Tags

Type your tag names separated by a space and hit enter

[Investigation of an epidemic cluster caused by COVID⁃19 cases in incubation period in Shanghai].
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Apr 01; 41(0):E033.ZL

Abstract

Objective:

To analyze the epidemiological characteristics of a cluster of 5 confirmed COVID⁃19 cases related with the transmission in incubation period of initial case, and find out the infection source and transmission chain..

Methods:

According to "The Prevention and Control Protocol for Coronavirus Disease 2019 (Third Edition)" issued by the National Health Commission, a field epidemiological survey was conducted for the 5 cases in January 2020. Nasopharyngeal swabs and sputum samples were collected from them for the detection of 2019-nCoV by real time RT-PCR. Multi prevention and control measures were taken, such as tracking and screening close contacts, medical isolation observation, investigating the epidemiological link, analyzing transmission chain.

Results:

Case 1, who had common environmental exposure with other COVID⁃19 cases, got sick on 20 January, 2020 and was confirmed on 1 February. Case 2 became symptomatic on 22 January and was confirmed on 27 January. Case 3 got sick on 25 January and was confirmed on 30 January. Case 4 had illness onset on 20 January and was confirmed on 1 February. Case 5 got sick on 23 January and was confirmed on 31 January. Among the 5 cases, case 2 died and the illness of other cases were effectively controlled. After exclusion of other common exposure factors, case 1 had a 6-hour meeting with case 2 and case 3 on 19 January. Case 2 and case 3 might be infected by case 1 during the incubation period. It is the key point for epidemiological investigation.

Conclusion:

The epidemiological investigation indicates that the transmission might occur in the incubation period of COVID-19 case, close attention should be paid to it in future COVID-19 prevention and control.

Authors+Show Affiliations

Institute of Infectious Disease Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.Department of Vector Biological Control, Huangpu District Center for Disease Control and Prevention, Shanghai 200000, China.Department of Acute Infectious Disease Prevention and Control, Baoshan District Center for Disease Control and Prevention, Shanghai 201900, China.Institute of Infectious Disease Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.Institute of Infectious Disease Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.Institute of Infectious Disease Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.Institute of Infectious Disease Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.Institute of Infectious Disease Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.Institute of Infectious Disease Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.Institute of Infectious Disease Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.Institute of Infectious Disease Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

32234128

Citation

Xiao, W J., et al. "[Investigation of an Epidemic Cluster Caused By COVID⁃19 Cases in Incubation Period in Shanghai]." Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, vol. 41, no. 0, 2020, pp. E033.
Xiao WJ, Gao Q, Jin K, et al. [Investigation of an epidemic cluster caused by COVID⁃19 cases in incubation period in Shanghai]. Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(0):E033.
Xiao, W. J., Gao, Q., Jin, K., Gong, X. H., Han, R. B., Jiang, C. Y., Jiang, X. J., Jin, B. H., Fang, Q. W., Pan, H., Wu, H. Y., & Sun, X. D. (2020). [Investigation of an epidemic cluster caused by COVID⁃19 cases in incubation period in Shanghai]. Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, 41(0), E033. https://doi.org/10.3760/cma.j.cn112338-20200302-00236
Xiao WJ, et al. [Investigation of an Epidemic Cluster Caused By COVID⁃19 Cases in Incubation Period in Shanghai]. Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Apr 1;41(0):E033. PubMed PMID: 32234128.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Investigation of an epidemic cluster caused by COVID⁃19 cases in incubation period in Shanghai]. AU - Xiao,W J, AU - Gao,Q, AU - Jin,K, AU - Gong,X H, AU - Han,R B, AU - Jiang,C Y, AU - Jiang,X J, AU - Jin,B H, AU - Fang,Q W, AU - Pan,H, AU - Wu,H Y, AU - Sun,X D, Y1 - 2020/04/01/ PY - 2020/4/3/entrez PY - 2020/4/3/pubmed PY - 2020/4/3/medline KW - COVID-19 KW - Epidemic cluster KW - Incubation period KW - Transmission SP - E033 EP - E033 JF - Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi JO - Zhonghua Liu Xing Bing Xue Za Zhi VL - 41 IS - 0 N2 - Objective: To analyze the epidemiological characteristics of a cluster of 5 confirmed COVID⁃19 cases related with the transmission in incubation period of initial case, and find out the infection source and transmission chain.. Methods: According to "The Prevention and Control Protocol for Coronavirus Disease 2019 (Third Edition)" issued by the National Health Commission, a field epidemiological survey was conducted for the 5 cases in January 2020. Nasopharyngeal swabs and sputum samples were collected from them for the detection of 2019-nCoV by real time RT-PCR. Multi prevention and control measures were taken, such as tracking and screening close contacts, medical isolation observation, investigating the epidemiological link, analyzing transmission chain. Results: Case 1, who had common environmental exposure with other COVID⁃19 cases, got sick on 20 January, 2020 and was confirmed on 1 February. Case 2 became symptomatic on 22 January and was confirmed on 27 January. Case 3 got sick on 25 January and was confirmed on 30 January. Case 4 had illness onset on 20 January and was confirmed on 1 February. Case 5 got sick on 23 January and was confirmed on 31 January. Among the 5 cases, case 2 died and the illness of other cases were effectively controlled. After exclusion of other common exposure factors, case 1 had a 6-hour meeting with case 2 and case 3 on 19 January. Case 2 and case 3 might be infected by case 1 during the incubation period. It is the key point for epidemiological investigation. Conclusion: The epidemiological investigation indicates that the transmission might occur in the incubation period of COVID-19 case, close attention should be paid to it in future COVID-19 prevention and control. SN - 0254-6450 UR - https://www.unboundmedicine.com/medline/citation/32234128/[Investigation_of_an_epidemic_cluster_caused_by_COVID⁃19_cases_in_incubation_period_in_Shanghai]_ DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.