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Pituitary responses to synthetic luteinizing hormone-releasing hormone in thirty-four cases of amenorrhea or oligomenorrhea associated with galactorrhea.
Am J Obstet Gynecol. 1977 Apr 01; 127(7):723-8.AJ

Abstract

Pituitary responses to 100 mcg. of luteinizing hormone-releasing hormone (LH-RH) administered subcutaneously were studied in 34 cases of amenorrhea or anovulatory oligomenorrhea associated with galactorrhea. Twenty-six patients had pituitary prolactin-secreting tumors (group I); eight patients had a normal sella turcica and remission of the syndrome either spontaneously or after thyroid replacement therapy (group 2). Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) responses to LH-RH were variable in each group of patients, ranging from poor to exaggerated, and no statistically significant difference could be observed between the groups. A positive correlation was found between FSH pituitary responses and basal FSH levels (r=0.50; P less than 0.01). No positive correlation was observed between either LH responses and basal LH levels or the gonadotropin responses and plasma estradiol levels, serum prolactin concentrations, duration of amenorrhea, or size of the tumor.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

322489

Citation

van Campenhout, J, et al. "Pituitary Responses to Synthetic Luteinizing Hormone-releasing Hormone in Thirty-four Cases of Amenorrhea or Oligomenorrhea Associated With Galactorrhea." American Journal of Obstetrics and Gynecology, vol. 127, no. 7, 1977, pp. 723-8.
van Campenhout J, Papas S, Blanchet P, et al. Pituitary responses to synthetic luteinizing hormone-releasing hormone in thirty-four cases of amenorrhea or oligomenorrhea associated with galactorrhea. Am J Obstet Gynecol. 1977;127(7):723-8.
van Campenhout, J., Papas, S., Blanchet, P., Wyman, H., & Somma, M. (1977). Pituitary responses to synthetic luteinizing hormone-releasing hormone in thirty-four cases of amenorrhea or oligomenorrhea associated with galactorrhea. American Journal of Obstetrics and Gynecology, 127(7), 723-8.
van Campenhout J, et al. Pituitary Responses to Synthetic Luteinizing Hormone-releasing Hormone in Thirty-four Cases of Amenorrhea or Oligomenorrhea Associated With Galactorrhea. Am J Obstet Gynecol. 1977 Apr 1;127(7):723-8. PubMed PMID: 322489.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pituitary responses to synthetic luteinizing hormone-releasing hormone in thirty-four cases of amenorrhea or oligomenorrhea associated with galactorrhea. AU - van Campenhout,J, AU - Papas,S, AU - Blanchet,P, AU - Wyman,H, AU - Somma,M, PY - 1977/4/1/pubmed PY - 1977/4/1/medline PY - 1977/4/1/entrez SP - 723 EP - 8 JF - American journal of obstetrics and gynecology JO - Am J Obstet Gynecol VL - 127 IS - 7 N2 - Pituitary responses to 100 mcg. of luteinizing hormone-releasing hormone (LH-RH) administered subcutaneously were studied in 34 cases of amenorrhea or anovulatory oligomenorrhea associated with galactorrhea. Twenty-six patients had pituitary prolactin-secreting tumors (group I); eight patients had a normal sella turcica and remission of the syndrome either spontaneously or after thyroid replacement therapy (group 2). Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) responses to LH-RH were variable in each group of patients, ranging from poor to exaggerated, and no statistically significant difference could be observed between the groups. A positive correlation was found between FSH pituitary responses and basal FSH levels (r=0.50; P less than 0.01). No positive correlation was observed between either LH responses and basal LH levels or the gonadotropin responses and plasma estradiol levels, serum prolactin concentrations, duration of amenorrhea, or size of the tumor. SN - 0002-9378 UR - https://www.unboundmedicine.com/medline/citation/322489/Pituitary_responses_to_synthetic_luteinizing_hormone_releasing_hormone_in_thirty_four_cases_of_amenorrhea_or_oligomenorrhea_associated_with_galactorrhea_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0002-9378(77)90246-0 DB - PRIME DP - Unbound Medicine ER -