Tags

Type your tag names separated by a space and hit enter

Risk factors for neonatal seizures: A case-control study in the province of Parma, Italy.
Epilepsy Behav. 2020 Jun; 107:107075.EB

Abstract

PURPOSE

The present study evaluated the risk factors for electroencephalographic (EEG)-confirmed seizures during the whole neonatal period in preterm and term neonates born in the province of Parma between January 2009 and December 2014.

METHODS

We selected as cases the infants that presented EEG-confirmed neonatal seizures (NS). Two population controls for each case were matched by gestational age (GA), sex, hospital, and period of birth. Information on the mother, the pregnancy, the labor and delivery, and the neonates were taken from the Emilia-Romagna Certificate of Delivery Assistance database and from hospital charts and ICD-9-CM codes.

RESULTS AND INTERPRETATION

In the 6-year period of this study, 22 patients were recorded with NS. The association between at least one pregnancy complication and at least one neonatal complication, a low Apgar score, the need for resuscitation at birth, intraventricular hemorrhages (IVH) grades II-IV for preterm, and acute perinatal asphyxia/hypoxic-ischemic encephalopathy (HIE) for term infants were all statistically significant among cases. Neonates presenting these risk factors are more prone to develop NS and have to be strictly monitored.

Authors+Show Affiliations

Child Neuropsychiatric Unit, Medicine & Surgery Department, University of Parma, Italy.Child Neuropsychiatric Unit, Medicine & Surgery Department, University of Parma, Italy.Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy.Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy.Child Neuropsychiatric Unit, Mother and Child Department, University-Hospital of Parma, Parma, Italy.Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy. Electronic address: ettore.beghi@marionegri.it.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32304988

Citation

Pisani, Francesco, et al. "Risk Factors for Neonatal Seizures: a Case-control Study in the Province of Parma, Italy." Epilepsy & Behavior : E&B, vol. 107, 2020, p. 107075.
Pisani F, Facini C, Bianchi E, et al. Risk factors for neonatal seizures: A case-control study in the province of Parma, Italy. Epilepsy Behav. 2020;107:107075.
Pisani, F., Facini, C., Bianchi, E., Giussani, G., Piccolo, B., & Beghi, E. (2020). Risk factors for neonatal seizures: A case-control study in the province of Parma, Italy. Epilepsy & Behavior : E&B, 107, 107075. https://doi.org/10.1016/j.yebeh.2020.107075
Pisani F, et al. Risk Factors for Neonatal Seizures: a Case-control Study in the Province of Parma, Italy. Epilepsy Behav. 2020;107:107075. PubMed PMID: 32304988.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk factors for neonatal seizures: A case-control study in the province of Parma, Italy. AU - Pisani,Francesco, AU - Facini,Carlotta, AU - Bianchi,Elisa, AU - Giussani,Giorgia, AU - Piccolo,Benedetta, AU - Beghi,Ettore, Y1 - 2020/04/15/ PY - 2020/02/11/received PY - 2020/03/25/revised PY - 2020/03/26/accepted PY - 2020/4/19/pubmed PY - 2020/4/19/medline PY - 2020/4/19/entrez KW - Neonatal EEG KW - Neonatal seizures KW - Risk factors SP - 107075 EP - 107075 JF - Epilepsy & behavior : E&B JO - Epilepsy Behav VL - 107 N2 - PURPOSE: The present study evaluated the risk factors for electroencephalographic (EEG)-confirmed seizures during the whole neonatal period in preterm and term neonates born in the province of Parma between January 2009 and December 2014. METHODS: We selected as cases the infants that presented EEG-confirmed neonatal seizures (NS). Two population controls for each case were matched by gestational age (GA), sex, hospital, and period of birth. Information on the mother, the pregnancy, the labor and delivery, and the neonates were taken from the Emilia-Romagna Certificate of Delivery Assistance database and from hospital charts and ICD-9-CM codes. RESULTS AND INTERPRETATION: In the 6-year period of this study, 22 patients were recorded with NS. The association between at least one pregnancy complication and at least one neonatal complication, a low Apgar score, the need for resuscitation at birth, intraventricular hemorrhages (IVH) grades II-IV for preterm, and acute perinatal asphyxia/hypoxic-ischemic encephalopathy (HIE) for term infants were all statistically significant among cases. Neonates presenting these risk factors are more prone to develop NS and have to be strictly monitored. SN - 1525-5069 UR - https://www.unboundmedicine.com/medline/citation/32304988/Risk_factors_for_neonatal_seizures:_A_case-control_study_in_the_province_of_Parma,_Italy L2 - https://linkinghub.elsevier.com/retrieve/pii/S1525-5050(20)30254-7 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.