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Asymptomatic COVID-19 infection in late pregnancy indicated no vertical transmission.
J Med Virol. 2020 09; 92(9):1660-1664.JM

Abstract

This study is to investigate the clinical characteristics of late pregnancy with asymptomatic 2019 novel coronavirus disease (COVID-19) infection, evaluate the outcome of maternal and fetal prognosis, and identify the evidence of intrauterine vertical transmission. A 22-years-old pregnant woman with asymptomatic COVID-19 infection who was admitted to our hospital on 11 February 2020 was enrolled in this study. Clinical data including laboratory test results and chest computed tomography (CT) scanning were collected and reviewed. Diagnosis of late pregnancy with asymptomatic COVID-19 infection was made. Lumbar anesthesia for cesarean section was performed and a female baby was delivered uneventfully, with the Apgar score of 9 to 10 points. Three times of COVID-19 nucleic acid test for the baby was negative after delivery. The puerpera returned to normal after the operation and two times of throat swab COVID-19 nucleic acid test were all negative after antiviral therapy. We reported an asymptomatic COVID-19 pregnant woman with detailed clinical information and our result indicated that for late pregnant women with asymptomatic COVID-19 infection, there might be no intrauterine infection caused by vertical transmission.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, The No. 2 People's Hospital of Hefei City Affiliated to Anhui Medical University, Hefei, China.Department of Obstetrics and Gynecology, The No. 2 People's Hospital of Hefei City Affiliated to Anhui Medical University, Hefei, China.Department of Obstetrics and Gynecology, The No. 2 People's Hospital of Hefei City Affiliated to Anhui Medical University, Hefei, China.Department of Obstetrics and Gynecology, The No. 2 People's Hospital of Hefei City Affiliated to Anhui Medical University, Hefei, China.Department of Biochemistry, School of Basic Medical Science, Chengde Medical University, Chengde, China.Department of Biochemistry, School of Basic Medical Science, Chengde Medical University, Chengde, China.

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

32330313

Citation

Lu, Dawei, et al. "Asymptomatic COVID-19 Infection in Late Pregnancy Indicated No Vertical Transmission." Journal of Medical Virology, vol. 92, no. 9, 2020, pp. 1660-1664.
Lu D, Sang L, Du S, et al. Asymptomatic COVID-19 infection in late pregnancy indicated no vertical transmission. J Med Virol. 2020;92(9):1660-1664.
Lu, D., Sang, L., Du, S., Li, T., Chang, Y., & Yang, X. A. (2020). Asymptomatic COVID-19 infection in late pregnancy indicated no vertical transmission. Journal of Medical Virology, 92(9), 1660-1664. https://doi.org/10.1002/jmv.25927
Lu D, et al. Asymptomatic COVID-19 Infection in Late Pregnancy Indicated No Vertical Transmission. J Med Virol. 2020;92(9):1660-1664. PubMed PMID: 32330313.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Asymptomatic COVID-19 infection in late pregnancy indicated no vertical transmission. AU - Lu,Dawei, AU - Sang,Lin, AU - Du,Shihua, AU - Li,Tao, AU - Chang,Yange, AU - Yang,Xiu-An, Y1 - 2020/04/30/ PY - 2020/03/31/received PY - 2020/04/23/accepted PY - 2020/4/25/pubmed PY - 2020/12/29/medline PY - 2020/4/25/entrez KW - asymptomatic COVID-19 infection KW - intrauterine infection KW - late pregnancy KW - vertical transmission SP - 1660 EP - 1664 JF - Journal of medical virology JO - J Med Virol VL - 92 IS - 9 N2 - This study is to investigate the clinical characteristics of late pregnancy with asymptomatic 2019 novel coronavirus disease (COVID-19) infection, evaluate the outcome of maternal and fetal prognosis, and identify the evidence of intrauterine vertical transmission. A 22-years-old pregnant woman with asymptomatic COVID-19 infection who was admitted to our hospital on 11 February 2020 was enrolled in this study. Clinical data including laboratory test results and chest computed tomography (CT) scanning were collected and reviewed. Diagnosis of late pregnancy with asymptomatic COVID-19 infection was made. Lumbar anesthesia for cesarean section was performed and a female baby was delivered uneventfully, with the Apgar score of 9 to 10 points. Three times of COVID-19 nucleic acid test for the baby was negative after delivery. The puerpera returned to normal after the operation and two times of throat swab COVID-19 nucleic acid test were all negative after antiviral therapy. We reported an asymptomatic COVID-19 pregnant woman with detailed clinical information and our result indicated that for late pregnant women with asymptomatic COVID-19 infection, there might be no intrauterine infection caused by vertical transmission. SN - 1096-9071 UR - https://www.unboundmedicine.com/medline/citation/32330313/Asymptomatic_COVID_19_infection_in_late_pregnancy_indicated_no_vertical_transmission_ L2 - https://doi.org/10.1002/jmv.25927 DB - PRIME DP - Unbound Medicine ER -