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German recommendations for critically ill patients with COVID‑19.
Med Klin Intensivmed Notfmed. 2020 Apr 14 [Online ahead of print]MK

Abstract

Since December 2019, a novel coronavirus (severe acute respiratory syndrome-coronavirus 2, SARS-CoV-2) has rapidly spread around the world resulting in an acute respiratory illness pandemic. The majority of patients presents with mild symptoms of coronavirus disease 2019 (COVID-19). However, about 5% become critically ill and require intensive care treatment. Acute hypoxemic failure with severe dyspnea and an increased respiratory rate (>30/min) usually leads to ICU admission. At that point, bilateral pulmonary infiltrates are typically seen. Patients often develop a severe acute respiratory distress syndrome (ARDS). To date there is no specific treatment available-the main goal of supportive therapy is to ascertain adequate oxygenation. Early intubation and repeated prone positioning are key elements in treating hypoxemic COVID-19 patients. Strict adherence to basic infection control measures (including hand hygiene) and use of personal protection equipment (PPE) are essential in the care of patients. Procedures that lead to formation of aerosols should be avoided where possible and carried out with utmost precaution.

Authors+Show Affiliations

German Society of Medical Intensive Care and Emergency Medicine (Deutsche Gesellschaft für Internistische Intensivmedizin und Notfallmedizin [DGIIN]), Berlin, Germany. skluge@uke.de. German Interdisciplinary Association of Critical Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin [DIVI]), Berlin, Germany. skluge@uke.de. ARDS Network Germany, Berlin, Germany. skluge@uke.de. Department of Intensive Care, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany. skluge@uke.de.German Society of Medical Intensive Care and Emergency Medicine (Deutsche Gesellschaft für Internistische Intensivmedizin und Notfallmedizin [DGIIN]), Berlin, Germany. German Interdisciplinary Association of Critical Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin [DIVI]), Berlin, Germany. ARDS Network Germany, Berlin, Germany.German Respiratory Society (Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin [DGP]), Berlin, Germany. ARDS Network Germany, Berlin, Germany.German Society of Anaesthesiology and Intensive Care Medicine (Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin [DGAI]), Nürnberg, Germany. ARDS Network Germany, Berlin, Germany.German Interdisciplinary Association of Critical Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin [DIVI]), Berlin, Germany. German Society of Anaesthesiology and Intensive Care Medicine (Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin [DGAI]), Nürnberg, Germany. ARDS Network Germany, Berlin, Germany.German Society of Medical Intensive Care and Emergency Medicine (Deutsche Gesellschaft für Internistische Intensivmedizin und Notfallmedizin [DGIIN]), Berlin, Germany. German Interdisciplinary Association of Critical Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin [DIVI]), Berlin, Germany. ARDS Network Germany, Berlin, Germany.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32291505

Citation

Kluge, Stefan, et al. "German Recommendations for Critically Ill Patients With COVID‑19." Medizinische Klinik, Intensivmedizin Und Notfallmedizin, 2020.
Kluge S, Janssens U, Welte T, et al. German recommendations for critically ill patients with COVID‑19. Med Klin Intensivmed Notfmed. 2020.
Kluge, S., Janssens, U., Welte, T., Weber-Carstens, S., Marx, G., & Karagiannidis, C. (2020). German recommendations for critically ill patients with COVID‑19. Medizinische Klinik, Intensivmedizin Und Notfallmedizin. https://doi.org/10.1007/s00063-020-00689-w
Kluge S, et al. German Recommendations for Critically Ill Patients With COVID‑19. Med Klin Intensivmed Notfmed. 2020 Apr 14; PubMed PMID: 32291505.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - German recommendations for critically ill patients with COVID‑19. AU - Kluge,Stefan, AU - Janssens,Uwe, AU - Welte,Tobias, AU - Weber-Carstens,Steffen, AU - Marx,Gernot, AU - Karagiannidis,Christian, Y1 - 2020/04/14/ PY - 2020/4/16/entrez PY - 2020/4/16/pubmed PY - 2020/4/16/medline KW - ARDS KW - Acute respiratory failure KW - COVID-19 KW - Coronavirus KW - High-flow nasal cannula JF - Medizinische Klinik, Intensivmedizin und Notfallmedizin JO - Med Klin Intensivmed Notfmed N2 - Since December 2019, a novel coronavirus (severe acute respiratory syndrome-coronavirus 2, SARS-CoV-2) has rapidly spread around the world resulting in an acute respiratory illness pandemic. The majority of patients presents with mild symptoms of coronavirus disease 2019 (COVID-19). However, about 5% become critically ill and require intensive care treatment. Acute hypoxemic failure with severe dyspnea and an increased respiratory rate (>30/min) usually leads to ICU admission. At that point, bilateral pulmonary infiltrates are typically seen. Patients often develop a severe acute respiratory distress syndrome (ARDS). To date there is no specific treatment available-the main goal of supportive therapy is to ascertain adequate oxygenation. Early intubation and repeated prone positioning are key elements in treating hypoxemic COVID-19 patients. Strict adherence to basic infection control measures (including hand hygiene) and use of personal protection equipment (PPE) are essential in the care of patients. Procedures that lead to formation of aerosols should be avoided where possible and carried out with utmost precaution. SN - 2193-6226 UR - https://www.unboundmedicine.com/medline/citation/32291505/full_citation L2 - https://dx.doi.org/10.1007/s00063-020-00689-w DB - PRIME DP - Unbound Medicine ER -
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