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Antioxidant Enzyme Activity and Lipid Peroxidation in Aporrectodea caliginosa Earthworms Exposed to Silver Nanoparticles and Silver Nitrate in Spiked Soil.
Environ Toxicol Chem. 2020 05; 39(6):1257-1266.ET

Abstract

Silver nanoparticles (AgNPs) from industrial use, discharged via the land application of sewage sludge, are interacting with soil biota, including earthworms. In affected organisms, excessive production of reactive oxygen species can result in lipid peroxidation, shifting the balance between oxidants and antioxidants to cause oxidative stress. We determined selected lower-tier biomarkers such as antioxidant responses and lipid peroxidation in Aporrectodea caliginosa earthworms exposed to soils spiked with AgNPs or silver nitrate (AgNO3). Aporrectodea caliginosa were exposed to AgNPs at 0 (control), 0.3, 3, 30, and 300 mg/kg or Ag+ (as AgNO3) at 0, 0.03, 0.3, 3, and 10 mg/kg in soil for 4 wk. At 1, 2, 3, and 4 wk, the activity of the antioxidant enzymes superoxide dismutase, catalase, glutathione peroxidase, glutathione S-transferase, as well as lipid peroxidation (malondialdehyde content), increased as a function of concentration, with a much larger response for Ag+ than AgNPs. Given the likelihood of ever-increasing AgNP concentrations in soil, where AgNPs can transform to ionic Ag (Ag+), our findings of antioxidant response to oxidative stress in a common indicator organism even at an environmentally realistic exposure concentration of 0.03 mg/kg demonstrate that AgNPs may affect soil fertility and, thus, agricultural production. Evaluating selected lower-tier biomarkers offers a meaningful assessment of AgNPs and Ag+ effects on terrestrial earthworms. Environ Toxicol Chem 2020;39:1257-1266. © 2020 SETAC.

Authors+Show Affiliations

Faculty of Agriculture and Life Sciences, Lincoln University, Lincoln, Canterbury, New Zealand.Faculty of Agriculture and Life Sciences, Lincoln University, Lincoln, Canterbury, New Zealand.Landcare Research, Lincoln, Canterbury, New Zealand.Faculty of Agriculture and Life Sciences, Lincoln University, Lincoln, Canterbury, New Zealand.Faculty of Agriculture and Life Sciences, Lincoln University, Lincoln, Canterbury, New Zealand.Faculty of Agriculture and Life Sciences, Lincoln University, Lincoln, Canterbury, New Zealand.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

32187710

Citation

Saleeb, Nadir, et al. "Antioxidant Enzyme Activity and Lipid Peroxidation in Aporrectodea Caliginosa Earthworms Exposed to Silver Nanoparticles and Silver Nitrate in Spiked Soil." Environmental Toxicology and Chemistry, vol. 39, no. 6, 2020, pp. 1257-1266.
Saleeb N, Robinson B, Cavanagh J, et al. Antioxidant Enzyme Activity and Lipid Peroxidation in Aporrectodea caliginosa Earthworms Exposed to Silver Nanoparticles and Silver Nitrate in Spiked Soil. Environ Toxicol Chem. 2020;39(6):1257-1266.
Saleeb, N., Robinson, B., Cavanagh, J., Ross, J., Munir, K., & Gooneratne, R. (2020). Antioxidant Enzyme Activity and Lipid Peroxidation in Aporrectodea caliginosa Earthworms Exposed to Silver Nanoparticles and Silver Nitrate in Spiked Soil. Environmental Toxicology and Chemistry, 39(6), 1257-1266. https://doi.org/10.1002/etc.4713
Saleeb N, et al. Antioxidant Enzyme Activity and Lipid Peroxidation in Aporrectodea Caliginosa Earthworms Exposed to Silver Nanoparticles and Silver Nitrate in Spiked Soil. Environ Toxicol Chem. 2020;39(6):1257-1266. PubMed PMID: 32187710.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant Enzyme Activity and Lipid Peroxidation in Aporrectodea caliginosa Earthworms Exposed to Silver Nanoparticles and Silver Nitrate in Spiked Soil. AU - Saleeb,Nadir, AU - Robinson,Brett, AU - Cavanagh,Jo, AU - Ross,James, AU - Munir,Kiran, AU - Gooneratne,Ravi, Y1 - 2020/05/07/ PY - 2019/04/06/received PY - 2019/04/30/revised PY - 2020/03/12/accepted PY - 2020/3/19/pubmed PY - 2020/12/22/medline PY - 2020/3/19/entrez KW - Biomarkers KW - Ecotoxicology KW - Emerging pollutants KW - Nanotoxicology KW - Silver nanoparticles KW - Silver nitrate SP - 1257 EP - 1266 JF - Environmental toxicology and chemistry JO - Environ Toxicol Chem VL - 39 IS - 6 N2 - Silver nanoparticles (AgNPs) from industrial use, discharged via the land application of sewage sludge, are interacting with soil biota, including earthworms. In affected organisms, excessive production of reactive oxygen species can result in lipid peroxidation, shifting the balance between oxidants and antioxidants to cause oxidative stress. We determined selected lower-tier biomarkers such as antioxidant responses and lipid peroxidation in Aporrectodea caliginosa earthworms exposed to soils spiked with AgNPs or silver nitrate (AgNO3). Aporrectodea caliginosa were exposed to AgNPs at 0 (control), 0.3, 3, 30, and 300 mg/kg or Ag+ (as AgNO3) at 0, 0.03, 0.3, 3, and 10 mg/kg in soil for 4 wk. At 1, 2, 3, and 4 wk, the activity of the antioxidant enzymes superoxide dismutase, catalase, glutathione peroxidase, glutathione S-transferase, as well as lipid peroxidation (malondialdehyde content), increased as a function of concentration, with a much larger response for Ag+ than AgNPs. Given the likelihood of ever-increasing AgNP concentrations in soil, where AgNPs can transform to ionic Ag (Ag+), our findings of antioxidant response to oxidative stress in a common indicator organism even at an environmentally realistic exposure concentration of 0.03 mg/kg demonstrate that AgNPs may affect soil fertility and, thus, agricultural production. Evaluating selected lower-tier biomarkers offers a meaningful assessment of AgNPs and Ag+ effects on terrestrial earthworms. Environ Toxicol Chem 2020;39:1257-1266. © 2020 SETAC. SN - 1552-8618 UR - https://www.unboundmedicine.com/medline/citation/32187710/Antioxidant_Enzyme_Activity_and_Lipid_Peroxidation_in_Aporrectodea_caliginosa_Earthworms_Exposed_to_Silver_Nanoparticles_and_Silver_Nitrate_in_Spiked_Soil_ L2 - https://doi.org/10.1002/etc.4713 DB - PRIME DP - Unbound Medicine ER -