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Comparison of Patient-Oriented Eczema Measure and Patient-Oriented Scoring Atopic Dermatitis vs Eczema Area and Severity Index and other measures of atopic dermatitis: A validation study.
Ann Allergy Asthma Immunol. 2020 07; 125(1):78-83.AA

Abstract

BACKGROUND

Little is known about the measurement properties of Patient-Oriented Scoring Atopic Dermatitis (PO-SCORAD) in adults with atopic dermatitis (AD). Even less is known about how PO-SCORAD performs compared with the Patient-Oriented Eczema Measure (POEM).

OBJECTIVE

To examine the measurement properties of PO-SCORAD and compare them with those of POEM.

METHODS

A prospective dermatology practice-based study of 291 patients with AD (age range, 18-72 years).

RESULTS

PO-SCORAD and POEM were moderately correlated with each other (Spearman ρ = 0.56) and had weak-moderate correlations with the Numeric Rating Scale (NRS) worst itch and average itch, Dermatology Life Quality Index (DLQI), ItchyQOL, Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance (SD) and Sleep-Related Impairment (SRI), Patient Health Questionnaire-9 (PHQ-9), and Eczema Area and Severity Index (EASI) (P < .001). POEM had significantly stronger correlations with DLQI, ItchyQOL, and EASI than did PO-SCORAD. PO-SCORAD and POEM had fair discriminant validity. Changes from baseline in PO-SCORAD and POEM were moderately correlated with each other; were weakly to strongly correlated with NRS worst itch and average itch, DLQI, ItchyQOL, PROMIS SD, PROMIS SRI, PHQ-9, and EASI; and had good test-retest reliability. There was no differential item functioning of items or floor or ceiling effects for PO-SCORAD or POEM. The thresholds for meaningful change for PO-SCORAD and POEM were -15.5 and -5.0, respectively. Median completion times for PO-SCORAD and POEM were 3 minutes and 1 minute, respectively.

CONCLUSION

PO-SCORAD and POEM had good construct and cross-cultural validity, reliability, and responsiveness in adults with AD and were feasible for use in clinical trials and practice. However, POEM had better measurement properties than PO-SCORAD.

Authors+Show Affiliations

Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia. Electronic address: JonathanISilverberg@gmail.com.Department of Dermatology, Feinberg School of Medicine at Northwestern University, Chicago, Illinois.Department of Dermatology, Feinberg School of Medicine at Northwestern University, Chicago, Illinois.Department of Dermatology, Feinberg School of Medicine at Northwestern University, Chicago, Illinois.Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.State University of New York Downstate Medical Center, Brooklyn, New York.Galderma SA | Rx Strategy & Innovation Group, La Tour-de-Peliz, Switzerland.Galderma SA | Rx Strategy & Innovation Group, La Tour-de-Peliz, Switzerland.Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts.Department of Internal Medicine, Weiss Memorial Hospital, Chicago, Illinois.State University of New York Downstate Medical Center, Brooklyn, New York.Department of Dermatology, Feinberg School of Medicine at Northwestern University, Chicago, Illinois.

