Publisher Full Text
The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19.Emerg Microbes Infect. 2020 Dec; 9(1):707-713.EM
Abstract
This study aims to analyze the different clinical characteristics between children and their families infected with severe acute respiratory syndrome coronavirus 2. Clinical data from nine children and their 14 families were collected, including general status, clinical, laboratory test, and imaging characteristics. All the children were detected positive result after their families onset. Three children had fever (22.2%) or cough (11.2%) symptoms and six (66.7%) children had no symptom. Among the 14 adult patients, the major symptoms included fever (57.1%), cough (35.7%), chest tightness/pain (21.4%), fatigue (21.4%) and sore throat (7.1%). Nearly 70% of the patients had normal (71.4%) or decreased (28.6%) white blood cell counts, and 50% (7/14) had lymphocytopenia. There were 10 adults (71.4%) showed abnormal imaging. The main manifestations were pulmonary consolidation (70%), nodular shadow (50%), and ground glass opacity (50%). Five discharged children were admitted again because their stool showed positive result in SARS-CoV-2 PCR. COVID-19 in children is mainly caused by family transmission, and their symptoms are mild and prognosis is better than adult. However, their PCR result in stool showed longer time than their families. Because of the mild or asymptomatic clinical process, it is difficult to recognize early for pediatrician and public health staff.
Links
MeSH
Pub Type(s)
Comparative Study
Journal Article
Language
eng
PubMed ID
32208917
Citation
Su, Liang, et al. "The Different Clinical Characteristics of Corona Virus Disease Cases Between Children and Their Families in China - the Character of Children With COVID-19." Emerging Microbes & Infections, vol. 9, no. 1, 2020, pp. 707-713.
Su L, Ma X, Yu H, et al. The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19. Emerg Microbes Infect. 2020;9(1):707-713.
Su, L., Ma, X., Yu, H., Zhang, Z., Bian, P., Han, Y., Sun, J., Liu, Y., Yang, C., Geng, J., Zhang, Z., & Gai, Z. (2020). The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19. Emerging Microbes & Infections, 9(1), 707-713. https://doi.org/10.1080/22221751.2020.1744483
Su L, et al. The Different Clinical Characteristics of Corona Virus Disease Cases Between Children and Their Families in China - the Character of Children With COVID-19. Emerg Microbes Infect. 2020;9(1):707-713. PubMed PMID: 32208917.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19.
AU - Su,Liang,
AU - Ma,Xiang,
AU - Yu,Huafeng,
AU - Zhang,Zhaohua,
AU - Bian,Pengfei,
AU - Han,Yuling,
AU - Sun,Jing,
AU - Liu,Yanqin,
AU - Yang,Chun,
AU - Geng,Jin,
AU - Zhang,Zhongfa,
AU - Gai,Zhongtao,
PY - 2020/3/27/entrez
PY - 2020/3/27/pubmed
PY - 2020/4/9/medline
KW - Coronavirus
KW - children
KW - clinical characteristics
KW - corona virus diseases-19 (COVID-19)
KW - severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
SP - 707
EP - 713
JF - Emerging microbes & infections
JO - Emerg Microbes Infect
VL - 9
IS - 1
N2 - This study aims to analyze the different clinical characteristics between children and their families infected with severe acute respiratory syndrome coronavirus 2. Clinical data from nine children and their 14 families were collected, including general status, clinical, laboratory test, and imaging characteristics. All the children were detected positive result after their families onset. Three children had fever (22.2%) or cough (11.2%) symptoms and six (66.7%) children had no symptom. Among the 14 adult patients, the major symptoms included fever (57.1%), cough (35.7%), chest tightness/pain (21.4%), fatigue (21.4%) and sore throat (7.1%). Nearly 70% of the patients had normal (71.4%) or decreased (28.6%) white blood cell counts, and 50% (7/14) had lymphocytopenia. There were 10 adults (71.4%) showed abnormal imaging. The main manifestations were pulmonary consolidation (70%), nodular shadow (50%), and ground glass opacity (50%). Five discharged children were admitted again because their stool showed positive result in SARS-CoV-2 PCR. COVID-19 in children is mainly caused by family transmission, and their symptoms are mild and prognosis is better than adult. However, their PCR result in stool showed longer time than their families. Because of the mild or asymptomatic clinical process, it is difficult to recognize early for pediatrician and public health staff.
SN - 2222-1751
UR - https://www.unboundmedicine.com/medline/citation/32208917/The_different_clinical_characteristics_of_corona_virus_disease_cases_between_children_and_their_families_in_China___the_character_of_children_with_COVID_19_
L2 - https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1744483
DB - PRIME
DP - Unbound Medicine
ER -
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