Tags

Type your tag names separated by a space and hit enter

The Clinico-Epidemiological Profile of Patients with Gonorrhoea and Challenges in the Management of Neisseria gonorrhoeae Infection in an STI clinic, Ternopil, Ukraine (2013-2018).
J Med Life. 2020 Jan-Mar; 13(1):75-81.JM

Abstract

Gonorrhea is the second most common sexually transmitted infection spreading worldwide and a serious public health problem. However, further data are required to improve the management of gonorrhea. Our aim was to review the features of gonococcal infection and characterize the challenges of its management. A retrospective descriptive study of the medical records of 136 adult patients with gonorrhea that visited Ternopil Regional Sexually Transmitted Infections Clinic (Ukraine) in 2013-2018 was performed. The male-to-female ratio was 6.6:1. Homosexually-acquired gonorrhoea was 3.7%. Also, most patients acquired gonorrhea in Ukraine (98.4%). The mean infectious period lasted 2-16 days, including the incubation period of 1-9 days and the period from the onset of symptoms to the first visit of the clinic of 1-7 days. The probability of N. gonorrhoeae transmission within the frame of the epidemiologic sexual chain was 1:2.4. Concurrent T. vaginalis (39.7%) and C. trachomatis (2.2%) were detected. HIV and syphilis screening rates were 1.6% and 0.7%, respectively. The examining rate of sexual partners was 11%, testing extragenital specimens - 0.7%, screening coverage for HIV - 46.3%, compliance with follow-up visits - 41.9%. Part of patients (16.2%) received monotherapy with clarithromycin, doxycycline, benzylpenicillin, azithromycin, or ofloxacin. The management of N. gonorrhoeae infections was compromised by a low rate of examining sexual partners, females and testing extragenital specimens, screening for HIV, compliance to follow-up visits, access to nucleic acid amplification tests, and receiving questionable or even obsolete antimicrobial treatment. Therefore, more accurate and comprehensive management of gonorrhea is urgently needed in Ukraine.

Authors+Show Affiliations

Department of Functional and Laboratory Diagnostics, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.Department of Clinical Laboratory Diagnostic, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.Department of Clinical Immunology, Allergology and General Patients' Care, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.First Department of Internal Medicine, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.Department of Infectious Diseases with Epidemiology, Skin and Sexually Transmitted Diseases, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.Department of Functional and Laboratory Diagnostics, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32341705

Citation

Boiko, Iryna, et al. "The Clinico-Epidemiological Profile of Patients With Gonorrhoea and Challenges in the Management of Neisseria Gonorrhoeae Infection in an STI Clinic, Ternopil, Ukraine (2013-2018)." Journal of Medicine and Life, vol. 13, no. 1, 2020, pp. 75-81.
Boiko I, Akimova V, Mazur L, et al. The Clinico-Epidemiological Profile of Patients with Gonorrhoea and Challenges in the Management of Neisseria gonorrhoeae Infection in an STI clinic, Ternopil, Ukraine (2013-2018). J Med Life. 2020;13(1):75-81.
Boiko, I., Akimova, V., Mazur, L., Savchenko, I., Kohut, I., & Krynytska, I. (2020). The Clinico-Epidemiological Profile of Patients with Gonorrhoea and Challenges in the Management of Neisseria gonorrhoeae Infection in an STI clinic, Ternopil, Ukraine (2013-2018). Journal of Medicine and Life, 13(1), 75-81. https://doi.org/10.25122/jml-2019-0170
Boiko I, et al. The Clinico-Epidemiological Profile of Patients With Gonorrhoea and Challenges in the Management of Neisseria Gonorrhoeae Infection in an STI Clinic, Ternopil, Ukraine (2013-2018). J Med Life. 2020 Jan-Mar;13(1):75-81. PubMed PMID: 32341705.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Clinico-Epidemiological Profile of Patients with Gonorrhoea and Challenges in the Management of Neisseria gonorrhoeae Infection in an STI clinic, Ternopil, Ukraine (2013-2018). AU - Boiko,Iryna, AU - Akimova,Viorika, AU - Mazur,Lyudmyla, AU - Savchenko,Iryna, AU - Kohut,Ihor, AU - Krynytska,Inna, PY - 2020/4/29/entrez PY - 2020/4/29/pubmed PY - 2020/6/27/medline KW - Neisseria gonorrhoeae KW - epidemiology KW - gonorrhea KW - management KW - sexually transmitted infections SP - 75 EP - 81 JF - Journal of medicine and life JO - J Med Life VL - 13 IS - 1 N2 - Gonorrhea is the second most common sexually transmitted infection spreading worldwide and a serious public health problem. However, further data are required to improve the management of gonorrhea. Our aim was to review the features of gonococcal infection and characterize the challenges of its management. A retrospective descriptive study of the medical records of 136 adult patients with gonorrhea that visited Ternopil Regional Sexually Transmitted Infections Clinic (Ukraine) in 2013-2018 was performed. The male-to-female ratio was 6.6:1. Homosexually-acquired gonorrhoea was 3.7%. Also, most patients acquired gonorrhea in Ukraine (98.4%). The mean infectious period lasted 2-16 days, including the incubation period of 1-9 days and the period from the onset of symptoms to the first visit of the clinic of 1-7 days. The probability of N. gonorrhoeae transmission within the frame of the epidemiologic sexual chain was 1:2.4. Concurrent T. vaginalis (39.7%) and C. trachomatis (2.2%) were detected. HIV and syphilis screening rates were 1.6% and 0.7%, respectively. The examining rate of sexual partners was 11%, testing extragenital specimens - 0.7%, screening coverage for HIV - 46.3%, compliance with follow-up visits - 41.9%. Part of patients (16.2%) received monotherapy with clarithromycin, doxycycline, benzylpenicillin, azithromycin, or ofloxacin. The management of N. gonorrhoeae infections was compromised by a low rate of examining sexual partners, females and testing extragenital specimens, screening for HIV, compliance to follow-up visits, access to nucleic acid amplification tests, and receiving questionable or even obsolete antimicrobial treatment. Therefore, more accurate and comprehensive management of gonorrhea is urgently needed in Ukraine. SN - 1844-3117 UR - https://www.unboundmedicine.com/medline/citation/32341705/The_Clinico_Epidemiological_Profile_of_Patients_with_Gonorrhoea_and_Challenges_in_the_Management_of_Neisseria_gonorrhoeae_Infection_in_an_STI_clinic_Ternopil_Ukraine__2013_2018__ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/32341705/ DB - PRIME DP - Unbound Medicine ER -