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Validation Study

Language

eng

PubMed ID

32199977

Citation

Silverberg, Jonathan I., et al. "Comparison of Patient-Oriented Eczema Measure and Patient-Oriented Scoring Atopic Dermatitis Vs Eczema Area and Severity Index and Other Measures of Atopic Dermatitis: a Validation Study." Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, vol. 125, no. 1, 2020, pp. 78-83.
Silverberg JI, Lei D, Yousaf M, et al. Comparison of Patient-Oriented Eczema Measure and Patient-Oriented Scoring Atopic Dermatitis vs Eczema Area and Severity Index and other measures of atopic dermatitis: A validation study. Ann Allergy Asthma Immunol. 2020;125(1):78-83.
Silverberg, J. I., Lei, D., Yousaf, M., Janmohamed, S. R., Vakharia, P. P., Chopra, R., Chavda, R., Gabriel, S., Patel, K. R., Singam, V., Kantor, R., & Hsu, D. Y. (2020). Comparison of Patient-Oriented Eczema Measure and Patient-Oriented Scoring Atopic Dermatitis vs Eczema Area and Severity Index and other measures of atopic dermatitis: A validation study. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, 125(1), 78-83. https://doi.org/10.1016/j.anai.2020.03.006
Silverberg JI, et al. Comparison of Patient-Oriented Eczema Measure and Patient-Oriented Scoring Atopic Dermatitis Vs Eczema Area and Severity Index and Other Measures of Atopic Dermatitis: a Validation Study. Ann Allergy Asthma Immunol. 2020;125(1):78-83. PubMed PMID: 32199977.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of Patient-Oriented Eczema Measure and Patient-Oriented Scoring Atopic Dermatitis vs Eczema Area and Severity Index and other measures of atopic dermatitis: A validation study. AU - Silverberg,Jonathan I, AU - Lei,Donald, AU - Yousaf,Muhammad, AU - Janmohamed,Sherief R, AU - Vakharia,Paras P, AU - Chopra,Rishi, AU - Chavda,Rajeev, AU - Gabriel,Sylvie, AU - Patel,Kevin R, AU - Singam,Vivek, AU - Kantor,Robert, AU - Hsu,Derek Y, Y1 - 2020/03/18/ PY - 2020/02/12/received PY - 2020/03/05/revised PY - 2020/03/09/accepted PY - 2020/3/23/pubmed PY - 2020/9/26/medline PY - 2020/3/23/entrez SP - 78 EP - 83 JF - Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology JO - Ann Allergy Asthma Immunol VL - 125 IS - 1 N2 - BACKGROUND: Little is known about the measurement properties of Patient-Oriented Scoring Atopic Dermatitis (PO-SCORAD) in adults with atopic dermatitis (AD). Even less is known about how PO-SCORAD performs compared with the Patient-Oriented Eczema Measure (POEM). OBJECTIVE: To examine the measurement properties of PO-SCORAD and compare them with those of POEM. METHODS: A prospective dermatology practice-based study of 291 patients with AD (age range, 18-72 years). RESULTS: PO-SCORAD and POEM were moderately correlated with each other (Spearman ρ = 0.56) and had weak-moderate correlations with the Numeric Rating Scale (NRS) worst itch and average itch, Dermatology Life Quality Index (DLQI), ItchyQOL, Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance (SD) and Sleep-Related Impairment (SRI), Patient Health Questionnaire-9 (PHQ-9), and Eczema Area and Severity Index (EASI) (P < .001). POEM had significantly stronger correlations with DLQI, ItchyQOL, and EASI than did PO-SCORAD. PO-SCORAD and POEM had fair discriminant validity. Changes from baseline in PO-SCORAD and POEM were moderately correlated with each other; were weakly to strongly correlated with NRS worst itch and average itch, DLQI, ItchyQOL, PROMIS SD, PROMIS SRI, PHQ-9, and EASI; and had good test-retest reliability. There was no differential item functioning of items or floor or ceiling effects for PO-SCORAD or POEM. The thresholds for meaningful change for PO-SCORAD and POEM were -15.5 and -5.0, respectively. Median completion times for PO-SCORAD and POEM were 3 minutes and 1 minute, respectively. CONCLUSION: PO-SCORAD and POEM had good construct and cross-cultural validity, reliability, and responsiveness in adults with AD and were feasible for use in clinical trials and practice. However, POEM had better measurement properties than PO-SCORAD. SN - 1534-4436 UR - https://www.unboundmedicine.com/medline/citation/32199977/Comparison_of_Patient_Oriented_Eczema_Measure_and_Patient_Oriented_Scoring_Atopic_Dermatitis_vs_Eczema_Area_and_Severity_Index_and_other_measures_of_atopic_dermatitis:_A_validation_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1081-1206(20)30150-2 DB - PRIME DP - Unbound Medicine ER -