Tags

Type your tag names separated by a space and hit enter

Economic Analysis of Exclusive Human Milk Diets for High-Risk Neonates, a Canadian Hospital Perspective.
Breastfeed Med. 2020 Jun; 15(6):377-386.BM

Abstract

Background:

There is increasing evidence that premature newborns and infants with low birth weight can benefit substantially from an exclusive human milk-based diet (EHMD), consisting of human milk supplemented with a pasteurized donor human milk-derived fortifier. However, compared with the standard infant diet, EHMD also represents a significant added cost to the hospital and/or health system, thereby raising important questions about the economic feasibility of incorporating EHMD into newborn care.

Design:

We conducted a cost analysis and estimated the potential cost savings to a Canadian tertiary hospital based on the attributable complications averted from EHMD among low-weight neonates. A meta-analysis was performed to derive input parameters. A probabilistic analysis was conducted to determine the probability that EHMD is cost saving and 95% confidence interval (CI) around our estimates.

Results:

Our findings show that providing EHMD to preterm infants under 750 g at birth and at the highest risk of developing major complications is likely to be cost saving in the amount of $107,567 (95% CI: -145,229 to 360,362) per year. Extending EHMD to higher weight classes may be economically feasible depending on the pricing of the human milk-derived fortifier and the baseline risk of complications in the hospital setting.

Conclusions:

This comprehensive study provides critical insight for hospital-based decision makers to evaluate the potential gains and uncertainties associated with improved nutritional care for neonatal patients.

Authors+Show Affiliations

Ottawa Hospital Research Institute, Ontario, Canada. School of Epidemiology and Public Health, University of Ottawa, Ontario, Canada.Ottawa Hospital Research Institute, Ontario, Canada. Division of Neonatology, The Ottawa Hospital General Campus, Ontario, Canada.Ottawa Hospital Research Institute, Ontario, Canada.Ottawa Hospital Research Institute, Ontario, Canada.Ottawa Hospital Research Institute, Ontario, Canada. Division of Neonatology, The Ottawa Hospital General Campus, Ontario, Canada.School of Epidemiology and Public Health, University of Ottawa, Ontario, Canada. Division of Neonatology, The Ottawa Hospital General Campus, Ontario, Canada.Ottawa Hospital Research Institute, Ontario, Canada. The Ottawa Hospital, Ontario, Canada. Faculty of Medicine, University of Ottawa, Ontario, Canada.Ottawa Hospital Research Institute, Ontario, Canada. School of Epidemiology and Public Health, University of Ottawa, Ontario, Canada.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32302511

Citation

van Katwyk, Sasha, et al. "Economic Analysis of Exclusive Human Milk Diets for High-Risk Neonates, a Canadian Hospital Perspective." Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine, vol. 15, no. 6, 2020, pp. 377-386.
van Katwyk S, Ferretti E, Kumar S, et al. Economic Analysis of Exclusive Human Milk Diets for High-Risk Neonates, a Canadian Hospital Perspective. Breastfeed Med. 2020;15(6):377-386.
van Katwyk, S., Ferretti, E., Kumar, S., Hutton, B., Harrold, J., Walker, M., Forster, A. J., & Thavorn, K. (2020). Economic Analysis of Exclusive Human Milk Diets for High-Risk Neonates, a Canadian Hospital Perspective. Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine, 15(6), 377-386. https://doi.org/10.1089/bfm.2019.0273
van Katwyk S, et al. Economic Analysis of Exclusive Human Milk Diets for High-Risk Neonates, a Canadian Hospital Perspective. Breastfeed Med. 2020;15(6):377-386. PubMed PMID: 32302511.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Economic Analysis of Exclusive Human Milk Diets for High-Risk Neonates, a Canadian Hospital Perspective. AU - van Katwyk,Sasha, AU - Ferretti,Emanuela, AU - Kumar,Srishti, AU - Hutton,Brian, AU - Harrold,JoAnn, AU - Walker,Mark, AU - Forster,Alan J, AU - Thavorn,Kednapa, Y1 - 2020/04/17/ PY - 2020/4/18/pubmed PY - 2020/4/18/medline PY - 2020/4/18/entrez KW - economic evaluation KW - exclusive human milk diet KW - high-risk neonates SP - 377 EP - 386 JF - Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine JO - Breastfeed Med VL - 15 IS - 6 N2 - Background: There is increasing evidence that premature newborns and infants with low birth weight can benefit substantially from an exclusive human milk-based diet (EHMD), consisting of human milk supplemented with a pasteurized donor human milk-derived fortifier. However, compared with the standard infant diet, EHMD also represents a significant added cost to the hospital and/or health system, thereby raising important questions about the economic feasibility of incorporating EHMD into newborn care. Design: We conducted a cost analysis and estimated the potential cost savings to a Canadian tertiary hospital based on the attributable complications averted from EHMD among low-weight neonates. A meta-analysis was performed to derive input parameters. A probabilistic analysis was conducted to determine the probability that EHMD is cost saving and 95% confidence interval (CI) around our estimates. Results: Our findings show that providing EHMD to preterm infants under 750 g at birth and at the highest risk of developing major complications is likely to be cost saving in the amount of $107,567 (95% CI: -145,229 to 360,362) per year. Extending EHMD to higher weight classes may be economically feasible depending on the pricing of the human milk-derived fortifier and the baseline risk of complications in the hospital setting. Conclusions: This comprehensive study provides critical insight for hospital-based decision makers to evaluate the potential gains and uncertainties associated with improved nutritional care for neonatal patients. SN - 1556-8342 UR - https://www.unboundmedicine.com/medline/citation/32302511/Economic_Analysis_of_Exclusive_Human_Milk_Diets_for_High-Risk_Neonates,_a_Canadian_Hospital_Perspective L2 - https://www.liebertpub.com/doi/10.1089/bfm.2019.0273?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.