Tags

Type your tag names separated by a space and hit enter

Epidemiological and clinical characteristics of 333 confirmed cases with coronavirus disease 2019 in Shanghai, China.
Transbound Emerg Dis. 2020 Jul; 67(4):1697-1707.TE

Abstract

Coronavirus disease 2019 (COVID-19) is an emerging infectious disease first identified in Wuhan City, Hubei Province, China. As of 19 February 2020, there had been 333 confirmed cases reported in Shanghai, China. This study elaborates on the epidemiological and clinical characteristics of COVID-19 based on a descriptive study of the 333 patients infected with COVID-19 in Shanghai for the purpose of probing into this new disease and providing reference. Among the 333 confirmed cases in Shanghai, 172 (51.7%) were males and 161 (48.3%) were females, with a median age of 50 years. 299 (89.8%) cases presented mild symptoms. 139 (41.7%) and 111 (33.3%) cases were infected in Wuhan and Shanghai, respectively. 148 (44.4%) cases once had contact with confirmed cases before onset, while 103 (30.9%) cases had never contacted confirmed cases but they had a sojourn history in Wuhan. The onset date of the first case in Shanghai was 28 December, with the peak appearing on 27 January. The median incubation period of COVID-19 was estimated to be 7.2 days. 207 (62.2%) cases had fever symptoms at the onset, whereas 273 (82.0%) cases experienced fever before hospitalization. 56 (18.6%) adults experienced a decrease in white blood cell and 84 (42.9%) had increased C-reactive protein after onset. Elderly, male and heart disease history were risk factors for severe or critical pneumonia. These findings suggest that most cases experienced fever symptoms and had mild pneumonia. Strengthening the health management of elderly men, especially those with underlying diseases, may help reduce the incidence of severe and critical pneumonia. Time intervals from onset to visit, hospitalization and diagnosis confirmed were all shortened after Shanghai's first-level public health emergency response. Shanghai's experience proves that COVID-19 can be controlled well in megacities.

Authors+Show Affiliations

Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32351037

Citation

Yu, Xiao, et al. "Epidemiological and Clinical Characteristics of 333 Confirmed Cases With Coronavirus Disease 2019 in Shanghai, China." Transboundary and Emerging Diseases, vol. 67, no. 4, 2020, pp. 1697-1707.
Yu X, Sun X, Cui P, et al. Epidemiological and clinical characteristics of 333 confirmed cases with coronavirus disease 2019 in Shanghai, China. Transbound Emerg Dis. 2020;67(4):1697-1707.
Yu, X., Sun, X., Cui, P., Pan, H., Lin, S., Han, R., Jiang, C., Fang, Q., Kong, D., Zhu, Y., Zheng, Y., Gong, X., Xiao, W., Mao, S., Jin, B., Wu, H., & Fu, C. (2020). Epidemiological and clinical characteristics of 333 confirmed cases with coronavirus disease 2019 in Shanghai, China. Transboundary and Emerging Diseases, 67(4), 1697-1707. https://doi.org/10.1111/tbed.13604
Yu X, et al. Epidemiological and Clinical Characteristics of 333 Confirmed Cases With Coronavirus Disease 2019 in Shanghai, China. Transbound Emerg Dis. 2020;67(4):1697-1707. PubMed PMID: 32351037.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiological and clinical characteristics of 333 confirmed cases with coronavirus disease 2019 in Shanghai, China. AU - Yu,Xiao, AU - Sun,Xiaodong, AU - Cui,Peng, AU - Pan,Hao, AU - Lin,Sheng, AU - Han,Ruobing, AU - Jiang,Chenyan, AU - Fang,Qiwen, AU - Kong,Dechuan, AU - Zhu,Yiyi, AU - Zheng,Yaxu, AU - Gong,Xiaohuan, AU - Xiao,Wenjia, AU - Mao,Shenghua, AU - Jin,Bihong, AU - Wu,Huanyu, AU - Fu,Chen, Y1 - 2020/05/13/ PY - 2020/03/10/received PY - 2020/03/30/revised PY - 2020/04/25/accepted PY - 2020/5/1/pubmed PY - 2020/7/15/medline PY - 2020/5/1/entrez KW - COVID-19 KW - Shanghai KW - clinical characteristics KW - epidemiology SP - 1697 EP - 1707 JF - Transboundary and emerging diseases JO - Transbound Emerg Dis VL - 67 IS - 4 N2 - Coronavirus disease 2019 (COVID-19) is an emerging infectious disease first identified in Wuhan City, Hubei Province, China. As of 19 February 2020, there had been 333 confirmed cases reported in Shanghai, China. This study elaborates on the epidemiological and clinical characteristics of COVID-19 based on a descriptive study of the 333 patients infected with COVID-19 in Shanghai for the purpose of probing into this new disease and providing reference. Among the 333 confirmed cases in Shanghai, 172 (51.7%) were males and 161 (48.3%) were females, with a median age of 50 years. 299 (89.8%) cases presented mild symptoms. 139 (41.7%) and 111 (33.3%) cases were infected in Wuhan and Shanghai, respectively. 148 (44.4%) cases once had contact with confirmed cases before onset, while 103 (30.9%) cases had never contacted confirmed cases but they had a sojourn history in Wuhan. The onset date of the first case in Shanghai was 28 December, with the peak appearing on 27 January. The median incubation period of COVID-19 was estimated to be 7.2 days. 207 (62.2%) cases had fever symptoms at the onset, whereas 273 (82.0%) cases experienced fever before hospitalization. 56 (18.6%) adults experienced a decrease in white blood cell and 84 (42.9%) had increased C-reactive protein after onset. Elderly, male and heart disease history were risk factors for severe or critical pneumonia. These findings suggest that most cases experienced fever symptoms and had mild pneumonia. Strengthening the health management of elderly men, especially those with underlying diseases, may help reduce the incidence of severe and critical pneumonia. Time intervals from onset to visit, hospitalization and diagnosis confirmed were all shortened after Shanghai's first-level public health emergency response. Shanghai's experience proves that COVID-19 can be controlled well in megacities. SN - 1865-1682 UR - https://www.unboundmedicine.com/medline/citation/32351037/Epidemiological_and_clinical_characteristics_of_333_confirmed_cases_with_coronavirus_disease_2019_in_Shanghai_China_ L2 - https://doi.org/10.1111/tbed.13604 DB - PRIME DP - Unbound Medicine ER -