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Association between motoric cognitive risk syndrome and frailty among older Chinese adults.
BMC Geriatr. 2020 03 19; 20(1):110.BG

Abstract

BACKGROUND

Motoric cognitive risk syndrome (MCR) is a newly proposed predementia syndrome incorporating subjective cognitive complaints and slow gait. Previous studies have reported that subjective cognitive complaints and slow gait are associated with frailty in cognitively unimpaired older adults, but little is known about the link between MCR and frailty in older adults. Therefore, the aim of the study was to explore the associations of MCR and its components with frailty in older Chinese adults.

METHODS

In an observational cross-sectional study, a total of 429 older adults aged 60 years and older were admitted to the geriatric department. According to MCR criteria, all participants were classified into 4 groups: 1) the MCR group; 2) the subjective cognitive complaints only group; 3) the slow gait only group; and 4) the healthy control group. Physical frailty was assessed by the Clinical Frailty Scale (CFS). Multivariate logistic regression analysis was used to examine the association between MCR and frailty in older adults.

RESULTS

The prevalence rates of subjective cognitive complaints, slow gait and MCR were 15.9, 10.0 and 4.0%, respectively. After adjusting for confounding variables, the logistic regression analysis showed that slow gait (odds ratio [OR]: 3.40, 95% confidence interval [CI]: 1.40-8.23, P = 0.007) and MCR (OR: 5.53, 95% CI: 1.46-20.89, P = 0.012) were independently associated with frailty, but subjective cognitive complaints were not.

CONCLUSIONS

MCR and slow gait were significantly associated with frailty in older Chinese adults. Further studies should prospectively determine the causal relationship between MCR and frailty.

Links

Authors+Show Affiliations

Department of Geriatric, Zhejiang Hospital, No. 12 Lingyin Road, Hangzhou, 310013, Zhejiang Province, China.

Department of Geriatric, Zhejiang Hospital, No. 12 Lingyin Road, Hangzhou, 310013, Zhejiang Province, China.

Department of Geriatric, Zhejiang Hospital, No. 12 Lingyin Road, Hangzhou, 310013, Zhejiang Province, China.

Department of Geriatric, Zhejiang Hospital, No. 12 Lingyin Road, Hangzhou, 310013, Zhejiang Province, China.

Department of Geriatric, Zhejiang Hospital, No. 12 Lingyin Road, Hangzhou, 310013, Zhejiang Province, China.

Department of Geriatric, Zhejiang Hospital, No. 12 Lingyin Road, Hangzhou, 310013, Zhejiang Province, China.

Department of Geriatric, Zhejiang Hospital, No. 12 Lingyin Road, Hangzhou, 310013, Zhejiang Province, China.

Department of Geriatric, Zhejiang Hospital, No. 12 Lingyin Road, Hangzhou, 310013, Zhejiang Province, China.

Department of Geriatric, Zhejiang Hospital, No. 12 Lingyin Road, Hangzhou, 310013, Zhejiang Province, China. lily197459@163.com.

MeSH

AgedAgingCognitionCognition DisordersCognitive DysfunctionCross-Sectional StudiesFemaleFrailtyGaitGeriatric AssessmentHumansMaleMiddle AgedMovement DisordersSyndrome

Pub Type(s)

Journal Article

Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

32192446

Citation

Shen, Shanshan, et al. "Association Between Motoric Cognitive Risk Syndrome and Frailty Among Older Chinese Adults." BMC Geriatrics, vol. 20, no. 1, 2020, p. 110.

Shen S, Zeng X, Xu L, et al. Association between motoric cognitive risk syndrome and frailty among older Chinese adults. BMC Geriatr. 2020;20(1):110.

Shen, S., Zeng, X., Xu, L., Chen, L., Liu, Z., Chu, J., Yang, Y., Wu, X., & Chen, X. (2020). Association between motoric cognitive risk syndrome and frailty among older Chinese adults. BMC Geriatrics, 20(1), 110. https://doi.org/10.1186/s12877-020-01511-0

Shen S, et al. Association Between Motoric Cognitive Risk Syndrome and Frailty Among Older Chinese Adults. BMC Geriatr. 2020 03 19;20(1):110. PubMed PMID: 32192446.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Association between motoric cognitive risk syndrome and frailty among older Chinese adults. AU - Shen,Shanshan, AU - Zeng,Xingkun, AU - Xu,Liyu, AU - Chen,Lingyan, AU - Liu,Zixia, AU - Chu,Jiaojiao, AU - Yang,Yinghong, AU - Wu,Xiushao, AU - Chen,Xujiao, Y1 - 2020/03/19/ PY - 2019/09/12/received PY - 2020/03/10/accepted PY - 2020/3/21/entrez PY - 2020/3/21/pubmed PY - 2020/12/1/medline KW - Cognitive complaints KW - Frailty KW - Older adult KW - Slow gait SP - 110 EP - 110 JF - BMC geriatrics JO - BMC Geriatr VL - 20 IS - 1 N2 - BACKGROUND: Motoric cognitive risk syndrome (MCR) is a newly proposed predementia syndrome incorporating subjective cognitive complaints and slow gait. Previous studies have reported that subjective cognitive complaints and slow gait are associated with frailty in cognitively unimpaired older adults, but little is known about the link between MCR and frailty in older adults. Therefore, the aim of the study was to explore the associations of MCR and its components with frailty in older Chinese adults. METHODS: In an observational cross-sectional study, a total of 429 older adults aged 60 years and older were admitted to the geriatric department. According to MCR criteria, all participants were classified into 4 groups: 1) the MCR group; 2) the subjective cognitive complaints only group; 3) the slow gait only group; and 4) the healthy control group. Physical frailty was assessed by the Clinical Frailty Scale (CFS). Multivariate logistic regression analysis was used to examine the association between MCR and frailty in older adults. RESULTS: The prevalence rates of subjective cognitive complaints, slow gait and MCR were 15.9, 10.0 and 4.0%, respectively. After adjusting for confounding variables, the logistic regression analysis showed that slow gait (odds ratio [OR]: 3.40, 95% confidence interval [CI]: 1.40-8.23, P = 0.007) and MCR (OR: 5.53, 95% CI: 1.46-20.89, P = 0.012) were independently associated with frailty, but subjective cognitive complaints were not. CONCLUSIONS: MCR and slow gait were significantly associated with frailty in older Chinese adults. Further studies should prospectively determine the causal relationship between MCR and frailty. SN - 1471-2318 UR - https://www.unboundmedicine.com/medline/citation/32192446/Association_between_motoric_cognitive_risk_syndrome_and_frailty_among_older_Chinese_adults_ DB - PRIME DP - Unbound Medicine ER -