Citation
Xing, Yu-Han, et al. "Prolonged Viral Shedding in Feces of Pediatric Patients With Coronavirus Disease 2019." Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi, vol. 53, no. 3, 2020, pp. 473-480.
Xing YH, Ni W, Wu Q, et al. Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019. J Microbiol Immunol Infect. 2020;53(3):473-480.
Xing, Y. H., Ni, W., Wu, Q., Li, W. J., Li, G. J., Wang, W. D., Tong, J. N., Song, X. F., Wing-Kin Wong, G., & Xing, Q. S. (2020). Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019. Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi, 53(3), 473-480. https://doi.org/10.1016/j.jmii.2020.03.021
Xing YH, et al. Prolonged Viral Shedding in Feces of Pediatric Patients With Coronavirus Disease 2019. J Microbiol Immunol Infect. 2020;53(3):473-480. PubMed PMID: 32276848.
TY - JOUR
T1 - Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019.
AU - Xing,Yu-Han,
AU - Ni,Wei,
AU - Wu,Qin,
AU - Li,Wen-Jie,
AU - Li,Guo-Ju,
AU - Wang,Wen-Di,
AU - Tong,Jian-Ning,
AU - Song,Xiu-Feng,
AU - Wing-Kin Wong,Gary,
AU - Xing,Quan-Sheng,
Y1 - 2020/03/28/
PY - 2020/03/20/received
PY - 2020/03/24/revised
PY - 2020/03/25/accepted
PY - 2020/4/12/pubmed
PY - 2020/6/17/medline
PY - 2020/4/12/entrez
KW - COVID-19
KW - Fecal shedding
KW - Pediatric patient
KW - SARS-CoV-2
SP - 473
EP - 480
JF - Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
JO - J Microbiol Immunol Infect
VL - 53
IS - 3
N2 - OBJECTIVE: To determine the dynamic changes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory and fecal specimens in children with coronavirus disease 2019 (COVID-19). METHODS: From January 17, 2020 to February 23, 2020, three paediatric cases of COVID-19 were reported in Qingdao, Shandong Province, China. Epidemiological, clinical, laboratory, and radiological characteristics and treatment data were collected. Patients were followed up to March 10, 2020, and dynamic profiles of nucleic acid testing results in throat swabs and fecal specimens were closely monitored. RESULTS: Clearance of SARS-CoV-2 in respiratory tract occurred within two weeks after abatement of fever, whereas viral RNA remained detectable in stools of pediatric patients for longer than 4 weeks. Two children had fecal SARS-CoV-2 undetectable 20 days after throat swabs showing negative, while that of another child lagged behind for 8 days. CONCLUSIONS: SARS-CoV-2 may exist in children's gastrointestinal tract for a longer time than respiratory system. Persistent shedding of SARS-CoV-2 in stools of infected children raises the possibility that the virus might be transmitted through contaminated fomites. Massive efforts should be made at all levels to prevent spreading of the infection among children after reopening of kindergartens and schools.
SN - 1995-9133
UR - https://www.unboundmedicine.com/medline/citation/32276848/Prolonged_viral_shedding_in_feces_of_pediatric_patients_with_coronavirus_disease_2019_
L2 - https://linkinghub.elsevier.com/retrieve/pii/S1684-1182(20)30081-5
DB - PRIME
DP - Unbound Medicine
ER -