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Autopsy in suspected COVID-19 cases.
J Clin Pathol. 2020 May; 73(5):239-242.JC

Abstract

The severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) outbreak in Wuhan, China has now spread to many countries across the world including the UK with an increasing death toll. This will inevitably lead to an increase in the number of suspected coronavirus disease 2019 (COVID-19)-related deaths at autopsy. The Royal College of Pathologists has responded to this concern with the release of a briefing on autopsy practice relating to COVID-19. The following article is a summary and interpretation of these guidelines. It includes a description of hazard group 3 organisms, the category to which SARS-CoV-2 has been assigned, a brief description of what is currently known about the pathological and autopsy findings in COVID-19, a summary of the recommendations for conducting autopsies in suspected COVID-19 cases and the techniques for making the diagnosis at autopsy. It concludes by considering the clinicopathological correlation and notification of such cases.

Authors+Show Affiliations

Department of Cellular Pathology, Imperial College London NHS Trust, London, UK brian.hanley1@nhs.net.Department of Histopathology, GKT, Medical school in London, London, UK.Department of Histopathology, Cwm Taf Morgannwg Health Board, Llantrisant, UK.Forensic Pathology Services, Oxon, UK.Department of Cellular Pathology, Imperial College London NHS Trust, London, UK.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32198191

Citation

Hanley, Brian, et al. "Autopsy in Suspected COVID-19 Cases." Journal of Clinical Pathology, vol. 73, no. 5, 2020, pp. 239-242.
Hanley B, Lucas SB, Youd E, et al. Autopsy in suspected COVID-19 cases. J Clin Pathol. 2020;73(5):239-242.
Hanley, B., Lucas, S. B., Youd, E., Swift, B., & Osborn, M. (2020). Autopsy in suspected COVID-19 cases. Journal of Clinical Pathology, 73(5), 239-242. https://doi.org/10.1136/jclinpath-2020-206522
Hanley B, et al. Autopsy in Suspected COVID-19 Cases. J Clin Pathol. 2020;73(5):239-242. PubMed PMID: 32198191.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Autopsy in suspected COVID-19 cases. AU - Hanley,Brian, AU - Lucas,Sebastian B, AU - Youd,Esther, AU - Swift,Benjamin, AU - Osborn,Michael, Y1 - 2020/03/20/ PY - 2020/03/09/received PY - 2020/03/11/accepted PY - 2020/3/22/pubmed PY - 2020/4/24/medline PY - 2020/3/22/entrez KW - autopsy pathology KW - diagnosis KW - lung KW - safety KW - virus SP - 239 EP - 242 JF - Journal of clinical pathology JO - J. Clin. Pathol. VL - 73 IS - 5 N2 - The severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) outbreak in Wuhan, China has now spread to many countries across the world including the UK with an increasing death toll. This will inevitably lead to an increase in the number of suspected coronavirus disease 2019 (COVID-19)-related deaths at autopsy. The Royal College of Pathologists has responded to this concern with the release of a briefing on autopsy practice relating to COVID-19. The following article is a summary and interpretation of these guidelines. It includes a description of hazard group 3 organisms, the category to which SARS-CoV-2 has been assigned, a brief description of what is currently known about the pathological and autopsy findings in COVID-19, a summary of the recommendations for conducting autopsies in suspected COVID-19 cases and the techniques for making the diagnosis at autopsy. It concludes by considering the clinicopathological correlation and notification of such cases. SN - 1472-4146 UR - https://www.unboundmedicine.com/medline/citation/32198191/full_citation L2 - http://jcp.bmj.com/cgi/pmidlookup?view=long&pmid=32198191 DB - PRIME DP - Unbound Medicine ER -