital and Jinshan Branch Hospital from January 22 to February 17, 2020 were enrolled in this study. The differential counts of white blood cells were analyzed. Patients in COVID-19 group showed relatively lower absolute white blood cell (WBC) count 4.95(3.90,6.03)×10(9)/L, lymphocyte absolute count 1.20(0.98,1.50)×10(9)/L and eosinophil absolute count 0.01(0.01,0.01)×10(9)/L. Leukopenia developed in two patients(2/10), lymphocytopenia also in two patients(2/10). Seven over ten patients presented with eosinophil cytopenia. In non-COVID-19 group, absolute WBC count was 8.20 (6.78,9.03) ×10(9)/L (P<0.001), lymphocyte absolute count 1.75(1.20,2.53)×10(9)/L(P=0.036), eosinophil absolute count 0.02(0.01,0.03)×10(9)/L(P=0.05). Lymphocytopenia occurred in (16.7%) patients, eosinophil cytopenia in 16.7% patients too. In conclusion, leukopenia, lymphocytopenia and eosinophil cytopenia are more common in COVID-19 patients than those in non- COVID-19 patients. SN - 0578-1426 UR - https://www.unboundmedicine.com/medline/citation/32114745/[Characteristics_of_peripheral_blood_leukocyte_differential_counts_in_patients_with_COVID_19]_ DB - PRIME DP - Unbound Medicine ER -
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