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Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study.
J Clin Virol. 2020 06; 127:104378.JC

Abstract

BACKGROUND

An outbreak of COVID-19 in Iran has spread throughout the country. Identifying the epidemiological characteristics of this disease will help to make appropriate decisions and thus control the epidemic. The aim of this study was characterization of the epidemiological features of COVID-19 in Iran.

METHODS

In this retrospective study, data related to the epidemiological characteristics of COVID-19 patients admitted to Baqiyatallah Hospital in Tehran, Iran, from 19 February 2020 to 15 April 2020 have been analyzed and reported. Patient characteristics including age, gender and underlying diseases were investigated. Data were collected through patient records. Sex ratio, Case Fatality Rate (CFR) and daily trend of cases were also determined. A multiple logistic regression analysis was also performed to assess affecting factors on mortality.

RESULTS

From February 19, 2020 to April 15, 2020, 12870 patients referred to the hospital emergency department, of which 2968 were hospitalized with COVID-19 diagnosis. The majority of cases were in the age group of 50 to 60 years of old. The male-to-female ratio was 1.93:1. A total of 239 deaths occurred among all cases for an overall CFR of 1.85% based on the total number of patients (both outpatient and inpatient) and 8.06% among hospitalized patients. Out of all patients 10.89% had comorbidity. Diabetes, chronic respiratory diseases, hypertension, cardiovascular diseases, chronic Kidney diseases and cancer were the most common comorbidities with 3.81, 2.02 , 1.99 , 1.25, 0.60 and 0.57 %, respectively. Male gender (OR=1.45, 95% CI: 1.08-1.96), older age (OR=1.05, 95% CI: 1.04-1.06) and having underlying diseases (OR=1.53, 95% CI: 1.04-2.24) were significantly associated with mortality.

CONCLUSIONS

The results of this study showed that Male gender, older age and having comorbidities were significantly associated with the risk of death among COVID-19 patients. It is important to pay special attention to male elderly patients with underlying diseases.

Authors+Show Affiliations

Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Atherosclerosis Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.Trauma Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Nanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: msepandi@bmsu.ac.ir.Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.Trauma Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Atherosclerosis Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran.Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran; Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32353762

Citation

Nikpouraghdam, Mohamad, et al. "Epidemiological Characteristics of Coronavirus Disease 2019 (COVID-19) Patients in IRAN: a Single Center Study." Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology, vol. 127, 2020, p. 104378.
Nikpouraghdam M, Jalali Farahani A, Alishiri G, et al. Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study. J Clin Virol. 2020;127:104378.
Nikpouraghdam, M., Jalali Farahani, A., Alishiri, G., Heydari, S., Ebrahimnia, M., Samadinia, H., Sepandi, M., Jafari, N. J., Izadi, M., Qazvini, A., Dorostkar, R., Tat, M., Shahriary, A., Farnoosh, G., Hosseini Zijoud, S. R., Taghdir, M., Alimohamadi, Y., Abbaszadeh, S., Gouvarchin Ghaleh, H. E., & Bagheri, M. (2020). Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study. Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology, 127, 104378. https://doi.org/10.1016/j.jcv.2020.104378
Nikpouraghdam M, et al. Epidemiological Characteristics of Coronavirus Disease 2019 (COVID-19) Patients in IRAN: a Single Center Study. J Clin Virol. 2020;127:104378. PubMed PMID: 32353762.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study. AU - Nikpouraghdam,Mohamad, AU - Jalali Farahani,Alireza, AU - Alishiri,GholamHossein, AU - Heydari,Soleyman, AU - Ebrahimnia,Mehdi, AU - Samadinia,Hossein, AU - Sepandi,Mojtaba, AU - Jafari,Nematollah Jonaidi, AU - Izadi,Morteza, AU - Qazvini,Ali, AU - Dorostkar,Ruhollah, AU - Tat,Mahdi, AU - Shahriary,Alireza, AU - Farnoosh,Gholamreza, AU - Hosseini Zijoud,Seyed Reza, AU - Taghdir,Maryam, AU - Alimohamadi,Yousef, AU - Abbaszadeh,Sepideh, AU - Gouvarchin Ghaleh,Hadi Esmaeili, AU - Bagheri,Mahdi, Y1 - 2020/04/21/ PY - 2020/04/16/received PY - 2020/04/19/accepted PY - 2020/5/1/pubmed PY - 2020/6/17/medline PY - 2020/5/1/entrez KW - COVID-19 KW - Case Fatality Rate KW - Comorbidity KW - Epidemiology KW - IRAN KW - SARS-CoV-2 SP - 104378 EP - 104378 JF - Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology JO - J Clin Virol VL - 127 N2 - BACKGROUND: An outbreak of COVID-19 in Iran has spread throughout the country. Identifying the epidemiological characteristics of this disease will help to make appropriate decisions and thus control the epidemic. The aim of this study was characterization of the epidemiological features of COVID-19 in Iran. METHODS: In this retrospective study, data related to the epidemiological characteristics of COVID-19 patients admitted to Baqiyatallah Hospital in Tehran, Iran, from 19 February 2020 to 15 April 2020 have been analyzed and reported. Patient characteristics including age, gender and underlying diseases were investigated. Data were collected through patient records. Sex ratio, Case Fatality Rate (CFR) and daily trend of cases were also determined. A multiple logistic regression analysis was also performed to assess affecting factors on mortality. RESULTS: From February 19, 2020 to April 15, 2020, 12870 patients referred to the hospital emergency department, of which 2968 were hospitalized with COVID-19 diagnosis. The majority of cases were in the age group of 50 to 60 years of old. The male-to-female ratio was 1.93:1. A total of 239 deaths occurred among all cases for an overall CFR of 1.85% based on the total number of patients (both outpatient and inpatient) and 8.06% among hospitalized patients. Out of all patients 10.89% had comorbidity. Diabetes, chronic respiratory diseases, hypertension, cardiovascular diseases, chronic Kidney diseases and cancer were the most common comorbidities with 3.81, 2.02 , 1.99 , 1.25, 0.60 and 0.57 %, respectively. Male gender (OR=1.45, 95% CI: 1.08-1.96), older age (OR=1.05, 95% CI: 1.04-1.06) and having underlying diseases (OR=1.53, 95% CI: 1.04-2.24) were significantly associated with mortality. CONCLUSIONS: The results of this study showed that Male gender, older age and having comorbidities were significantly associated with the risk of death among COVID-19 patients. It is important to pay special attention to male elderly patients with underlying diseases. SN - 1873-5967 UR - https://www.unboundmedicine.com/medline/citation/32353762/Epidemiological_characteristics_of_coronavirus_disease_2019__COVID_19__patients_in_IRAN:_A_single_center_study_ DB - PRIME DP - Unbound Medicine ER -