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Early Management of Acute Unilateral Vocal Fold Paralysis: Update of the Literature.
J Voice. 2020 Apr 03 [Online ahead of print]JV

Abstract

BACKGROUND

Unilateral vocal fold paralysis (UVFP) often leads to significant morbidity that may include dysphonia, swallowing problems and aspiration. The best timing for medialization procedures is still controversial. Published data suggest that early intracordal injection positively affects long-term outcomes.

OBJECTIVES

To critically review current literature in order to determine if early treatment of acute UVFP influences clinical outcomes of the patients.

TYPE OF REVIEW

Nonsystematic literature review.

METHODS

A literature review was performed, using the Pubmed database. All relevant articles published in English addressing the effect of early treatment in acute unilateral focal fold paralysis were analyzed. Twenty-six articles were included due to their scientific interest.

RESULTS

Published literature suggests that early intracordal injection in patients with UVFP reduces pulmonary infections, hospital length of stay and improves voice parameters. Also, patients who receive early intracordal injection seem to be less likely to undergo subsequent medialization thyroplasty.

CONCLUSIONS

Early intracordal injection should be offered to patients with newly diagnosed UVFP since it promotes a satisfactory position of the vocal fold and seems to improve clinical outcomes. More investigation, with long-term follow up data and treatment randomization, is necessary to develop clinical consensus for these patients.

Authors+Show Affiliations

Department of Otorhinolaryngology, Centro Hospitalar Universitário S. João, EPE, Porto, Portugal; Unit of Otorhinolaryngology-Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal. Electronic address: joana.antunesmarques@gmail.com.Department of Otorhinolaryngology, Rouen University Hospital, Rouen, Normandy, France.Department of Otorhinolaryngology, Rouen University Hospital, Rouen, Normandy, France; Laboratory of Anatomy, Rouen Faculty of Medicine, Rouen, Normandy, France.Department of Otorhinolaryngology, CHU de Liège, Liège, Belgium.Unit of Otorhinolaryngology-Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal; Research Group on Ventilatory Handicap (EA 3830 GRHV), University of Rouen, Normandy, France; University Hospital Federation SURFACE, Regenerative surgery in Head and Neck, Amiens, France.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32253078

Citation

Marques, Joana A S., et al. "Early Management of Acute Unilateral Vocal Fold Paralysis: Update of the Literature." Journal of Voice : Official Journal of the Voice Foundation, 2020.
Marques JAS, Marronnier A, Crampon F, et al. Early Management of Acute Unilateral Vocal Fold Paralysis: Update of the Literature. J Voice. 2020.
Marques, J. A. S., Marronnier, A., Crampon, F., Lagier, A., & Marie, J. P. (2020). Early Management of Acute Unilateral Vocal Fold Paralysis: Update of the Literature. Journal of Voice : Official Journal of the Voice Foundation. https://doi.org/10.1016/j.jvoice.2020.02.021
Marques JAS, et al. Early Management of Acute Unilateral Vocal Fold Paralysis: Update of the Literature. J Voice. 2020 Apr 3; PubMed PMID: 32253078.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Early Management of Acute Unilateral Vocal Fold Paralysis: Update of the Literature. AU - Marques,Joana A S, AU - Marronnier,Adrien, AU - Crampon,Frédéric, AU - Lagier,Aude, AU - Marie,Jean-Paul, Y1 - 2020/04/03/ PY - 2019/12/26/received PY - 2020/02/20/revised PY - 2020/02/20/accepted PY - 2020/4/8/entrez KW - Dysphonia KW - Injection KW - Laryngoplasty KW - Larynx KW - Paralysis KW - Review KW - Vocal cords JF - Journal of voice : official journal of the Voice Foundation JO - J Voice N2 - BACKGROUND: Unilateral vocal fold paralysis (UVFP) often leads to significant morbidity that may include dysphonia, swallowing problems and aspiration. The best timing for medialization procedures is still controversial. Published data suggest that early intracordal injection positively affects long-term outcomes. OBJECTIVES: To critically review current literature in order to determine if early treatment of acute UVFP influences clinical outcomes of the patients. TYPE OF REVIEW: Nonsystematic literature review. METHODS: A literature review was performed, using the Pubmed database. All relevant articles published in English addressing the effect of early treatment in acute unilateral focal fold paralysis were analyzed. Twenty-six articles were included due to their scientific interest. RESULTS: Published literature suggests that early intracordal injection in patients with UVFP reduces pulmonary infections, hospital length of stay and improves voice parameters. Also, patients who receive early intracordal injection seem to be less likely to undergo subsequent medialization thyroplasty. CONCLUSIONS: Early intracordal injection should be offered to patients with newly diagnosed UVFP since it promotes a satisfactory position of the vocal fold and seems to improve clinical outcomes. More investigation, with long-term follow up data and treatment randomization, is necessary to develop clinical consensus for these patients. SN - 1873-4588 UR - https://www.unboundmedicine.com/medline/citation/32253078/Early_Management_of_Acute_Unilateral_Vocal_Fold_Paralysis:_Update_of_the_Literature L2 - https://linkinghub.elsevier.com/retrieve/pii/S0892-1997(20)30073-4 DB - PRIME DP - Unbound Medicine ER -
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