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SARS-CoV-2 and myocardial injury: Few answers, many questions.
Cleve Clin J Med. 2020 08 31; 87(9):521-525.CC

Abstract

Acute cardiac injury, defined as an elevated high-sensitivity troponin I or troponin T upon admission or during hospitalization, is common in patients with COVID-19, occurring in 10% to 35% of patients depending on the assay used and the population studied. Even though the mechanisms of SARS-CoV-2 myocardial injury are not well defined, type 1 myocardial infarction and fulminant myocarditis are rare. Often, acute cardiac injury occurs in patients with elevated inflammatory markers, and both are associated with worse outcomes. However, the extent to which treatments should differ for patients with acute cardiac injury, heightened systemic inflammation, or both, is unknown.

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Publisher Full Text

Authors+Show Affiliations

Cremer PC
Department of Cardiovascular Imaging, Heart, Vascular, and Thoracic Institute, Cleveland Clinic cremerp@ccf.org.

MeSH

Acute DiseaseBetacoronavirusCOVID-19Coronavirus InfectionsHospitalizationHumansInflammationMyocardial InfarctionMyocarditisPandemicsPneumonia, ViralSARS-CoV-2

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32371557

Citation

Cremer, Paul C.. "SARS-CoV-2 and Myocardial Injury: Few Answers, Many Questions." Cleveland Clinic Journal of Medicine, vol. 87, no. 9, 2020, pp. 521-525.
Cremer PC. SARS-CoV-2 and myocardial injury: Few answers, many questions. Cleve Clin J Med. 2020;87(9):521-525.
Cremer, P. C. (2020). SARS-CoV-2 and myocardial injury: Few answers, many questions. Cleveland Clinic Journal of Medicine, 87(9), 521-525. https://doi.org/10.3949/ccjm.87a.ccc001
Cremer PC. SARS-CoV-2 and Myocardial Injury: Few Answers, Many Questions. Cleve Clin J Med. 2020 08 31;87(9):521-525. PubMed PMID: 32371557.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - SARS-CoV-2 and myocardial injury: Few answers, many questions. A1 - Cremer,Paul C, Y1 - 2020/08/31/ PY - 2020/5/7/pubmed PY - 2020/9/10/medline PY - 2020/5/7/entrez SP - 521 EP - 525 JF - Cleveland Clinic journal of medicine JO - Cleve Clin J Med VL - 87 IS - 9 N2 - Acute cardiac injury, defined as an elevated high-sensitivity troponin I or troponin T upon admission or during hospitalization, is common in patients with COVID-19, occurring in 10% to 35% of patients depending on the assay used and the population studied. Even though the mechanisms of SARS-CoV-2 myocardial injury are not well defined, type 1 myocardial infarction and fulminant myocarditis are rare. Often, acute cardiac injury occurs in patients with elevated inflammatory markers, and both are associated with worse outcomes. However, the extent to which treatments should differ for patients with acute cardiac injury, heightened systemic inflammation, or both, is unknown. SN - 1939-2869 UR - https://www.unboundmedicine.com/medline/citation/32371557/SARS_CoV_2_and_myocardial_injury:_Few_answers_many_questions_ L2 - https://www.ccjm.org/cgi/pmidlookup?view=long&pmid=32371557 DB - PRIME DP - Unbound Medicine ER -