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Drug repositioning is an alternative for the treatment of coronavirus COVID-19.
Int J Antimicrob Agents. 2020 Jun; 55(6):105969.IJ

Abstract

Given the extreme importance of the current pandemic caused by COVID-19, and as scientists agree there is no identified pharmacological treatment, where possible, therapeutic alternatives are raised through drug repositioning. This paper presents a selection of studies involving drugs from different pharmaceutical classes with activity against SARS-CoV-2 and SARS-CoV, with the potential for use in the treatment of COVID-19 disease.

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Authors+Show Affiliations

Serafin MB
Universidade Federal de Santa Maria, Programa de Pós-graduacão em Ciências Farmacêuticas, Santa Maria, RS, Brasil.
Bottega A
Universidade Federal de Santa Maria, Programa de Pós-graduacão em Ciências Farmacêuticas, Santa Maria, RS, Brasil.
Foletto VS
Universidade Federal de Santa Maria, Programa de Pós-graduacão em Ciências Farmacêuticas, Santa Maria, RS, Brasil.
da Rosa TF
Universidade Federal de Santa Maria, Programa de Pós-graduacão em Ciências Farmacêuticas, Santa Maria, RS, Brasil.
Hörner A
Universidade Federal de Santa Maria, Pós-Graduação Mestrado Profissional em Ciências da Saúde.
Hörner R
Universidade Federal de Santa Maria, Programa de Pós-graduacão em Ciências Farmacêuticas, Santa Maria, RS, Brasil; Universidade Federal de Santa Maria, Departamento de Análises Clínicas e Toxicológicas, Santa Maria, RS, Brasil. Electronic address: rosmari.ufsm@gmail.com.

MeSH

Adenosine MonophosphateAlanineAntiviral AgentsBetacoronavirusCOVID-19ChloroquineCoronavirus InfectionsDrug RepositioningHumansHydroxychloroquinePandemicsPneumonia, ViralSARS-CoV-2TeicoplaninCOVID-19 Drug Treatment

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32278811

Citation

Serafin, Marissa B., et al. "Drug Repositioning Is an Alternative for the Treatment of Coronavirus COVID-19." International Journal of Antimicrobial Agents, vol. 55, no. 6, 2020, p. 105969.
Serafin MB, Bottega A, Foletto VS, et al. Drug repositioning is an alternative for the treatment of coronavirus COVID-19. Int J Antimicrob Agents. 2020;55(6):105969.
Serafin, M. B., Bottega, A., Foletto, V. S., da Rosa, T. F., Hörner, A., & Hörner, R. (2020). Drug repositioning is an alternative for the treatment of coronavirus COVID-19. International Journal of Antimicrobial Agents, 55(6), 105969. https://doi.org/10.1016/j.ijantimicag.2020.105969
Serafin MB, et al. Drug Repositioning Is an Alternative for the Treatment of Coronavirus COVID-19. Int J Antimicrob Agents. 2020;55(6):105969. PubMed PMID: 32278811.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Drug repositioning is an alternative for the treatment of coronavirus COVID-19. AU - Serafin,Marissa B, AU - Bottega,Angelita, AU - Foletto,Vitória S, AU - da Rosa,Taciéli F, AU - Hörner,Andreas, AU - Hörner,Rosmari, Y1 - 2020/04/09/ PY - 2020/3/19/received PY - 2020/3/30/revised PY - 2020/4/1/accepted PY - 2020/4/13/pubmed PY - 2020/6/17/medline PY - 2020/4/13/entrez KW - COVID-19 KW - Repositioning KW - SARS-CoV-2 SP - 105969 EP - 105969 JF - International journal of antimicrobial agents JO - Int J Antimicrob Agents VL - 55 IS - 6 N2 - Given the extreme importance of the current pandemic caused by COVID-19, and as scientists agree there is no identified pharmacological treatment, where possible, therapeutic alternatives are raised through drug repositioning. This paper presents a selection of studies involving drugs from different pharmaceutical classes with activity against SARS-CoV-2 and SARS-CoV, with the potential for use in the treatment of COVID-19 disease. SN - 1872-7913 UR - https://www.unboundmedicine.com/medline/citation/32278811/Drug_repositioning_is_an_alternative_for_the_treatment_of_coronavirus_COVID_19_ DB - PRIME DP - Unbound Medicine ER -