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Granulomatous rosacea-like skin rash: extranodal Rosai-Dorfman disease.
Int J Clin Exp Pathol. 2020; 13(3):556-558.IJ

Abstract

We report a 38-year-old man who presented with bilateral conjunctival congestion, hoarseness, and progressively growing pruritic, infiltrated skin lesions that had first begun over the face and neck, and later spread to the trunk and the limbs in 4 months. The clinical appearance of the lesions mimics granulomatous rosacea, acne vulgaris, or pityrosporum folliculitis. Histopathologic examination of the lesions from the face and chest both revealed dense dermal nodular lymphohistiocytic infiltrates which were positive for CD68 and S-100, but negative for CD1a. A systemic work-up for him detected no lymphadenopathy or other systemic involvement. A diagnosis of extranodal Rosai-Dorfman disease was made, and the patient received systemic glucocorticoids, with considerable improvement after 4 months of therapy.

Authors+Show Affiliations

Department of Dermatology, First People's Hospital of Pinghu City Pinghu 314200, Zhejiang Province, China.Department of Dermatology, The Second Affiliated Hospital, Zhejiang University School of Medicine No. 88, Jiefang Rd., Hangzhou 310009, Zhejiang Province, China.Department of Dermatology, Zhejiang Hospital No. 12, Lingyin Rd., Hangzhou 310013, Zhejiang Province, China.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

32269695

Citation

Shen, Hong-Ping, et al. "Granulomatous Rosacea-like Skin Rash: Extranodal Rosai-Dorfman Disease." International Journal of Clinical and Experimental Pathology, vol. 13, no. 3, 2020, pp. 556-558.
Shen HP, Lu ZF, Zhu JW. Granulomatous rosacea-like skin rash: extranodal Rosai-Dorfman disease. Int J Clin Exp Pathol. 2020;13(3):556-558.
Shen, H. P., Lu, Z. F., & Zhu, J. W. (2020). Granulomatous rosacea-like skin rash: extranodal Rosai-Dorfman disease. International Journal of Clinical and Experimental Pathology, 13(3), 556-558.
Shen HP, Lu ZF, Zhu JW. Granulomatous Rosacea-like Skin Rash: Extranodal Rosai-Dorfman Disease. Int J Clin Exp Pathol. 2020;13(3):556-558. PubMed PMID: 32269695.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Granulomatous rosacea-like skin rash: extranodal Rosai-Dorfman disease. AU - Shen,Hong-Ping, AU - Lu,Zhong-Fa, AU - Zhu,Jian-Wei, Y1 - 2020/03/01/ PY - 2019/12/29/received PY - 2020/02/06/accepted PY - 2020/4/10/entrez PY - 2020/4/10/pubmed PY - 2020/4/10/medline KW - Rosai-Dorfman disease KW - extranodal SP - 556 EP - 558 JF - International journal of clinical and experimental pathology JO - Int J Clin Exp Pathol VL - 13 IS - 3 N2 - We report a 38-year-old man who presented with bilateral conjunctival congestion, hoarseness, and progressively growing pruritic, infiltrated skin lesions that had first begun over the face and neck, and later spread to the trunk and the limbs in 4 months. The clinical appearance of the lesions mimics granulomatous rosacea, acne vulgaris, or pityrosporum folliculitis. Histopathologic examination of the lesions from the face and chest both revealed dense dermal nodular lymphohistiocytic infiltrates which were positive for CD68 and S-100, but negative for CD1a. A systemic work-up for him detected no lymphadenopathy or other systemic involvement. A diagnosis of extranodal Rosai-Dorfman disease was made, and the patient received systemic glucocorticoids, with considerable improvement after 4 months of therapy. SN - 1936-2625 UR - https://www.unboundmedicine.com/medline/citation/32269695/Granulomatous_rosacea-like_skin_rash:_extranodal_Rosai-Dorfman_disease DB - PRIME DP - Unbound Medicine ER -
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