Tags

Type your tag names separated by a space and hit enter

Changes in Nut Consumption and Subsequent Cardiovascular Disease Risk Among US Men and Women: 3 Large Prospective Cohort Studies.
J Am Heart Assoc. 2020 Apr 07; 9(7):e013877.JA

Abstract

Background We aim to evaluate the association of within-individual changes in consumption of total and specific types of nuts and the subsequent risk of incident cardiovascular disease (CVD) in US men and women. Methods and Results We included 34 103 men from the HPFS (Health Professionals Follow-Up Study) (1986-2012), 77 815 women from the NHS (Nurses' Health Study) (1986-2012), and 80 737 women from the NHS II (1991-2013). We assessed nut consumption every 4 years using validated food frequency questionnaires. We used multivariable Cox proportional hazards regression models to examine the association between 4-year changes in nut consumption and risk of confirmed CVD end points in the subsequent 4 years. Per 0.5 serving/day increase in total nut consumption was associated with lower risk of CVD (relative risk [RR], 0.92; 95% CI, 0.86-0.98), coronary heart disease (RR, 0.94; 95% CI, 0.89-0.99), and stroke (RR, 0.89; 95% CI, 0.83-0.95). Compared with individuals who remained nonconsumers in a 4-year interval, those who had higher consumption of total nuts (≥0.5 servings/day) had a lower risk of CVD (RR, 0.75; 95% CI, 0.67-0.84), coronary heart disease (RR, 0.80; 95% CI, 0.69-0.93), and stroke (RR, 0.68; 95% CI, 0.57-0.82) in next 4 years. Individuals who decreased nut consumption by ≥0.50 servings/day had a higher risk of developing CVD (RR, 1.14; 95% CI, 0.99-1.32), coronary heart disease (RR, 1.06; 95% CI, 0.88-1.28), and stroke (RR, 1.28; 95% CI, 1.02-1.60) when compared with those who maintained their nut consumption. Conclusions Increasing total consumption of nuts and intake of individual types of nuts (eg, walnuts, other tree nuts, and peanuts) was associated with a subsequent lower risk of CVD. These data support the role of nut intake in the primary prevention of CVD. Registration URL: http://www.clini​caltr​ials.gov. Unique identifiers: NCT00005152 and NCT00005182.

Authors+Show Affiliations

Department of Nutrition Harvard T.H. Chan School of Public Health Boston MA.Department of Nutrition Harvard T.H. Chan School of Public Health Boston MA. Channing Division of Network Medicine Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA.Department of Nutrition Harvard T.H. Chan School of Public Health Boston MA.Department of Nutrition Harvard T.H. Chan School of Public Health Boston MA. Division of Preventive Medicine Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA.Department of Nutrition Harvard T.H. Chan School of Public Health Boston MA. Channing Division of Network Medicine Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA.Division of Preventive Medicine Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA.Department of Nutrition Harvard T.H. Chan School of Public Health Boston MA. Channing Division of Network Medicine Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA.Department of Nutrition Harvard T.H. Chan School of Public Health Boston MA. Channing Division of Network Medicine Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA.Department of Nutrition Harvard T.H. Chan School of Public Health Boston MA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32233756

Citation

Liu, Xiaoran, et al. "Changes in Nut Consumption and Subsequent Cardiovascular Disease Risk Among US Men and Women: 3 Large Prospective Cohort Studies." Journal of the American Heart Association, vol. 9, no. 7, 2020, pp. e013877.
Liu X, Guasch-Ferré M, Drouin-Chartier JP, et al. Changes in Nut Consumption and Subsequent Cardiovascular Disease Risk Among US Men and Women: 3 Large Prospective Cohort Studies. J Am Heart Assoc. 2020;9(7):e013877.
Liu, X., Guasch-Ferré, M., Drouin-Chartier, J. P., Tobias, D. K., Bhupathiraju, S. N., Rexrode, K. M., Willett, W. C., Sun, Q., & Li, Y. (2020). Changes in Nut Consumption and Subsequent Cardiovascular Disease Risk Among US Men and Women: 3 Large Prospective Cohort Studies. Journal of the American Heart Association, 9(7), e013877. https://doi.org/10.1161/JAHA.119.013877
Liu X, et al. Changes in Nut Consumption and Subsequent Cardiovascular Disease Risk Among US Men and Women: 3 Large Prospective Cohort Studies. J Am Heart Assoc. 2020 Apr 7;9(7):e013877. PubMed PMID: 32233756.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Changes in Nut Consumption and Subsequent Cardiovascular Disease Risk Among US Men and Women: 3 Large Prospective Cohort Studies. AU - Liu,Xiaoran, AU - Guasch-Ferré,Marta, AU - Drouin-Chartier,Jean-Philippe, AU - Tobias,Deirdre K, AU - Bhupathiraju,Shilpa N, AU - Rexrode,Kathryn M, AU - Willett,Walter C, AU - Sun,Qi, AU - Li,Yanping, Y1 - 2020/04/01/ PY - 2020/4/3/entrez PY - 2020/4/3/pubmed PY - 2020/4/3/medline KW - cardiovascular disease KW - cohorts KW - nuts KW - peanuts KW - prevention KW - stroke SP - e013877 EP - e013877 JF - Journal of the American Heart Association JO - J Am Heart Assoc VL - 9 IS - 7 N2 - Background We aim to evaluate the association of within-individual changes in consumption of total and specific types of nuts and the subsequent risk of incident cardiovascular disease (CVD) in US men and women. Methods and Results We included 34 103 men from the HPFS (Health Professionals Follow-Up Study) (1986-2012), 77 815 women from the NHS (Nurses' Health Study) (1986-2012), and 80 737 women from the NHS II (1991-2013). We assessed nut consumption every 4 years using validated food frequency questionnaires. We used multivariable Cox proportional hazards regression models to examine the association between 4-year changes in nut consumption and risk of confirmed CVD end points in the subsequent 4 years. Per 0.5 serving/day increase in total nut consumption was associated with lower risk of CVD (relative risk [RR], 0.92; 95% CI, 0.86-0.98), coronary heart disease (RR, 0.94; 95% CI, 0.89-0.99), and stroke (RR, 0.89; 95% CI, 0.83-0.95). Compared with individuals who remained nonconsumers in a 4-year interval, those who had higher consumption of total nuts (≥0.5 servings/day) had a lower risk of CVD (RR, 0.75; 95% CI, 0.67-0.84), coronary heart disease (RR, 0.80; 95% CI, 0.69-0.93), and stroke (RR, 0.68; 95% CI, 0.57-0.82) in next 4 years. Individuals who decreased nut consumption by ≥0.50 servings/day had a higher risk of developing CVD (RR, 1.14; 95% CI, 0.99-1.32), coronary heart disease (RR, 1.06; 95% CI, 0.88-1.28), and stroke (RR, 1.28; 95% CI, 1.02-1.60) when compared with those who maintained their nut consumption. Conclusions Increasing total consumption of nuts and intake of individual types of nuts (eg, walnuts, other tree nuts, and peanuts) was associated with a subsequent lower risk of CVD. These data support the role of nut intake in the primary prevention of CVD. Registration URL: http://www.clini​caltr​ials.gov. Unique identifiers: NCT00005152 and NCT00005182. SN - 2047-9980 UR - https://www.unboundmedicine.com/medline/citation/32233756/Changes_in_Nut_Consumption_and_Subsequent_Cardiovascular_Disease_Risk_Among_US_Men_and_Women:_3_Large_Prospective_Cohort_Studies_ L2 - http://www.ahajournals.org/doi/full/10.1161/JAHA.119.013877?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.