Tags

Type your tag names separated by a space and hit enter

Epilepsia Partialis Continua as an Early Sign of Anti-Myelin Oligodendrocyte Glycoprotein Antibody-positive Encephalitis.
Intern Med. 2020 Jun 01; 59(11):1445-1449.IM

Abstract

Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have been associated with steroid-responsive cortical encephalitis and comorbid generalized epilepsy. A 44-year-old woman developed repeated epilepsia partialis continua (EPC) without generalized seizures and was anti-MOG antibody-positive. Radiological abnormalities were detected in the bilateral medial frontoparietal cortices, but there were no cerebrospinal fluid abnormalities. She achieved remission with anti-epileptic drugs alone. However, encephalitis recurred four months later when pleocytosis appeared, and steroid therapy was effective. Altogether, EPC without typical cerebrospinal fluid features can be an early sign of anti-MOG antibody-positive encephalitis. Thus, patients with EPC of unknown etiology need to be screened for anti-MOG antibodies.

Authors+Show Affiliations

Department of Neurology, Japanese Red Cross Medical Center, Japan.Department of Neurology, Japanese Red Cross Medical Center, Japan.Department of Neurology, Japanese Red Cross Medical Center, Japan.Department of Neurology, Japanese Red Cross Medical Center, Japan.Department of Neurosurgery, Japanese Red Cross Medical Center, Japan.Department of Neurosurgery, Japanese Red Cross Medical Center, Japan.Department of Neurosurgery, Japanese Red Cross Medical Center, Japan.Department of Neurosurgery, Japanese Red Cross Medical Center, Japan.Department of Neurology, Tohoku University Graduate School of Medicine, Japan. Department of Neurology, National Hospital Organization Yonezawa Hospital, Japan.Department of Neurology, Japanese Red Cross Medical Center, Japan.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

32132331

Citation

Katsuse, Kazuto, et al. "Epilepsia Partialis Continua as an Early Sign of Anti-Myelin Oligodendrocyte Glycoprotein Antibody-positive Encephalitis." Internal Medicine (Tokyo, Japan), vol. 59, no. 11, 2020, pp. 1445-1449.
Katsuse K, Shimizu G, Saito Sato N, et al. Epilepsia Partialis Continua as an Early Sign of Anti-Myelin Oligodendrocyte Glycoprotein Antibody-positive Encephalitis. Intern Med. 2020;59(11):1445-1449.
Katsuse, K., Shimizu, G., Saito Sato, N., Hatano, K., Yagi, S., Kimura, T., Irie, K., Ichi, S., Takahashi, T., & Hashida, H. (2020). Epilepsia Partialis Continua as an Early Sign of Anti-Myelin Oligodendrocyte Glycoprotein Antibody-positive Encephalitis. Internal Medicine (Tokyo, Japan), 59(11), 1445-1449. https://doi.org/10.2169/internalmedicine.3076-19
Katsuse K, et al. Epilepsia Partialis Continua as an Early Sign of Anti-Myelin Oligodendrocyte Glycoprotein Antibody-positive Encephalitis. Intern Med. 2020 Jun 1;59(11):1445-1449. PubMed PMID: 32132331.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epilepsia Partialis Continua as an Early Sign of Anti-Myelin Oligodendrocyte Glycoprotein Antibody-positive Encephalitis. AU - Katsuse,Kazuto, AU - Shimizu,Genki, AU - Saito Sato,Naoko, AU - Hatano,Keiko, AU - Yagi,Shintaro, AU - Kimura,Toshikazu, AU - Irie,Koreaki, AU - Ichi,Shunsuke, AU - Takahashi,Toshiyuki, AU - Hashida,Hideji, Y1 - 2020/03/05/ PY - 2020/3/7/pubmed PY - 2020/10/21/medline PY - 2020/3/6/entrez KW - anti-myelin oligodendrocyte glycoprotein (MOG) antibody KW - cortical encephalitis KW - epilepsia partialis continua (EPC) SP - 1445 EP - 1449 JF - Internal medicine (Tokyo, Japan) JO - Intern Med VL - 59 IS - 11 N2 - Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have been associated with steroid-responsive cortical encephalitis and comorbid generalized epilepsy. A 44-year-old woman developed repeated epilepsia partialis continua (EPC) without generalized seizures and was anti-MOG antibody-positive. Radiological abnormalities were detected in the bilateral medial frontoparietal cortices, but there were no cerebrospinal fluid abnormalities. She achieved remission with anti-epileptic drugs alone. However, encephalitis recurred four months later when pleocytosis appeared, and steroid therapy was effective. Altogether, EPC without typical cerebrospinal fluid features can be an early sign of anti-MOG antibody-positive encephalitis. Thus, patients with EPC of unknown etiology need to be screened for anti-MOG antibodies. SN - 1349-7235 UR - https://www.unboundmedicine.com/medline/citation/32132331/Epilepsia_Partialis_Continua_as_an_Early_Sign_of_Anti_Myelin_Oligodendrocyte_Glycoprotein_Antibody_positive_Encephalitis_ L2 - https://dx.doi.org/10.2169/internalmedicine.3076-19 DB - PRIME DP - Unbound Medicine ER -