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Genetic polymorphism analysis of 23 STR loci in the Tujia population from Chongqing, Southwest China.
Int J Legal Med. 2021 May; 135(3):761-763.IJ

Abstract

To evaluate the applicability of 23 autosomal STR loci (D10S1248, D11S4463, D12ATA63, D14S1434, D17S1301, D18S853, D1GATA113, D1S1627, D6S1017, D20S1082, D20S482, D17S974, D22S1045, D1S1677, D2S1776, D2S441, D3S4529, D4S2408, D9S1122D5S2500, D6S474, D18S51, D9S2157) included in DNA Typer™ 25 Kit for individual identification and parentage testing, allele frequencies and forensic efficiency parameters were first obtained from healthy, unrelated 506 Chongqing Tujia individuals. A total of 1012 alleles were identified in 23 STR loci, and allele frequencies ranged from 0.001 to 0.5761. The combined power of discrimination (CPD) and the combined power of exclusion (CPE) of the 23 STR loci were 0.999999999999999999999753 and 0.99999967, respectively. These results suggested that 23 autosomal STR loci could be used as an effective tool for forensic application in Chongqing Tujia population. Comprehensive comparisons were conducted based on the analysis of genetic distance, principal component analysis (PCA), multidimensional scaling plot (MDS), and phylogenetic tree to explore the interpopulation genetic relationship. Our results revealed that Chongqing Tujia keeps the more relatively genetic similarity with Hunan Han, Hubei Tujia, and Sichuan Han, which could be interpreted by that those populations were originated from the same ethnic ancestor or genetic communication were happened in adjacent areas.

Authors+Show Affiliations

Department of Forensic Medicine, Faculty of Basic Medical Science, Chongqing Medical University, Chongqing, 400016, China.Institute of Forensic Science, Ministry of Public Security of China Beijing, Beijing, 100038, China.Institute of Forensic Science, Ministry of Public Security of China Beijing, Beijing, 100038, China.Institute of Forensic Science, Ministry of Public Security of China Beijing, Beijing, 100038, China.Department of Forensic Medicine, Faculty of Basic Medical Science, Chongqing Medical University, Chongqing, 400016, China. 100390@cqmu.edu.cn.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32249359

Citation

Zhang, Li, et al. "Genetic Polymorphism Analysis of 23 STR Loci in the Tujia Population From Chongqing, Southwest China." International Journal of Legal Medicine, vol. 135, no. 3, 2021, pp. 761-763.
Zhang L, Yang F, Bai X, et al. Genetic polymorphism analysis of 23 STR loci in the Tujia population from Chongqing, Southwest China. Int J Legal Med. 2021;135(3):761-763.
Zhang, L., Yang, F., Bai, X., Yao, Y., & Li, J. (2021). Genetic polymorphism analysis of 23 STR loci in the Tujia population from Chongqing, Southwest China. International Journal of Legal Medicine, 135(3), 761-763. https://doi.org/10.1007/s00414-020-02287-z
Zhang L, et al. Genetic Polymorphism Analysis of 23 STR Loci in the Tujia Population From Chongqing, Southwest China. Int J Legal Med. 2021;135(3):761-763. PubMed PMID: 32249359.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Genetic polymorphism analysis of 23 STR loci in the Tujia population from Chongqing, Southwest China. AU - Zhang,Li, AU - Yang,Fan, AU - Bai,Xue, AU - Yao,Yiren, AU - Li,Jianbo, Y1 - 2020/04/06/ PY - 2020/2/11/received PY - 2020/3/24/accepted PY - 2020/4/7/pubmed PY - 2021/6/29/medline PY - 2020/4/7/entrez KW - Chongqing Tujia KW - Evolutionary relationship KW - Genetic polymorphism KW - STR SP - 761 EP - 763 JF - International journal of legal medicine JO - Int J Legal Med VL - 135 IS - 3 N2 - To evaluate the applicability of 23 autosomal STR loci (D10S1248, D11S4463, D12ATA63, D14S1434, D17S1301, D18S853, D1GATA113, D1S1627, D6S1017, D20S1082, D20S482, D17S974, D22S1045, D1S1677, D2S1776, D2S441, D3S4529, D4S2408, D9S1122D5S2500, D6S474, D18S51, D9S2157) included in DNA Typer™ 25 Kit for individual identification and parentage testing, allele frequencies and forensic efficiency parameters were first obtained from healthy, unrelated 506 Chongqing Tujia individuals. A total of 1012 alleles were identified in 23 STR loci, and allele frequencies ranged from 0.001 to 0.5761. The combined power of discrimination (CPD) and the combined power of exclusion (CPE) of the 23 STR loci were 0.999999999999999999999753 and 0.99999967, respectively. These results suggested that 23 autosomal STR loci could be used as an effective tool for forensic application in Chongqing Tujia population. Comprehensive comparisons were conducted based on the analysis of genetic distance, principal component analysis (PCA), multidimensional scaling plot (MDS), and phylogenetic tree to explore the interpopulation genetic relationship. Our results revealed that Chongqing Tujia keeps the more relatively genetic similarity with Hunan Han, Hubei Tujia, and Sichuan Han, which could be interpreted by that those populations were originated from the same ethnic ancestor or genetic communication were happened in adjacent areas. SN - 1437-1596 UR - https://www.unboundmedicine.com/medline/citation/32249359/Genetic_polymorphism_analysis_of_23_STR_loci_in_the_Tujia_population_from_Chongqing_Southwest_China_ DB - PRIME DP - Unbound Medicine ER -