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Scientific research progress of COVID-19/SARS-CoV-2 in the first five months.
J Cell Mol Med. 2020 06; 24(12):6558-6570.JC

Abstract

A cluster of pneumonia (COVID-19) cases have been found in Wuhan China in late December, 2019, and subsequently, a novel coronavirus with a positive stranded RNA was identified to be the aetiological virus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2), which has a phylogenetic similarity to severe acute respiratory syndrome coronavirus (SARS-CoV). SARS-CoV-2 transmits mainly through droplets and close contact and the elder or people with chronic diseases are high-risk population. People affected by SARS-CoV-2 can be asymptomatic, which brings about more difficulties to control the transmission. COVID-19 has become pandemic rapidly after onset, and so far the infected people have been above 2 000 000 and more than 130 000 died worldwide according to COVID-19 situation dashboard of World Health Organization (https://covid19.who.int). Here, we summarized the current known knowledge regarding epidemiological, pathogenesis, pathology, clinical features, comorbidities and treatment of COVID-19/ SARS-CoV-2 as reference for the prevention and control COVID-19.

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Authors+Show Affiliations

Li H
Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Shanghai Xuhui District Central Hospital and Zhongshan-Xuhui Hospital, Zhongshan Hospital, Fudan University, Shanghai, China.
Liu Z
Department of Medicine, BestNovo (Beijing) Medical Technology Co., Ltd, Beijing, China.
Ge J
Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Shanghai Xuhui District Central Hospital and Zhongshan-Xuhui Hospital, Zhongshan Hospital, Fudan University, Shanghai, China.

MeSH

Adenosine MonophosphateAlanineAmidesAngiotensin-Converting Enzyme 2Angiotensin-Converting Enzyme InhibitorsAntiviral AgentsBetacoronavirusCOVID-19COVID-19 TestingCOVID-19 VaccinesClinical Laboratory TechniquesCoronavirus InfectionsDisease ProgressionGene Expression RegulationHost-Pathogen InteractionsHumansImmunization, PassivePandemicsPeptidyl-Dipeptidase APneumonia, ViralPyrazinesSARS-CoV-2Severity of Illness IndexSpike Glycoprotein, CoronavirusViral VaccinesCOVID-19 Serotherapy

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

32320516

Citation

Li, Hua, et al. "Scientific Research Progress of COVID-19/SARS-CoV-2 in the First Five Months." Journal of Cellular and Molecular Medicine, vol. 24, no. 12, 2020, pp. 6558-6570.
Li H, Liu Z, Ge J. Scientific research progress of COVID-19/SARS-CoV-2 in the first five months. J Cell Mol Med. 2020;24(12):6558-6570.
Li, H., Liu, Z., & Ge, J. (2020). Scientific research progress of COVID-19/SARS-CoV-2 in the first five months. Journal of Cellular and Molecular Medicine, 24(12), 6558-6570. https://doi.org/10.1111/jcmm.15364
Li H, Liu Z, Ge J. Scientific Research Progress of COVID-19/SARS-CoV-2 in the First Five Months. J Cell Mol Med. 2020;24(12):6558-6570. PubMed PMID: 32320516.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Scientific research progress of COVID-19/SARS-CoV-2 in the first five months. AU - Li,Hua, AU - Liu,Zhe, AU - Ge,Junbo, Y1 - 2020/05/07/ PY - 2020/04/15/received PY - 2020/04/19/revised PY - 2020/04/22/accepted PY - 2020/4/23/pubmed PY - 2020/7/1/medline PY - 2020/4/23/entrez SP - 6558 EP - 6570 JF - Journal of cellular and molecular medicine JO - J Cell Mol Med VL - 24 IS - 12 N2 - A cluster of pneumonia (COVID-19) cases have been found in Wuhan China in late December, 2019, and subsequently, a novel coronavirus with a positive stranded RNA was identified to be the aetiological virus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2), which has a phylogenetic similarity to severe acute respiratory syndrome coronavirus (SARS-CoV). SARS-CoV-2 transmits mainly through droplets and close contact and the elder or people with chronic diseases are high-risk population. People affected by SARS-CoV-2 can be asymptomatic, which brings about more difficulties to control the transmission. COVID-19 has become pandemic rapidly after onset, and so far the infected people have been above 2 000 000 and more than 130 000 died worldwide according to COVID-19 situation dashboard of World Health Organization (https://covid19.who.int). Here, we summarized the current known knowledge regarding epidemiological, pathogenesis, pathology, clinical features, comorbidities and treatment of COVID-19/ SARS-CoV-2 as reference for the prevention and control COVID-19. SN - 1582-4934 UR - https://www.unboundmedicine.com/medline/citation/32320516/Scientific_research_progress_of_COVID_19/SARS_CoV_2_in_the_first_five_months_ DB - PRIME DP - Unbound Medicine ER -