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Mycoplasma Pneumoniae Induced Rash and Mucositis with Bilateral Otitis Media and Sinusitis.
Cureus. 2020 Mar 28; 12(3):e7449.C

Abstract

Mycoplasma pneumoniae induced rash and mucositis (MIRM) is a recently identified clinical entity, which describes a subset of extrapulmonary manifestations resulting from Mycoplasma pneumonia infection. Patients present with a wide variety of symptoms including cough, dyspnea, mucositis, conjunctivitis, with or without a variable cutaneous rash. A 24-year-old male presented to the emergency department with worsening dyspnea and new-onset oral, ocular, and genital mucosal lesions. The patient was also found to have bilateral otitis media with tympanic membrane rupture and ethmoid sinusitis upon further evaluation. The patient was originally diagnosed with atypical pneumonia leading to acute hypoxic respiratory failure and was admitted to inpatient care. Work-up revealed positive Mycoplasma pneumoniae immunoglobulin M, and the patient was subsequently diagnosed with MIRM. The patient was provided with supportive care as well as systemic antibiotics, and he fully recovered by day 12 without complication. No standardized treatment guidelines exist for MIRM, and it is universally accepted that supportive management is the mainstay of treatment, consisting of pain management, intravenous hydration, and mucosal care. Although the majority of MIRM patients are generally known to have a full recovery (81%), a variety of ocular, oral, and genital complications have been noted in the literature. Here we present a unique case of MIRM in a 24-year-old male who also had ethmoid sinusitis and bilateral otitis media with unilateral tympanic membrane perforation - two head and neck symptoms not described in previous literature.

Authors+Show Affiliations

Otolaryngology, McLaren Oakland Hospital, Pontiac, USA.Otolaryngology, McLaren Oakland Hospital, Pontiac, USA.Otolaryngology, McLaren Oakland Hospital, Pontiac, USA.Otolaryngology, McLaren Oakland Hospital, Pontiac, USA.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

32351828

Citation

Lofgren, Daniel H., et al. "Mycoplasma Pneumoniae Induced Rash and Mucositis With Bilateral Otitis Media and Sinusitis." Cureus, vol. 12, no. 3, 2020, pp. e7449.
Lofgren DH, Lenkeit C, Palanisamy J, et al. Mycoplasma Pneumoniae Induced Rash and Mucositis with Bilateral Otitis Media and Sinusitis. Cureus. 2020;12(3):e7449.
Lofgren, D. H., Lenkeit, C., Palanisamy, J., & Brown, J. (2020). Mycoplasma Pneumoniae Induced Rash and Mucositis with Bilateral Otitis Media and Sinusitis. Cureus, 12(3), e7449. https://doi.org/10.7759/cureus.7449
Lofgren DH, et al. Mycoplasma Pneumoniae Induced Rash and Mucositis With Bilateral Otitis Media and Sinusitis. Cureus. 2020 Mar 28;12(3):e7449. PubMed PMID: 32351828.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mycoplasma Pneumoniae Induced Rash and Mucositis with Bilateral Otitis Media and Sinusitis. AU - Lofgren,Daniel H, AU - Lenkeit,Christopher, AU - Palanisamy,Jaishree, AU - Brown,Jens, Y1 - 2020/03/28/ PY - 2020/5/1/entrez PY - 2020/5/1/pubmed PY - 2020/5/1/medline KW - mirm KW - mucositis KW - mycoplasma KW - mycoplasma pneumoniae KW - mycoplasma pneumoniae induced rash and mucositis KW - otitis media KW - rash KW - sinusitis SP - e7449 EP - e7449 JF - Cureus JO - Cureus VL - 12 IS - 3 N2 - Mycoplasma pneumoniae induced rash and mucositis (MIRM) is a recently identified clinical entity, which describes a subset of extrapulmonary manifestations resulting from Mycoplasma pneumonia infection. Patients present with a wide variety of symptoms including cough, dyspnea, mucositis, conjunctivitis, with or without a variable cutaneous rash. A 24-year-old male presented to the emergency department with worsening dyspnea and new-onset oral, ocular, and genital mucosal lesions. The patient was also found to have bilateral otitis media with tympanic membrane rupture and ethmoid sinusitis upon further evaluation. The patient was originally diagnosed with atypical pneumonia leading to acute hypoxic respiratory failure and was admitted to inpatient care. Work-up revealed positive Mycoplasma pneumoniae immunoglobulin M, and the patient was subsequently diagnosed with MIRM. The patient was provided with supportive care as well as systemic antibiotics, and he fully recovered by day 12 without complication. No standardized treatment guidelines exist for MIRM, and it is universally accepted that supportive management is the mainstay of treatment, consisting of pain management, intravenous hydration, and mucosal care. Although the majority of MIRM patients are generally known to have a full recovery (81%), a variety of ocular, oral, and genital complications have been noted in the literature. Here we present a unique case of MIRM in a 24-year-old male who also had ethmoid sinusitis and bilateral otitis media with unilateral tympanic membrane perforation - two head and neck symptoms not described in previous literature. SN - 2168-8184 UR - https://www.unboundmedicine.com/medline/citation/32351828/Mycoplasma_Pneumoniae_Induced_Rash_and_Mucositis_with_Bilateral_Otitis_Media_and_Sinusitis_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/32351828/ DB - PRIME DP - Unbound Medicine ER -
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