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Neurological complications of coronavirus and COVID-19.
Rev Neurol. 2020 05 01; 70(9):311-322.RN

Abstract

INTRODUCTION

Clinical and experimental studies have shown that the coronavirus family has a certain tropism for the central nervous system. Seven types of coronavirus can infect humans.

DEVELOPMENT

Coronaviruses are not always confined to the respiratory tract, and under certain conditions they can invade the central nervous system and cause neurological pathologies. The potential for neuroinvasion is well documented in most human coronaviruses (OC-43, 229E, MERS and SARS) and in some animal coronaviruses (porcine haemagglutinating encephalomyelitis coronavirus). Neurological symptoms have been reported in patients affected by COVID-19, such as headache, dizziness, myalgia and anosmia, as well as cases of encephalopathy, encephalitis, necrotising haemorrhagic encephalopathy, stroke, epileptic seizures, rhabdomyolysis and Guillain-Barre syndrome, associated with SARS-CoV-2 infection.

CONCLUSIONS

Future epidemiological studies and case records should elucidate the real incidence of these neurological complications, their pathogenic mechanisms and their therapeutic options.

Authors+Show Affiliations

Universitat Internacional de Catalunya, Barcelona, España. Raigmore Hospital, Inverness, Reino Unido.

Pub Type(s)

Journal Article
Review

Language

eng spa

PubMed ID

32329044

Citation

Carod-Artal, F J.. "Neurological Complications of Coronavirus and COVID-19." Revista De Neurologia, vol. 70, no. 9, 2020, pp. 311-322.
Carod-Artal FJ. Neurological complications of coronavirus and COVID-19. Rev Neurol. 2020;70(9):311-322.
Carod-Artal, F. J. (2020). Neurological complications of coronavirus and COVID-19. Revista De Neurologia, 70(9), 311-322. https://doi.org/10.33588/rn.7009.2020179
Carod-Artal FJ. Neurological Complications of Coronavirus and COVID-19. Rev Neurol. 2020 05 1;70(9):311-322. PubMed PMID: 32329044.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neurological complications of coronavirus and COVID-19. A1 - Carod-Artal,F J, PY - 2020/4/25/entrez PY - 2020/4/25/pubmed PY - 2020/4/29/medline SP - 311 EP - 322 JF - Revista de neurologia JO - Rev Neurol VL - 70 IS - 9 N2 - INTRODUCTION: Clinical and experimental studies have shown that the coronavirus family has a certain tropism for the central nervous system. Seven types of coronavirus can infect humans. DEVELOPMENT: Coronaviruses are not always confined to the respiratory tract, and under certain conditions they can invade the central nervous system and cause neurological pathologies. The potential for neuroinvasion is well documented in most human coronaviruses (OC-43, 229E, MERS and SARS) and in some animal coronaviruses (porcine haemagglutinating encephalomyelitis coronavirus). Neurological symptoms have been reported in patients affected by COVID-19, such as headache, dizziness, myalgia and anosmia, as well as cases of encephalopathy, encephalitis, necrotising haemorrhagic encephalopathy, stroke, epileptic seizures, rhabdomyolysis and Guillain-Barre syndrome, associated with SARS-CoV-2 infection. CONCLUSIONS: Future epidemiological studies and case records should elucidate the real incidence of these neurological complications, their pathogenic mechanisms and their therapeutic options. SN - 1576-6578 UR - https://www.unboundmedicine.com/medline/citation/32329044/Neurological_complications_of_coronavirus_and_COVID_19_ L2 - http://www.revneurol.com/LinkOut/formMedLine.asp?Refer=2020179&Revista=RevNeurol DB - PRIME DP - Unbound Medicine ER -