Tags

Type your tag names separated by a space and hit enter

Household transmission of SARS-CoV-2.
J Infect. 2020 07; 81(1):179-182.JI

Abstract

BACKGROUND

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an epidemic in China and many other countries. Many infected clusters have been found within familial households, but the data about secondary transmission among household contacts is limited.

METHODS

In this retrospective case series, we enrolled 85 patients infected with SARS-CoV-2 and their household members in Wuhan. Patients were confirmed infected with SARS-CoV-2 by real-time reverse transcription polymerase chain reaction (RT-PCR) assays on throat swabs. Epidemiological, clinical and laboratory data of the household members were collected.

RESULTS

There were 155 close contacts in total. 104 contacts received RT-PCR assays, with 47 (30%) positive cases and 57 (37%) negative cases. 51 (33%) cases did not received RT-PCR tests for they showed no symptoms of pneumonia during the 2 weeks of quarantine. The infection rate of close contacts was 38% for households with 1 contact, 50% for households with 2 contacts, and 31% for households with 3 contacts.

CONCLUSIONS

The rate of secondary transmission among household contacts of patients with SARS-CoV-2 infection was 30%. Our data provide insight into the rate of secondary transmission of SARS-CoV-2 in home.

Authors+Show Affiliations

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue 1277#, Wuhan 430022, China.Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue 1277#, Wuhan 430022, China.Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue 1277#, Wuhan 430022, China. Electronic address: zrg27@163.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32283139

Citation

Wang, Zhongliang, et al. "Household Transmission of SARS-CoV-2." The Journal of Infection, vol. 81, no. 1, 2020, pp. 179-182.
Wang Z, Ma W, Zheng X, et al. Household transmission of SARS-CoV-2. J Infect. 2020;81(1):179-182.
Wang, Z., Ma, W., Zheng, X., Wu, G., & Zhang, R. (2020). Household transmission of SARS-CoV-2. The Journal of Infection, 81(1), 179-182. https://doi.org/10.1016/j.jinf.2020.03.040
Wang Z, et al. Household Transmission of SARS-CoV-2. J Infect. 2020;81(1):179-182. PubMed PMID: 32283139.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Household transmission of SARS-CoV-2. AU - Wang,Zhongliang, AU - Ma,Wanli, AU - Zheng,Xin, AU - Wu,Gang, AU - Zhang,Ruiguang, Y1 - 2020/04/10/ PY - 2020/03/19/received PY - 2020/03/21/accepted PY - 2020/4/14/pubmed PY - 2020/6/27/medline PY - 2020/4/14/entrez KW - Household KW - SARS-CoV-2 KW - Transmission KW - Wuhan SP - 179 EP - 182 JF - The Journal of infection JO - J Infect VL - 81 IS - 1 N2 - BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an epidemic in China and many other countries. Many infected clusters have been found within familial households, but the data about secondary transmission among household contacts is limited. METHODS: In this retrospective case series, we enrolled 85 patients infected with SARS-CoV-2 and their household members in Wuhan. Patients were confirmed infected with SARS-CoV-2 by real-time reverse transcription polymerase chain reaction (RT-PCR) assays on throat swabs. Epidemiological, clinical and laboratory data of the household members were collected. RESULTS: There were 155 close contacts in total. 104 contacts received RT-PCR assays, with 47 (30%) positive cases and 57 (37%) negative cases. 51 (33%) cases did not received RT-PCR tests for they showed no symptoms of pneumonia during the 2 weeks of quarantine. The infection rate of close contacts was 38% for households with 1 contact, 50% for households with 2 contacts, and 31% for households with 3 contacts. CONCLUSIONS: The rate of secondary transmission among household contacts of patients with SARS-CoV-2 infection was 30%. Our data provide insight into the rate of secondary transmission of SARS-CoV-2 in home. SN - 1532-2742 UR - https://www.unboundmedicine.com/medline/citation/32283139/Household_transmission_of_SARS_CoV_2_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0163-4453(20)30169-9 DB - PRIME DP - Unbound Medicine ER -