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[Clinical features of 2019 novel coronavirus pneumonia in the early stage from a fever clinic in Beijing].
Zhonghua Jie He He Hu Xi Za Zhi. 2020 Mar 12; 43(3):215-218.ZJ

Abstract

Objective:

To summarize and analyze the clinical and imaging characteristics of patients with 2019 novel coronavirus pneumonia in the early stage in Beijing.

Methods:

A retrospective analysis of clinical and imaging data of 9 patients with 2019 novel coronavirus infection diagnosed in one fever clinicic in Beijing from January 18, 2020 to February 3, 2020.

Results:

5 male and 4 female was included in those 9 patients, whose median age was 36 years, and the age range from 15 to 49 years. 8 of these patients had no underlying disease and one suffered from diabetes. 7 patients had a history of travel to Wuhan City or Hubei Province, and one patient was a medical staff. Two family clustered was found. The incubation period was 1 to 6 days. The clinical manifestations were fever in 8 cases (8/9) , dry cough in 5 cases (5/9) , pharyngalgia in 4 cases (4/9) , fatigue in 4 cases (4/9) , body soreness in 4 cases (4/9) , and blocked or watery nose in 1 case (1/9) . Six patients (6/9) had abnormal cell peripheral blood, of which 3 (3/9) had an increased monocyte count, 2 (2/9) had a reduced lymphocyte, and 1 (1/9) had an increased leukocyte count, while the 3 patients had normal cell blood routines. The median of CRP was 16.3 mg/L, including 5 patients with slightly elevated (5/9) , 4 patients with normal values (4/9) . the results of procalcitonin test were negative in5 patients. Three patients were examined by chest X-ray examination, one of which was normal, one case showed infiltrates of right upper lung, and another showed in right lower lung. All patients underwent chest HRCT. And 7 cases (7/9) showed multiple ground glass exudation, including 5 cases (5/7) involved bilateral lungs, 2 cases (2/7) involved unilateral lung, 3 cases (3/7) with patchy consolidation, and 2 cases (2/9) showed no abnormality.

Conclusions:

The patents with 2019 novel coronavirus pneumonia in this study generally have an epidemiological history. The clinical manifestations are fever and cough. Peripheral white blood cell counts were most normal And PCT were all negative. Chest HRCT manifested as multiple ground-glass opacities with partly consolidation. Some patients had normal chest radiographs but HRCT showed pneumonia. Some patients had no pneumonia on chest HRCT.

Authors+Show Affiliations

Department of Respiratory Medicine, Peking University First Hospital, Beijing 100034, China.Department of kidney surgery, Peking University First Hospital, Beijing 100034, China.Department of kidney surgery, Peking University First Hospital, Beijing 100034, China.Department of Respiratory Medicine, Peking University First Hospital, Beijing 100034, China.Department of Respiratory Medicine, Peking University First Hospital, Beijing 100034, China.Department of Respiratory Medicine, Peking University First Hospital, Beijing 100034, China.Department of kidney surgery, Peking University First Hospital, Beijing 100034, China.Department of Respiratory Medicine, Peking University First Hospital, Beijing 100034, China.

Pub Type(s)

Journal Article

Language

chi

PubMed ID

32164091

Citation

Zhang, M Q., et al. "[Clinical Features of 2019 Novel Coronavirus Pneumonia in the Early Stage From a Fever Clinic in Beijing]." Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases, vol. 43, no. 3, 2020, pp. 215-218.
Zhang MQ, Wang XH, Chen YL, et al. [Clinical features of 2019 novel coronavirus pneumonia in the early stage from a fever clinic in Beijing]. Zhonghua Jie He He Hu Xi Za Zhi. 2020;43(3):215-218.
Zhang, M. Q., Wang, X. H., Chen, Y. L., Zhao, K. L., Cai, Y. Q., An, C. L., Lin, M. G., & Mu, X. D. (2020). [Clinical features of 2019 novel coronavirus pneumonia in the early stage from a fever clinic in Beijing]. Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases, 43(3), 215-218. https://doi.org/10.3760/cma.j.issn.1001-0939.2020.03.015
Zhang MQ, et al. [Clinical Features of 2019 Novel Coronavirus Pneumonia in the Early Stage From a Fever Clinic in Beijing]. Zhonghua Jie He He Hu Xi Za Zhi. 2020 Mar 12;43(3):215-218. PubMed PMID: 32164091.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical features of 2019 novel coronavirus pneumonia in the early stage from a fever clinic in Beijing]. AU - Zhang,M Q, AU - Wang,X H, AU - Chen,Y L, AU - Zhao,K L, AU - Cai,Y Q, AU - An,C L, AU - Lin,M G, AU - Mu,X D, PY - 2020/3/13/entrez PY - 2020/3/14/pubmed PY - 2020/3/21/medline KW - 2019 novel coronavirus KW - Clinical characteristics KW - Pneumonia SP - 215 EP - 218 JF - Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases JO - Zhonghua Jie He He Hu Xi Za Zhi VL - 43 IS - 3 N2 - Objective: To summarize and analyze the clinical and imaging characteristics of patients with 2019 novel coronavirus pneumonia in the early stage in Beijing. Methods: A retrospective analysis of clinical and imaging data of 9 patients with 2019 novel coronavirus infection diagnosed in one fever clinicic in Beijing from January 18, 2020 to February 3, 2020. Results: 5 male and 4 female was included in those 9 patients, whose median age was 36 years, and the age range from 15 to 49 years. 8 of these patients had no underlying disease and one suffered from diabetes. 7 patients had a history of travel to Wuhan City or Hubei Province, and one patient was a medical staff. Two family clustered was found. The incubation period was 1 to 6 days. The clinical manifestations were fever in 8 cases (8/9) , dry cough in 5 cases (5/9) , pharyngalgia in 4 cases (4/9) , fatigue in 4 cases (4/9) , body soreness in 4 cases (4/9) , and blocked or watery nose in 1 case (1/9) . Six patients (6/9) had abnormal cell peripheral blood, of which 3 (3/9) had an increased monocyte count, 2 (2/9) had a reduced lymphocyte, and 1 (1/9) had an increased leukocyte count, while the 3 patients had normal cell blood routines. The median of CRP was 16.3 mg/L, including 5 patients with slightly elevated (5/9) , 4 patients with normal values (4/9) . the results of procalcitonin test were negative in5 patients. Three patients were examined by chest X-ray examination, one of which was normal, one case showed infiltrates of right upper lung, and another showed in right lower lung. All patients underwent chest HRCT. And 7 cases (7/9) showed multiple ground glass exudation, including 5 cases (5/7) involved bilateral lungs, 2 cases (2/7) involved unilateral lung, 3 cases (3/7) with patchy consolidation, and 2 cases (2/9) showed no abnormality. Conclusions: The patents with 2019 novel coronavirus pneumonia in this study generally have an epidemiological history. The clinical manifestations are fever and cough. Peripheral white blood cell counts were most normal And PCT were all negative. Chest HRCT manifested as multiple ground-glass opacities with partly consolidation. Some patients had normal chest radiographs but HRCT showed pneumonia. Some patients had no pneumonia on chest HRCT. SN - 1001-0939 UR - https://www.unboundmedicine.com/medline/citation/32164091/[Clinical_features_of_2019_novel_coronavirus_pneumonia_in_the_early_stage_from_a_fever_clinic_in_Beijing]_ DB - PRIME DP - Unbound Medicine ER -