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Specialties of hystomorphometrical changes in placenta of women with early and late preeclampsia.
Wiad Lek. 2020; 73(1):151-155.WL

Abstract

OBJECTIVE

The aim: To find out typical pathomorphological differences in placenta of women with early and late preeclampsia.

PATIENTS AND METHODS

Materials and methods: Investigation includes 40 placentas from deliveries in women with preeclampsia (main group) and 40 placentas from physiological delivery in somatically healthy women, who had no complications during pregnancy (control group). Placentas in the main group were devided into two sub-groups (20 in each) - with early and late preeclampsia. Specialties of the blood vessels in normal pregnancy were investigated, and their structural transformation with the developement of preeclampsia, according to the appearence of perinatal pathology. Morphometrical data of the blood stream was investigated with the help of eyepiece and program Image Tools 3,6.

RESULTS

Results: Significant decrease of weight (p<0,05), square and volume of placenta was common to early preeclampsia, comparing to the same characteristics in late Preeclampsia (PE). Specific gravity of villi without vessels, hardened blood vessels, hardened villi and fibrinoid altered vessels was increased statistically significantly (p<0,05) in placenta of women with early PE, comparing to women with late PE. The number of effective blood vessels crossings was determined mostly in late PE, comparing to the early form (p<0,05). Found out significant defferences (p<0,05) in changes of hystovasoarchitecture of placenta in early preeclampsia, according to the number of immature villi and villi with no signs of compensatory angiomatosis.

CONCLUSION

Conclusions: Increased number of hypoplasia of placenta, breach of effective placental blood stream and significant decrease of compensatory and adaptive changes in placenta are more common to early PE, comparing to late PE.

Authors+Show Affiliations

National Pirogov Memorial Medical University, Vinnytsia, Ukraine.National Pirogov Memorial Medical University, Vinnytsia, Ukraine.National Pirogov Memorial Medical University, Vinnytsia, Ukraine.National Pirogov Memorial Medical University, Vinnytsia, Ukraine.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32124826

Citation

Konkov, Dmitro G., et al. "Specialties of Hystomorphometrical Changes in Placenta of Women With Early and Late Preeclampsia." Wiadomosci Lekarskie (Warsaw, Poland : 1960), vol. 73, no. 1, 2020, pp. 151-155.
Konkov DG, Piskun AO, Taran OA, et al. Specialties of hystomorphometrical changes in placenta of women with early and late preeclampsia. Wiad Lek. 2020;73(1):151-155.
Konkov, D. G., Piskun, A. O., Taran, O. A., & Kostur, G. V. (2020). Specialties of hystomorphometrical changes in placenta of women with early and late preeclampsia. Wiadomosci Lekarskie (Warsaw, Poland : 1960), 73(1), 151-155.
Konkov DG, et al. Specialties of Hystomorphometrical Changes in Placenta of Women With Early and Late Preeclampsia. Wiad Lek. 2020;73(1):151-155. PubMed PMID: 32124826.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Specialties of hystomorphometrical changes in placenta of women with early and late preeclampsia. AU - Konkov,Dmitro G, AU - Piskun,Alina O, AU - Taran,Oksana A, AU - Kostur,Galyna V, PY - 2020/3/4/entrez PY - 2020/3/4/pubmed PY - 2020/3/4/medline KW - gestational endotheliosis KW - late preeclampsia KW - placenta SP - 151 EP - 155 JF - Wiadomosci lekarskie (Warsaw, Poland : 1960) JO - Wiad. Lek. VL - 73 IS - 1 N2 - OBJECTIVE: The aim: To find out typical pathomorphological differences in placenta of women with early and late preeclampsia. PATIENTS AND METHODS: Materials and methods: Investigation includes 40 placentas from deliveries in women with preeclampsia (main group) and 40 placentas from physiological delivery in somatically healthy women, who had no complications during pregnancy (control group). Placentas in the main group were devided into two sub-groups (20 in each) - with early and late preeclampsia. Specialties of the blood vessels in normal pregnancy were investigated, and their structural transformation with the developement of preeclampsia, according to the appearence of perinatal pathology. Morphometrical data of the blood stream was investigated with the help of eyepiece and program Image Tools 3,6. RESULTS: Results: Significant decrease of weight (p<0,05), square and volume of placenta was common to early preeclampsia, comparing to the same characteristics in late Preeclampsia (PE). Specific gravity of villi without vessels, hardened blood vessels, hardened villi and fibrinoid altered vessels was increased statistically significantly (p<0,05) in placenta of women with early PE, comparing to women with late PE. The number of effective blood vessels crossings was determined mostly in late PE, comparing to the early form (p<0,05). Found out significant defferences (p<0,05) in changes of hystovasoarchitecture of placenta in early preeclampsia, according to the number of immature villi and villi with no signs of compensatory angiomatosis. CONCLUSION: Conclusions: Increased number of hypoplasia of placenta, breach of effective placental blood stream and significant decrease of compensatory and adaptive changes in placenta are more common to early PE, comparing to late PE. SN - 0043-5147 UR - https://www.unboundmedicine.com/medline/citation/32124826/Specialties_of_hystomorphometrical_changes_in_placenta_of_women_with_early_and_late_preeclampsia DB - PRIME DP - Unbound Medicine ER -
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