Tags

Type your tag names separated by a space and hit enter

Association Between Body Mass Index and Complications in Acoustic Neuroma Surgery.
Otolaryngol Head Neck Surg. 2020 Apr; 162(4):538-543.OH

Abstract

OBJECTIVES

Elevated body mass index (BMI) is a risk factor for surgical complications, but data in acoustic neuroma surgery are conflicting and limited to small single-institution studies. This work evaluates associations between BMI and complications in surgery for acoustic neuroma (AN).

STUDY DESIGN

Retrospective review.

SETTING

Two tertiary otology referral institutions.

SUBJECTS AND METHODS

Patients undergoing surgery for AN. Univariate and multivariate analysis of association between BMI and complications was performed using two-tailed t tests and binary logistic regression.

RESULTS

BMI ranged from 18.0 kg/m2 to 63.9 kg/m2 with mean of 29.2 kg/m2 among 362 included patients. High BMI was associated with increased risk of cerebrospinal fluid (CSF) leak (p = 0.003) and need for revision surgery within 6 months (p = 0.03). CSF leak occurred in 11.6% of obese patients (BMI ≥ 30.0) and 5.1% of patients with BMI < 30.0. There was no association between BMI and post-operative intracranial hemorrhage, wound infection, or incomplete resection (p > 0.05). Multivariate analysis revealed BMI was associated with CSF leak (odds ratio 1.11 per BMI point, p = 0.002) and need for revision surgery (odds ratio 1.07 per BMI point, p = 0.02) independent of age, gender, tumor size, or surgical approach.

CONCLUSIONS

The largest series to date investigating BMI in acoustic surgery is presented. Elevated BMI is strongly associated with CSF leak and need for revision surgery but not with other complications. Obese or overweight patients undergoing acoustic neuroma resection should be counseled of their increased risk of CSF leak.

Authors+Show Affiliations

Department of Surgery, Yale University School of Medicine, New Haven, CT, USA.Department of Neurotology, Michigan Ear Institute, Farmington Hills, MI, USA.Department of Otorhinolaryngology - Head and Neck Surgery, Rush University, Chicago, IL, USA.Department of Surgery, Yale University School of Medicine, New Haven, CT, USA.Department of Neurotology, Michigan Ear Institute, Farmington Hills, MI, USA.Department of Neurotology, Michigan Ear Institute, Farmington Hills, MI, USA.

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

32122225

Citation

Luryi, Alexander L., et al. "Association Between Body Mass Index and Complications in Acoustic Neuroma Surgery." Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, vol. 162, no. 4, 2020, pp. 538-543.
Luryi AL, Babu S, Michaelides EM, et al. Association Between Body Mass Index and Complications in Acoustic Neuroma Surgery. Otolaryngol Head Neck Surg. 2020;162(4):538-543.
Luryi, A. L., Babu, S., Michaelides, E. M., Kveton, J. F., Bojrab, D. I., & Schutt, C. A. (2020). Association Between Body Mass Index and Complications in Acoustic Neuroma Surgery. Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 162(4), 538-543. https://doi.org/10.1177/0194599820906400
Luryi AL, et al. Association Between Body Mass Index and Complications in Acoustic Neuroma Surgery. Otolaryngol Head Neck Surg. 2020;162(4):538-543. PubMed PMID: 32122225.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association Between Body Mass Index and Complications in Acoustic Neuroma Surgery. AU - Luryi,Alexander L, AU - Babu,Seilesh, AU - Michaelides,Elias M, AU - Kveton,John F, AU - Bojrab,Dennis I, AU - Schutt,Christopher A, Y1 - 2020/03/03/ PY - 2020/3/4/pubmed PY - 2020/7/3/medline PY - 2020/3/4/entrez KW - BMI KW - Neurotology KW - acoustic neuroma KW - cerebrospinal fluid leak KW - obesity SP - 538 EP - 543 JF - Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery JO - Otolaryngol Head Neck Surg VL - 162 IS - 4 N2 - OBJECTIVES: Elevated body mass index (BMI) is a risk factor for surgical complications, but data in acoustic neuroma surgery are conflicting and limited to small single-institution studies. This work evaluates associations between BMI and complications in surgery for acoustic neuroma (AN). STUDY DESIGN: Retrospective review. SETTING: Two tertiary otology referral institutions. SUBJECTS AND METHODS: Patients undergoing surgery for AN. Univariate and multivariate analysis of association between BMI and complications was performed using two-tailed t tests and binary logistic regression. RESULTS: BMI ranged from 18.0 kg/m2 to 63.9 kg/m2 with mean of 29.2 kg/m2 among 362 included patients. High BMI was associated with increased risk of cerebrospinal fluid (CSF) leak (p = 0.003) and need for revision surgery within 6 months (p = 0.03). CSF leak occurred in 11.6% of obese patients (BMI ≥ 30.0) and 5.1% of patients with BMI < 30.0. There was no association between BMI and post-operative intracranial hemorrhage, wound infection, or incomplete resection (p > 0.05). Multivariate analysis revealed BMI was associated with CSF leak (odds ratio 1.11 per BMI point, p = 0.002) and need for revision surgery (odds ratio 1.07 per BMI point, p = 0.02) independent of age, gender, tumor size, or surgical approach. CONCLUSIONS: The largest series to date investigating BMI in acoustic surgery is presented. Elevated BMI is strongly associated with CSF leak and need for revision surgery but not with other complications. Obese or overweight patients undergoing acoustic neuroma resection should be counseled of their increased risk of CSF leak. SN - 1097-6817 UR - https://www.unboundmedicine.com/medline/citation/32122225/Association_Between_Body_Mass_Index_and_Complications_in_Acoustic_Neuroma_Surgery L2 - http://journals.sagepub.com/doi/full/10.1177/0194599820906400?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -