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Factors influencing the dynamics of gonadotropin response following bolus infusion of luteinizing hormone-releasing factor in women with menstrual abnormalities.
Fertil Steril. 1977 May; 28(5):526-30.FS

Abstract

Thirty-five women with menstrual abnormalities were given 100 microng of luteinizing hormone-releasing hormone (LHRH) by bolus intravenous injection in an attempt to simplify and quantitate the usefulness of this test in clinical management. Peak and total gonadotropin responses are highly correlated. Peak and total LH are significantly related to basal LH but no similar relationship could be established for follicle-stimulating hormone (FSH). There is no association between gonadotropin response and prolactin levels or body weight. Basal estradiol levels are inversely related to FSH response but not to LH response. It is concluded that the use of an intravenous 100-microng bolus of LHRH is of little use as a clinical test for the gynecologic endocrine patient.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

323072

Citation

Cantor, B, et al. "Factors Influencing the Dynamics of Gonadotropin Response Following Bolus Infusion of Luteinizing Hormone-releasing Factor in Women With Menstrual Abnormalities." Fertility and Sterility, vol. 28, no. 5, 1977, pp. 526-30.
Cantor B, Kalra PS, Buhi WC, et al. Factors influencing the dynamics of gonadotropin response following bolus infusion of luteinizing hormone-releasing factor in women with menstrual abnormalities. Fertil Steril. 1977;28(5):526-30.
Cantor, B., Kalra, P. S., Buhi, W. C., Birk, S. A., & Spellacy, W. N. (1977). Factors influencing the dynamics of gonadotropin response following bolus infusion of luteinizing hormone-releasing factor in women with menstrual abnormalities. Fertility and Sterility, 28(5), 526-30.
Cantor B, et al. Factors Influencing the Dynamics of Gonadotropin Response Following Bolus Infusion of Luteinizing Hormone-releasing Factor in Women With Menstrual Abnormalities. Fertil Steril. 1977;28(5):526-30. PubMed PMID: 323072.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Factors influencing the dynamics of gonadotropin response following bolus infusion of luteinizing hormone-releasing factor in women with menstrual abnormalities. AU - Cantor,B, AU - Kalra,P S, AU - Buhi,W C, AU - Birk,S A, AU - Spellacy,W N, PY - 1977/5/1/pubmed PY - 1977/5/1/medline PY - 1977/5/1/entrez KW - Amenorrhea KW - Biology KW - Clinical Research KW - Diseases KW - Endocrine System KW - Estradiol--analysis KW - Estrogens KW - Evaluation KW - Examinations And Diagnoses KW - Follicle Stimulating Hormone--analysis KW - Gonadotropins KW - Gonadotropins, Pituitary KW - Hormones KW - Laboratory Examinations And Diagnoses KW - Laboratory Procedures KW - Luteinizing Hormone--analysis KW - Menstruation Disorders KW - Physiology KW - Pituitary Hormone Releasing Hormones KW - Pituitary Hormones KW - Prolactin--analysis KW - Research Methodology SP - 526 EP - 30 JF - Fertility and sterility JO - Fertil Steril VL - 28 IS - 5 N2 - Thirty-five women with menstrual abnormalities were given 100 microng of luteinizing hormone-releasing hormone (LHRH) by bolus intravenous injection in an attempt to simplify and quantitate the usefulness of this test in clinical management. Peak and total gonadotropin responses are highly correlated. Peak and total LH are significantly related to basal LH but no similar relationship could be established for follicle-stimulating hormone (FSH). There is no association between gonadotropin response and prolactin levels or body weight. Basal estradiol levels are inversely related to FSH response but not to LH response. It is concluded that the use of an intravenous 100-microng bolus of LHRH is of little use as a clinical test for the gynecologic endocrine patient. SN - 0015-0282 UR - https://www.unboundmedicine.com/medline/citation/323072/Factors_influencing_the_dynamics_of_gonadotropin_response_following_bolus_infusion_of_luteinizing_hormone_releasing_factor_in_women_with_menstrual_abnormalities_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0015-0282(16)42551-3 DB - PRIME DP - Unbound Medicine ER -