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COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus.
Discoveries (Craiova). 2020 Apr 26; 8(2):e108.D

Abstract

An epidemic of extreme respiratory deterrence, pneumonia and shortness of breath, the SARS-CoV-2 viral infection began in Wuhan, Hubei Province, China in December 2019, and rapidly spread across China and beyond, with human to human transmission. On February 12, 2020, World Health Organization officially named the new coronavirus disease as coronavirus disease 19 (COVID-19). Most COVID-19 patients were diagnosed with pneumonia and many were treated using Chinese medicines and other secondary therapies. As of April 22, 2020, the total figure of infected patients has crossed 2.6 million people worldwide with over 180,000 deaths and 700,000 patients that have recovered. Preliminary reports suggest that certain drugs, such as chloroquine and antiviral nucleotide analogues such as remdesivir, which inhibit viral replication, can target the new coronavirus, although their usefulness in the clinic is still under debate. An expert US committee developed the US NIH guidelines for COVID-19 treatment, which was just released and will be regularly updated. This manuscript reviews the epidemiology, etiology, mortality, COVID-19 clinical symptoms, and potential therapeutic drugs, while highlighting the seriousness and damage-induced by SARS-CoV-2.

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Authors+Show Affiliations

Jan H
Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.
Faisal S
Department of Biotechnology, Bacha Khan University, Charsadda, Pakistan.
Khan A
Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.
Khan S
Department of Microbiology, Abdul Wali Khan University, Mardan, Pakistan.
Usman H
Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.
Liaqat R
Department of Botany, Bacha Khan University, Charsadda, Pakistan.
Shah SA
Department of Biotechnology, Bacha Khan University, Charsadda, Pakistan.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32377559

Citation

Jan, Hasnain, et al. "COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus." Discoveries (Craiova, Romania), vol. 8, no. 2, 2020, pp. e108.
Jan H, Faisal S, Khan A, et al. COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus. Discoveries (Craiova). 2020;8(2):e108.
Jan, H., Faisal, S., Khan, A., Khan, S., Usman, H., Liaqat, R., & Shah, S. A. (2020). COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus. Discoveries (Craiova, Romania), 8(2), e108. https://doi.org/10.15190/d.2020.5
Jan H, et al. COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus. Discoveries (Craiova). 2020 Apr 26;8(2):e108. PubMed PMID: 32377559.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus. AU - Jan,Hasnain, AU - Faisal,Shah, AU - Khan,Ayyaz, AU - Khan,Shahzar, AU - Usman,Hazrat, AU - Liaqat,Rabia, AU - Shah,Sajjad Ali, Y1 - 2020/04/26/ PY - 2020/5/8/entrez PY - 2020/5/8/pubmed PY - 2020/5/8/medline KW - COVID-19 KW - Chloroquine KW - MERS KW - Morbidity KW - Rendesivir. KW - SARS-CoV-2 SP - e108 EP - e108 JF - Discoveries (Craiova, Romania) JO - Discoveries (Craiova) VL - 8 IS - 2 N2 - An epidemic of extreme respiratory deterrence, pneumonia and shortness of breath, the SARS-CoV-2 viral infection began in Wuhan, Hubei Province, China in December 2019, and rapidly spread across China and beyond, with human to human transmission. On February 12, 2020, World Health Organization officially named the new coronavirus disease as coronavirus disease 19 (COVID-19). Most COVID-19 patients were diagnosed with pneumonia and many were treated using Chinese medicines and other secondary therapies. As of April 22, 2020, the total figure of infected patients has crossed 2.6 million people worldwide with over 180,000 deaths and 700,000 patients that have recovered. Preliminary reports suggest that certain drugs, such as chloroquine and antiviral nucleotide analogues such as remdesivir, which inhibit viral replication, can target the new coronavirus, although their usefulness in the clinic is still under debate. An expert US committee developed the US NIH guidelines for COVID-19 treatment, which was just released and will be regularly updated. This manuscript reviews the epidemiology, etiology, mortality, COVID-19 clinical symptoms, and potential therapeutic drugs, while highlighting the seriousness and damage-induced by SARS-CoV-2. SN - 2359-7232 UR - https://www.unboundmedicine.com/medline/citation/32377559/COVID_19:_Review_of_Epidemiology_and_Potential_Treatments_Against_2019_Novel_Coronavirus_ DB - PRIME DP - Unbound Medicine ER -