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[Inhibitory effect of CG-120 on the formation, growth and aggregation of calcium oxalate crystals in vitro].
Hinyokika Kiyo. 1988 Jun; 34(6):1073-6.HK

Abstract

The inhibitory effect of CG-120 on the formation, growth and aggregation of calcium oxalate (CaOx) crystals was estimated by the use of Coulter counter TA II in the whole urine system and seed crystal method. In the whole urine system, after determining the metastable limit, the formation and growth of calcium oxalate crystals precipitated in response to a load of sodium oxalate was measured. CG-120 had a strong inhibitory effect on the formation and growth above the concentration of 500 micrograms/ml. In the seeded crystal system, inhibitory activity of aggregation (Ia) and growth (Ig) were calculated from the change in the number and volume of crystals. Above 250 micrograms/ml, CG-120 inhibited the aggregation and growth of added CaOx monohydrate and dihydrate crystals. CG-120 therefore might be useful for treating the recurrent stone formers.

Authors+Show Affiliations

Department of Urology, Kanazawa Medical University.No affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

jpn

PubMed ID

3223452

Citation

Suzuki, K, and R Tsugawa. "[Inhibitory Effect of CG-120 On the Formation, Growth and Aggregation of Calcium Oxalate Crystals in Vitro]." Hinyokika Kiyo. Acta Urologica Japonica, vol. 34, no. 6, 1988, pp. 1073-6.
Suzuki K, Tsugawa R. [Inhibitory effect of CG-120 on the formation, growth and aggregation of calcium oxalate crystals in vitro]. Hinyokika Kiyo. 1988;34(6):1073-6.
Suzuki, K., & Tsugawa, R. (1988). [Inhibitory effect of CG-120 on the formation, growth and aggregation of calcium oxalate crystals in vitro]. Hinyokika Kiyo. Acta Urologica Japonica, 34(6), 1073-6.
Suzuki K, Tsugawa R. [Inhibitory Effect of CG-120 On the Formation, Growth and Aggregation of Calcium Oxalate Crystals in Vitro]. Hinyokika Kiyo. 1988;34(6):1073-6. PubMed PMID: 3223452.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Inhibitory effect of CG-120 on the formation, growth and aggregation of calcium oxalate crystals in vitro]. AU - Suzuki,K, AU - Tsugawa,R, PY - 1988/6/1/pubmed PY - 1988/6/1/medline PY - 1988/6/1/entrez SP - 1073 EP - 6 JF - Hinyokika kiyo. Acta urologica Japonica JO - Hinyokika Kiyo VL - 34 IS - 6 N2 - The inhibitory effect of CG-120 on the formation, growth and aggregation of calcium oxalate (CaOx) crystals was estimated by the use of Coulter counter TA II in the whole urine system and seed crystal method. In the whole urine system, after determining the metastable limit, the formation and growth of calcium oxalate crystals precipitated in response to a load of sodium oxalate was measured. CG-120 had a strong inhibitory effect on the formation and growth above the concentration of 500 micrograms/ml. In the seeded crystal system, inhibitory activity of aggregation (Ia) and growth (Ig) were calculated from the change in the number and volume of crystals. Above 250 micrograms/ml, CG-120 inhibited the aggregation and growth of added CaOx monohydrate and dihydrate crystals. CG-120 therefore might be useful for treating the recurrent stone formers. SN - 0018-1994 UR - https://www.unboundmedicine.com/medline/citation/3223452/[Inhibitory_effect_of_CG_120_on_the_formation_growth_and_aggregation_of_calcium_oxalate_crystals_in_vitro]_ L2 - https://repository.kulib.kyoto-u.ac.jp/dspace/handle/2433/119594 DB - PRIME DP - Unbound Medicine ER -