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Chest CT findings of COVID-19 pneumonia by duration of symptoms.
Eur J Radiol. 2020 Jun; 127:109009.EJ

Abstract

PURPOSE

To evaluate lung abnormalities on thin-section computed tomographic (CT) scans in patients with COVID-19 and correlate findings to duration of symptoms.

METHODS

In total, 348 CT scans in 112 patients were classified according to the time after the onset of the initial symptoms, namely stage-1 (0-4 days); stage-2 (5-9 days); stage-3 (10-14 days); stage-4 (15-21 days); stage-5 (22-28 days); and stage-6 (>28 days). Each lung lobe was evaluated for extent affected by ground-glass opacities (GGO), crazy-paving pattern and consolidation, in five categories of percentual severity. Summation of scores from all five lung lobes provided the total CT score (maximal CT score, 25).

RESULTS

The predominant patterns of lung abnormalities were GGOs, crazy-paving pattern, consolidation and linear opacities. The frequency of crazy-paving pattern, consolidation and linear opacities peaked at stage-3 (62.7 %), stage-4 (75.0 %) and stage-5 (83.1 %), respectively, and decreased thereafter. Total CT scores increased from stage-1 to stage-2 (2.8 ± 3.1, vs. 6.5 ± 4.6, respectively, P < 0.01), and thereafter remained high. The lower lobes were more inclined to be involved with higher CT scores except for stage-1. At stage-6 98.1 % of CT scans still showed abnormalities (CT score 7.5 ± 4.1).

CONCLUSION

Thin-section CT could provide semi-quantitative analysis of pulmonary damage severity. This disease changed rapidly at the early stage, then tended to be stable and lasted for a long time.

Authors+Show Affiliations

Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, PR China. Electronic address: dingxun0217@163.com.Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, PR China. Electronic address: xujia424@163.com.Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, PR China. Electronic address: zhoujunzn@126.com.Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, PR China. Electronic address: longqy2005@126.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32325282

Citation

Ding, Xun, et al. "Chest CT Findings of COVID-19 Pneumonia By Duration of Symptoms." European Journal of Radiology, vol. 127, 2020, p. 109009.
Ding X, Xu J, Zhou J, et al. Chest CT findings of COVID-19 pneumonia by duration of symptoms. Eur J Radiol. 2020;127:109009.
Ding, X., Xu, J., Zhou, J., & Long, Q. (2020). Chest CT findings of COVID-19 pneumonia by duration of symptoms. European Journal of Radiology, 127, 109009. https://doi.org/10.1016/j.ejrad.2020.109009
Ding X, et al. Chest CT Findings of COVID-19 Pneumonia By Duration of Symptoms. Eur J Radiol. 2020;127:109009. PubMed PMID: 32325282.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chest CT findings of COVID-19 pneumonia by duration of symptoms. AU - Ding,Xun, AU - Xu,Jia, AU - Zhou,Jun, AU - Long,Qingyun, Y1 - 2020/04/18/ PY - 2020/03/25/received PY - 2020/04/05/revised PY - 2020/04/08/accepted PY - 2020/4/24/pubmed PY - 2020/5/16/medline PY - 2020/4/24/entrez KW - COVID-19 KW - Computed tomographic KW - Crazy-paving pattern KW - Ground-glass opacities SP - 109009 EP - 109009 JF - European journal of radiology JO - Eur J Radiol VL - 127 N2 - PURPOSE: To evaluate lung abnormalities on thin-section computed tomographic (CT) scans in patients with COVID-19 and correlate findings to duration of symptoms. METHODS: In total, 348 CT scans in 112 patients were classified according to the time after the onset of the initial symptoms, namely stage-1 (0-4 days); stage-2 (5-9 days); stage-3 (10-14 days); stage-4 (15-21 days); stage-5 (22-28 days); and stage-6 (>28 days). Each lung lobe was evaluated for extent affected by ground-glass opacities (GGO), crazy-paving pattern and consolidation, in five categories of percentual severity. Summation of scores from all five lung lobes provided the total CT score (maximal CT score, 25). RESULTS: The predominant patterns of lung abnormalities were GGOs, crazy-paving pattern, consolidation and linear opacities. The frequency of crazy-paving pattern, consolidation and linear opacities peaked at stage-3 (62.7 %), stage-4 (75.0 %) and stage-5 (83.1 %), respectively, and decreased thereafter. Total CT scores increased from stage-1 to stage-2 (2.8 ± 3.1, vs. 6.5 ± 4.6, respectively, P < 0.01), and thereafter remained high. The lower lobes were more inclined to be involved with higher CT scores except for stage-1. At stage-6 98.1 % of CT scans still showed abnormalities (CT score 7.5 ± 4.1). CONCLUSION: Thin-section CT could provide semi-quantitative analysis of pulmonary damage severity. This disease changed rapidly at the early stage, then tended to be stable and lasted for a long time. SN - 1872-7727 UR - https://www.unboundmedicine.com/medline/citation/32325282/Chest_CT_findings_of_COVID_19_pneumonia_by_duration_of_symptoms_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0720-048X(20)30198-4 DB - PRIME DP - Unbound Medicine ER -