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The role of angiotensin-converting enzyme 2 in coronaviruses/influenza viruses and cardiovascular disease.
Cardiovasc Res. 2020 Oct 01; 116(12):1932-1936.CR

Abstract

Angiotensin-converting enzyme 2 (ACE2) has emerged as a key regulator of the renin-angiotensin system in cardiovascular (CV) disease and plays a pivotal role in infections by coronaviruses and influenza viruses. The present review is primarily focused on the findings to indicate the role of ACE2 in the relationship of coronaviruses and influenza viruses to CV disease. It is postulated that the risk of coronavirus or influenza virus infection is high, at least partly due to high ACE2 expression in populations with a high CV risk. Coronavirus and influenza virus vaccine usage in high CV risk populations could be a potential strategy to prevent both CV disease and coronavirus/influenza virus infections.

Authors+Show Affiliations

Georgia Prevention Institute, Department of Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.Department of Epidemiology, School of Medicine, Jinan University, Guangzhou 510632, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32267499

Citation

Chen, Li, and Guang Hao. "The Role of Angiotensin-converting Enzyme 2 in Coronaviruses/influenza Viruses and Cardiovascular Disease." Cardiovascular Research, vol. 116, no. 12, 2020, pp. 1932-1936.
Chen L, Hao G. The role of angiotensin-converting enzyme 2 in coronaviruses/influenza viruses and cardiovascular disease. Cardiovasc Res. 2020;116(12):1932-1936.
Chen, L., & Hao, G. (2020). The role of angiotensin-converting enzyme 2 in coronaviruses/influenza viruses and cardiovascular disease. Cardiovascular Research, 116(12), 1932-1936. https://doi.org/10.1093/cvr/cvaa093
Chen L, Hao G. The Role of Angiotensin-converting Enzyme 2 in Coronaviruses/influenza Viruses and Cardiovascular Disease. Cardiovasc Res. 2020 Oct 1;116(12):1932-1936. PubMed PMID: 32267499.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The role of angiotensin-converting enzyme 2 in coronaviruses/influenza viruses and cardiovascular disease. AU - Chen,Li, AU - Hao,Guang, PY - 2020/03/13/received PY - 2020/03/23/revised PY - 2020/04/01/accepted PY - 2020/4/9/pubmed PY - 2020/4/9/medline PY - 2020/4/9/entrez KW - Angiotensin-converting enzyme 2 KW - Cardiovascular disease KW - Coronaviruses KW - Influenza viruses SP - 1932 EP - 1936 JF - Cardiovascular research JO - Cardiovasc. Res. VL - 116 IS - 12 N2 - Angiotensin-converting enzyme 2 (ACE2) has emerged as a key regulator of the renin-angiotensin system in cardiovascular (CV) disease and plays a pivotal role in infections by coronaviruses and influenza viruses. The present review is primarily focused on the findings to indicate the role of ACE2 in the relationship of coronaviruses and influenza viruses to CV disease. It is postulated that the risk of coronavirus or influenza virus infection is high, at least partly due to high ACE2 expression in populations with a high CV risk. Coronavirus and influenza virus vaccine usage in high CV risk populations could be a potential strategy to prevent both CV disease and coronavirus/influenza virus infections. SN - 1755-3245 UR - https://www.unboundmedicine.com/medline/citation/32267499/The_role_of_angiotensin_converting_enzyme_2_in_coronaviruses/influenza_viruses_and_cardiovascular_disease_ L2 - https://academic.oup.com/cardiovascres/article-lookup/doi/10.1093/cvr/cvaa093 DB - PRIME DP - Unbound Medicine ER -
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