TY - JOUR T1 - [Investigation of an epidemic cluster caused by COVID⁃19 cases in incubation period in Shanghai]. AU - Xiao,W J, AU - Gao,Q, AU - Jin,K, AU - Gong,X H, AU - Han,R B, AU - Jiang,C Y, AU - Jiang,X J, AU - Jin,B H, AU - Fang,Q W, AU - Pan,H, AU - Wu,H Y, AU - Sun,X D, Y1 - 2020/04/01/ PY - 2020/4/3/entrez PY - 2020/4/3/pubmed PY - 2020/4/3/medline KW - COVID-19 KW - Epidemic cluster KW - Incubation period KW - Transmission SP - E033 EP - E033 JF - Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi JO - Zhonghua Liu Xing Bing Xue Za Zhi VL - 41 IS - 0 N2 - Objective: To analyze the epidemiological characteristics of a cluster of 5 confirmed COVID⁃19 cases related with the transmission in incubation period of initial case, and find out the infection source and transmission chain.. Methods: According to "The Prevention and Control Protocol for Coronavirus Disease 2019 (Third Edition)" issued by the National Health Commission, a field epidemiological survey was conducted for the 5 cases in January 2020. Nasopharyngeal swabs and sputum samples were collected from them for the detection of 2019-nCoV by real time RT-PCR. Multi prevention and control measures were taken, such as tracking and screening close contacts, medical isolation observation, investigating the epidemiological link, analyzing transmission chain. Results: Case 1, who had common environmental exposure with other COVID⁃19 cases, got sick on 20 January, 2020 and was confirmed on 1 February. Case 2 became symptomatic on 22 January and was confirmed on 27 January. Case 3 got sick on 25 January and was confirmed on 30 January. Case 4 had illness onset on 20 January and was confirmed on 1 February. Case 5 got sick on 23 January and was confirmed on 31 January. Among the 5 cases, case 2 died and the illness of other cases were effectively controlled. After exclusion of other common exposure factors, case 1 had a 6-hour meeting with case 2 and case 3 on 19 January. Case 2 and case 3 might be infected by case 1 during the incubation period. It is the key point for epidemiological investigation. Conclusion: The epidemiological investigation indicates that the transmission might occur in the incubation period of COVID-19 case, close attention should be paid to it in future COVID-19 prevention and control. SN - 0254-6450 UR - https://www.unboundmedicine.com/medline/citation/32234128/[Investigation_of_an_epidemic_cluster_caused_by_COVID���19_cases_in_incubation_period_in_Shanghai]_ DB - PRIME DP - Unbound Medicine ER -