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Gastrointestinal and liver manifestations in patients with COVID-19.
J Chin Med Assoc. 2020 06; 83(6):521-523.JC

Abstract

As the outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread over the world, the World Health Organization has declared the outbreak of COVID-19 an international public health emergency. Besides typical respiratory symptoms and signs of COVID-19, digestive symptoms and liver injury have been frequently reported during the course of the disease. In this review, we summarized the recent studies reporting of gastrointestinal and liver manifestations during the course of COVID-19. Digestive symptoms, including anorexia, nausea, vomiting, and diarrhea, are not uncommon in patients with COVID-19, and in some cases digestive symptoms may occur in the absence of any respiratory symptoms. Furthermore, SARS-CoV-2 could be detected in the stool of infected patients, implicating the possibility of fecal-oral transmission. Attention should also be paid to monitor liver function during the course of COVID-19, especially in patients with higher disease severity.

Authors+Show Affiliations

Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC.Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. Institute of Pharmacology, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC.Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC. Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32243269

Citation

Lee, I-Cheng, et al. "Gastrointestinal and Liver Manifestations in Patients With COVID-19." Journal of the Chinese Medical Association : JCMA, vol. 83, no. 6, 2020, pp. 521-523.
Lee IC, Huo TI, Huang YH. Gastrointestinal and liver manifestations in patients with COVID-19. J Chin Med Assoc. 2020;83(6):521-523.
Lee, I. C., Huo, T. I., & Huang, Y. H. (2020). Gastrointestinal and liver manifestations in patients with COVID-19. Journal of the Chinese Medical Association : JCMA, 83(6), 521-523. https://doi.org/10.1097/JCMA.0000000000000319
Lee IC, Huo TI, Huang YH. Gastrointestinal and Liver Manifestations in Patients With COVID-19. J Chin Med Assoc. 2020;83(6):521-523. PubMed PMID: 32243269.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastrointestinal and liver manifestations in patients with COVID-19. AU - Lee,I-Cheng, AU - Huo,Teh-Ia, AU - Huang,Yi-Hsiang, PY - 2020/4/4/pubmed PY - 2020/6/17/medline PY - 2020/4/4/entrez SP - 521 EP - 523 JF - Journal of the Chinese Medical Association : JCMA JO - J Chin Med Assoc VL - 83 IS - 6 N2 - As the outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread over the world, the World Health Organization has declared the outbreak of COVID-19 an international public health emergency. Besides typical respiratory symptoms and signs of COVID-19, digestive symptoms and liver injury have been frequently reported during the course of the disease. In this review, we summarized the recent studies reporting of gastrointestinal and liver manifestations during the course of COVID-19. Digestive symptoms, including anorexia, nausea, vomiting, and diarrhea, are not uncommon in patients with COVID-19, and in some cases digestive symptoms may occur in the absence of any respiratory symptoms. Furthermore, SARS-CoV-2 could be detected in the stool of infected patients, implicating the possibility of fecal-oral transmission. Attention should also be paid to monitor liver function during the course of COVID-19, especially in patients with higher disease severity. SN - 1728-7731 UR - https://www.unboundmedicine.com/medline/citation/32243269/Gastrointestinal_and_liver_manifestations_in_patients_with_COVID_19_ L2 - https://Insights.ovid.com/pubmed?pmid=32243269 DB - PRIME DP - Unbound Medicine ER -