Tags

Type your tag names separated by a space and hit enter

Colistin and tylosin enhances disaccharidase activities, and improves morphology and permeability of the intestine of broilers.
Br Poult Sci. 2020 Apr 20 [Online ahead of print]BP

Abstract

1. The present study focused on the potential effects of antibiotics on intestinal digestion and integrity in broilers in terms of disaccharidase activity, electrophysiological properties and morphology.2. One-day-old Arbour Acres birds were randomly allocated to one of four treatment groups for 42 days; control, colistin (20 mg/kg), tylosin (55 mg/kg) or chlortetracycline (CTC, 55 mg/kg) groups. Colistin and tylosin supplementation, but not CTC supplementation, caused an increase in body weight gain.3. Colistin and tylosin elevated the activities of maltase and sucrase in the mucosa of the jejunum on d 42. Age caused a gradual decrease in the short-circuit current (Isc) and conductance (Gt) of the ileum, as a measure of permeability. The Isc and Gt of the ileum were higher in the colistin-supplemented broilers than in the control birds on d 42. Tylosin- and CTC-supplemented birds displayed Isc and Gt values similar to those of the control birds.4. Colistin supplementation increased the villus area in the jejunum and thinned the muscularis mucosae in the ileum compared with the control group. Tylosin supplementation decreased the thickness of the muscularis mucosae and the depth of crypt in the jejunum. CTC thickened the muscularis mucosae in the jejunum and ileum.5. Colistin and tylosin exhibited a beneficial effect on intestinal digestion and integrity by enhancing disaccharidase activities and improving gut morphology and permeability.

Authors+Show Affiliations

Department of Nutrition, Livestock Research Institute, Council of Agriculture, Tainan City, Taiwan.Department of Animal Science and Technology, National Taiwan University; Taipei, Taiwan.Department of Animal Science and Technology, National Taiwan University; Taipei, Taiwan.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32216555

Citation

Hung, C C., et al. "Colistin and Tylosin Enhances Disaccharidase Activities, and Improves Morphology and Permeability of the Intestine of Broilers." British Poultry Science, 2020, pp. 1-6.
Hung CC, Chen CY, Chen BJ. Colistin and tylosin enhances disaccharidase activities, and improves morphology and permeability of the intestine of broilers. Br Poult Sci. 2020.
Hung, C. C., Chen, C. Y., & Chen, B. J. (2020). Colistin and tylosin enhances disaccharidase activities, and improves morphology and permeability of the intestine of broilers. British Poultry Science, 1-6. https://doi.org/10.1080/00071668.2020.1747598
Hung CC, Chen CY, Chen BJ. Colistin and Tylosin Enhances Disaccharidase Activities, and Improves Morphology and Permeability of the Intestine of Broilers. Br Poult Sci. 2020 Apr 20;1-6. PubMed PMID: 32216555.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Colistin and tylosin enhances disaccharidase activities, and improves morphology and permeability of the intestine of broilers. AU - Hung,C C, AU - Chen,C Y, AU - Chen,B J, Y1 - 2020/04/20/ PY - 2020/3/29/pubmed PY - 2020/3/29/medline PY - 2020/3/29/entrez KW - Antibiotics KW - broiler KW - disaccharidase KW - electrophysiological properties KW - intestinal morphology SP - 1 EP - 6 JF - British poultry science JO - Br. Poult. Sci. N2 - 1. The present study focused on the potential effects of antibiotics on intestinal digestion and integrity in broilers in terms of disaccharidase activity, electrophysiological properties and morphology.2. One-day-old Arbour Acres birds were randomly allocated to one of four treatment groups for 42 days; control, colistin (20 mg/kg), tylosin (55 mg/kg) or chlortetracycline (CTC, 55 mg/kg) groups. Colistin and tylosin supplementation, but not CTC supplementation, caused an increase in body weight gain.3. Colistin and tylosin elevated the activities of maltase and sucrase in the mucosa of the jejunum on d 42. Age caused a gradual decrease in the short-circuit current (Isc) and conductance (Gt) of the ileum, as a measure of permeability. The Isc and Gt of the ileum were higher in the colistin-supplemented broilers than in the control birds on d 42. Tylosin- and CTC-supplemented birds displayed Isc and Gt values similar to those of the control birds.4. Colistin supplementation increased the villus area in the jejunum and thinned the muscularis mucosae in the ileum compared with the control group. Tylosin supplementation decreased the thickness of the muscularis mucosae and the depth of crypt in the jejunum. CTC thickened the muscularis mucosae in the jejunum and ileum.5. Colistin and tylosin exhibited a beneficial effect on intestinal digestion and integrity by enhancing disaccharidase activities and improving gut morphology and permeability. SN - 1466-1799 UR - https://www.unboundmedicine.com/medline/citation/32216555/Colistin_and_tylosin_enhances_disaccharidase_activities,_and_improves_morphology_and_permeability_of_the_intestine_of_broilers L2 - http://www.tandfonline.com/doi/full/10.1080/00071668.2020.1747598 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.